VOLUME 14, JANUARY 1, 2009, ISSUE 1, PAGES 1-397

Frontiers in Bioscience proudly launches this issue by a paper from Dr Freid Murad,
1998 Nobel Laureate
in Medicine for his discovery of nitric oxide as a signalling molecule in the cardiovascular system

Discovery of the nitric oxide signaling pathway and targets for drug development
Nathan S. Bryan, Ka Bian, Ferid Murad

[Frontiers in Bioscience 14, 1-18, January 1, 2009]
[Abstract] [Full text] [PDF Type I] [PDF Type II] [[PDF Type II-Open Access]
[Order reprint Ms#:3228] [Help] [PubMed No] [DOI No:10.2741/3228]
[Managing Editor: Pal Pacher]

AMPK: Lessons from transgenic and knockout animals
Benoit Viollet, Yoni Athea, Remi Mounier, Bruno Guigas, Elham Zarrinpashneh, Sandrine Horman, Louise Lantier, Sophie Hebrard, Jocelyne Devin-Leclerc, Christophe Beauloye, Marc Foretz, Fabrizio Andreelli, Renée Ventura-Clapier, Luc Bertrand

[Frontiers in Bioscience 14, 19-44, January 1, 2009]
[Abstract] [Full text] [PDF Type I] [PDF Type II]
[Order reprint Ms#:3229] [Help] [PubMed No] [DOI No:10.2741/3229]
[Managing Editor: Lance Macaulay]

The integrative function of TRPC channels
Kirill Kiselyov, Randen L Patterson

[Frontiers in Bioscience 14, 45-58, January 1, 2009]
[Abstract] [Full text] [PDF Type I] [PDF Type II]
[Order reprint Ms#:3230] [Help] [PubMed No] [DOI No:10.2741/3230]
[Managing Editor: Peter Koulen]

Genetic engineering of plant food with reduced allergenicity
Stephan Scheurer, Sophia Sonnewald

[Frontiers in Bioscience 14, 59-71, January 1, 2009]
[Abstract] [Full text] [PDF Type I] [PDF Type II]
[Order reprint Ms#:3231] [Help] [PubMed No] [DOI No:10.2741/3231]
[Managing Editor: Ernesto Enrique]

The molecular "Jekyll and Hyde" duality of PARP1 in cell death and cell survival
Paul O. Hassa

[Frontiers in Bioscience 14, 72-111, January 1, 2009]
[Abstract] [Full text] [PDF Type I] [PDF Type II]
[Order reprint Ms#:3232] [Help] [PubMed No] [DOI No:10.2741/3232]
[Managing Editor: Michael Hottiger]

Neural-immune system interactions in Xenopus
Kevin S. Kinney, Nicholas Cohen

[Frontiers in Bioscience 14, 112-129, January 1, 2009]
[Abstract] [Full text] [PDF Type I] [PDF Type II]
[Order reprint Ms#:3233] [Help] [PubMed No] [DOI No:10.2741/3233]
[Managing Editor: Jacques Robert]

Diversity of the FcR- and KIR-related genes in an amphibian Xenopus
Sergey V. Guselnikov, Thaminda Ramanayake, Jacques Robert, Alexander V. Taranin

[Frontiers in Bioscience 14, 130-140, January 1, 2009]
[Abstract] [Full text] [PDF Type I] [PDF Type II]
[Order reprint Ms#:3234] [Help] [PubMed No] [DOI No:10.2741/3234]
[Managing Editor: Jacques Robert]

The immune system is involved in Xenopus metamorphosis
Yumi Izutsu

[Frontiers in Bioscience 14, 141-149, January 1, 2009]
[Abstract] [Full text] [PDF Type I] [PDF Type II]
[Order reprint Ms#:3235] [Help] [PubMed No] [DOI No:10.2741/3235]
[Managing Editor: Jacques Robert]

The role of platelets in acute lung injury (ALI)
Alexander Zarbock, Klaus Ley

[Frontiers in Bioscience 14, 150-158, January 1, 2009]
[Abstract] [Full text] [PDF Type I] [PDF Type II]
[Order reprint Ms#:3236] [Help] [PubMed No] [DOI No:10.2741/3236]
[Managing Editor: Patrick Andre]

Epidermal growth factor receptor modulates the tumorigenic potential of melanoma
Arlhee Diaz, Eduardo Suarez, Rances Blanco, Armando Lopez, Enrique Montero

[Frontiers in Bioscience 14, 159-166, January 1, 2009]
[Abstract] [Full text] [PDF Type I] [PDF Type II]
[Order reprint Ms#:3237] [Help] [PubMed No] [DOI No:10.2741/3237]
[Managing Editor: Stefania Staibano]

Tumorigenesis and anti-tumor immune responses in Xenopus
Ana Goyos, Jacques Robert

[Frontiers in Bioscience 14, 167-176, January 1, 2009]
[Abstract] [Full text] [PDF Type I] [PDF Type II]
[Order reprint Ms#:3238] [Help] [PubMed No] [DOI No:10.2741/3238]
[Managing Editor: Jacques Robert]

The fate of duplicated immunity genes in the dodecaploid Xenopus ruwenzoriensis
Louis Du Pasquier, Melanie Wilson, Benedicte Sammut

[Frontiers in Bioscience 14, 177-191, January 1, 2009]
[Abstract] [Full text] [PDF Type I] [PDF Type II]
[Order reprint Ms#:3239] [Help] [PubMed No] [DOI No:10.2741/3239]
[Managing Editor: Jacquest Robert]

Therapeutic interventions and oxidative stress in diabetes
Shilpa Rahangdale, Susie Yim Yeh, Atul Malhotra, Aristidis Veves

[Frontiers in Bioscience 14, 192-209, January 1, 2009]
[Abstract] [Full text] [PDF Type I] [PDF Type II]
[Order reprint Ms#:3240] [Help] [PubMed No] [DOI No:10.2741/3240]
[Managing Editor: Pal Patcher]

Stromal cells
Muriel Vayssade, Marie-Danielle Nagel

[Frontiers in Bioscience 14, 210-224, January 1, 2009]
[Abstract] [Full text] [PDF Type I] [PDF Type II]
[Order reprint Ms#:3241] [Help] [PubMed No] [DOI No:10.2741/3241]
[Managing Editor: Patrick Vermette]

Transposon-mediated transgenesis in the frog: New tools for biomedical and developmental studies
Donald Albert Yergeau, Paul Evan Mead

[Frontiers in Bioscience 14, 225-236, January 1, 2009]
[Abstract] [Full text] [PDF Type I] [PDF Type II]
[Order reprint Ms#:3242] [Help] [PubMed No] [DOI No:10.2741/3242]
[Managing Editor: Jacques Robert]

Role of xanthine oxidoreductase in cardiac nitroso-redox imbalance
Konstantinos Tziomalos, Joshua M. Hare

[Frontiers in Bioscience 14, 237-262, January 1, 2009]
[Abstract] [Full text] [PDF Type I] [PDF Type II]
[Order reprint Ms#:3243] [Help] [PubMed No] [DOI No:10.2741/3243]
[Managing Editor: Pal Pacher]

Superoxide, no, peroxynitrite and PARP in circulatory shock and inflammation
Emanuela Esposito, Salvatore Cuzzocrea

[Frontiers in Bioscience 14, 263-296, January 1, 2009]
[Abstract] [Full text] [PDF Type I] [PDF Type II]
[Order reprint Ms#:3244] [Help] [PubMed No] [DOI No:10.2741/3244]
[Managing Editor: Pal Pacher]

Potential application of RNAi for understanding and therapy of neurodegenerative diseases
Elena I. Schwartz

[Frontiers in Bioscience 14, 297-320, January 1, 2009]
[Abstract] [Full text] [PDF Type I] [PDF Type II]
[Order reprint Ms#:3245] [Help] [PubMed No] [DOI No:10.2741/3245]
[Managing Editor: Zhi-Gang Jiang]

The roles of gamma-band oscillatory synchrony in human visual cognition
Catherine Tallon-Baudry

[Frontiers in Bioscience 14, 321-332, January 1, 2009]
[Abstract] [Full text] [PDF Type I] [PDF Type II]
[Order reprint Ms#:3246] [Help] [PubMed No] [DOI No:10.2741/3246]
[Managing Editor: Stephane Molotchnikoff]

Natural Tregs and autoimmunity
Antonio La Cava

[Frontiers in Bioscience 14, 333-343, January 1, 2009]
[Abstract] [Full text] [PDF Type I] [PDF Type II]
[Order reprint Ms#:3247] [Help] [PubMed No] [DOI No:10.2741/3247]
[Managing Editor: Antonio La Cava]

Antigen processing patterns determine GAD65-specific regulation vs. pathogenesis
Yang D. Dai, Eli E. Sercarz

[Frontiers in Bioscience 14, 344-351, January 1, 2009]
[Abstract] [Full text] [PDF Type I] [PDF Type II]
[Order reprint Ms#:3248] [Help] [PubMed No] [DOI No:10.2741/3248]
[Managing Editor: Antonio La Cava]

IGF-IR in neuroprotection and brain tumors
Elisa Gualco, Jin Ying Wang, Luis Del Valle, Katarzyna Urbanska, Francesca Peruzzi, Kamel Khalili, Shohreh Amini, Krzysztof Reiss

[Frontiers in Bioscience 14, 352-375, January 1, 2009]
[Abstract] [Full text] [PDF Type I] [PDF Type II]
[Order reprint Ms#:3249] [Help] [PubMed No] [DOI No:10.2741/3249]
[Managing Editor: Francesca Peruzzi]

Vitagenes, dietary antioxidants and neuroprotection in neurodegenerative diseases
Vittorio Calabrese, Carolin Cornelius, Cesare Mancuso, Eugenio Barone, Stella Calafato, Timothy Bates, Enrico Rizzarelli and Albena T. Dinkova Kostova

[Frontiers in Bioscience 14, 376-397, January 1, 2009]
[Abstract] [Full text] [PDF Type I] [PDF Type II]
[Order reprint Ms#:3250] [Help] [PubMed No] [DOI No:10.2741/3250]
[Managing Editor: Ken-ichiro Fukuchi]

VOLUME 14, JANUARY 1, 2009, ISSUE 2, PAGES 398-795

Insights into chromatin remodelers in mesenchymal stem cells and differentiation
Benayahu Dafna, Shefer Gabi, Shur Irena

[Frontiers in Bioscience 14, 398-409, January 1, 2009]
[Abstract] [Full text] [PDF Type I] [PDF Type II]
[Order reprint Ms#:3251] [Help] [PubMed No] [DOI No:10.2741/3251]
[Managing Editor: Eran Meshorer]

The NMN/NaMN adenylyltransferase (NMNAT) protein family
Corinna Lau, Marc Niere, Mathias Ziegler

[Frontiers in Bioscience 14, 410-431, January 1, 2009]
[Abstract] [Full text] [PDF Type I] [PDF Type II]
[Order reprint Ms#:3252] [Help] [PubMed No] [DOI No:10.2741/3252]
[Managing Editor: Michael Hottiger]

Response and adaptation of skeletal muscle to denervation stress: the role of apoptosis in muscle loss
Parco M. Siu, Stephen E. Alway

[Frontiers in Bioscience 14, 432-452, January 1, 2009]
[Abstract] [Full text] [PDF Type I] [PDF Type II]
[Order reprint Ms#:3253] [Help] [PubMed No] [DOI No:10.2741/3253]
[Managing Editor: Liu Yuefei]

Epigenetic regulation of cystatins in cancer
Ashley G. Rivenbark, William B. Coleman

[Frontiers in Bioscience 14, 453-462, January 1, 2009]
[Abstract] [Full text] [PDF Type I] [PDF Type II]
[Order reprint Ms#:3254] [Help] [PubMed No] [DOI No:10.2741/3254]
[Managing Editor: James Cox]

Cystatins and cancer
James L. Cox

[Frontiers in Bioscience 14, 463-474, January 1, 2009]
[Abstract] [Full text] [PDF Type I] [PDF Type II]
[Order reprint Ms#:3255] [Help] [PubMed No] [DOI No:10.2741/3255]
[Managing Editor: James L. Cox]

PML links aberrant cytokine signaling and oncogenic stress to cellular senescence
Veronique Bourdeau, David Baudry, Gerardo Ferbeyre

[Frontiers in Bioscience 14, 475-485, January 1, 2009]
[Abstract] [Full text] [PDF Type I] [PDF Type II]
[Order reprint Ms#:3256] [Help] [PubMed No] [DOI No:10.2741/3256]
[Managing Editor: Borden Katherine]

Role of CaMKII for signaling and regulation in the heart
Lars S. Maier

[Frontiers in Bioscience 14, 486-496, January 1, 2009]
[Abstract] [Full text] [PDF Type I] [PDF Type II]
[Order reprint Ms#:3257] [Help] [PubMed No] [DOI No:10.2741/3257]
[Managing Editor: Rosana A. Bassani]

Perspectives in PML: a unifying framework for PML function
Katherine L.B. Borden, Biljana Culjkovic

[Frontiers in Bioscience 14, 497-509, January 1, 2009]
[Abstract] [Full text] [PDF Type I] [PDF Type II]
[Order reprint Ms#:3258] [Help] [PubMed No] [DOI No:10.2741/3258]
[Managing Editor: Katherine Borden]

Phosphatidylinositol 3-kinase: a key regulator in adherens junction formation and function
Nathalie Rivard

[Frontiers in Bioscience 14, 510-522, January 1, 2009]
[Abstract] [Full text] [PDF Type I] [PDF Type II]
[Order reprint Ms#:3259] [Help] [PubMed No] [DOI No:10.2741/3259]
[Managing Editor: Andrei I. Ivanov]

Structure and sequence determinants of aggregation investigated with molecular dynamics
Elisabetta Moroni, Guido Scarabelli, Giorgio Colombo

[Frontiers in Bioscience 14, 523-539, January 1, 2009]
[Abstract] [Full text] [PDF Type I] [PDF Type II]
[Order reprint Ms#:3260] [Help] [PubMed No] [DOI No:10.2741/3260]
[Managing Editor: Buyong Ma]

Chemokines and chemokine receptors: an overview
Raffaella Bonecchi, Emanuela Galliera, Elena M. Borroni, Massimiliano M. Corsi, Massimo Locati, Alberto Mantovani

[Frontiers in Bioscience 14, 540-551, January 1, 2009]
[Abstract] [Full text] [PDF Type I] [PDF Type II]
[Order reprint Ms#:3261] [Help] [PubMed No] [DOI No:10.2741/3261]
[Managing Editor: Stephan Segerer]

Methods for quantitation of gene expression
Vigdis Nygaard, Eivind Hovig

[Frontiers in Bioscience 14, 552-569, January 1, 2009]
[Abstract] [Full text] [PDF Type I] [PDF Type II]
[Order reprint Ms#:3262] [Help] [PubMed No] [DOI No:10.2741/3262]
[Managing Editor: Jingfang Ju]

Role of Toll-like receptors in systemic Candida albicans infections
Maria Luisa Gil, Daniel Gozalbo

[Frontiers in Bioscience 14, 570-582, January 1, 2009]
[Abstract] [Full text] [PDF Type I] [PDF Type II]
[Order reprint Ms#:3263] [Help] [PubMed No] [DOI No:10.2741/3263]
[Managing Editor: Nina Ivanovska]

Trail and kidney disease
Corina Lorz, Alberto Benito, Alvaro C. Ucero, Beatriz Santamaría, Alberto Ortiz

[Frontiers in Bioscience 14, 570-582, January 1, 2009]
[Abstract] [Full text] [PDF Type I] [PDF Type II] [Express Open Access]
[Order reprint Ms#:3264] [Help] [PubMed No] [DOI No:10.2741/3264]
[Managing Editor: Corina Lorz]

The role of death receptors in neural injury
Corina Lorz, Huseyin Mehmet

[Frontiers in Bioscience 14, 583-595, January 1, 2009]
[Abstract] [Full text] [PDF Type I] [PDF Type II]
[Order reprint Ms#:3265] [Help] [PubMed No] [DOI No:10.2741/3265]
[Managing Editor: Corina Lorz]

AMPK/SNF1 structure: a menage a trois of energy-sensing
John W Scott, Jonathan S Oakhill, Bryce JW van Denderen

[Frontiers in Bioscience 14, 596-610, January 1, 2009]
[Abstract] [Full text] [PDF Type I] [PDF Type II] [Express Open Access]
[Order reprint Ms#:3266] [Help] [PubMed No] [DOI No:10.2741/3266]
[Managing Editor: Lance Macaulay]

Bone marrow transplantation as a strategy for tolerance induction in the clinic
Ines Pree ;, Nina Pilat, Thomas Wekerle

[Frontiers in Bioscience 14, 611-620, January 1, 2009]
[Abstract] [Full text] [PDF Type I] [PDF Type II]
[Order reprint Ms#:3267] [Help] [PubMed No] [DOI No:10.2741/3267]
[Managing Editor: Frank Dor]

Assembly and function of the natural killer cell immune synapse
Pedro Roda-Navarro

[Frontiers in Bioscience 14, 621-633, January 1, 2009]
[Abstract] [Full text] [PDF Type I] [PDF Type II]
[Order reprint Ms#:3268] [Help] [PubMed No] [DOI No:10.2741/3268]
[Managing Editor: Pedro Roda-Navarro]

Chaperone-like effects of cell-permeant ligands on opioid receptors
Yong Chen, Lee-Yuan Liu-Chen

[Frontiers in Bioscience 14, 634-643, January 1, 2009]
[Abstract] [Full text] [PDF Type I] [PDF Type II]
[Order reprint Ms#:3269] [Help] [PubMed No] [DOI No:10.2741/3269]
[Managing Editor: Yingxian Pan]

Interferon signalling in pancreatic beta cells
Helen E Thomas, Kate L Graham, Eveline Angstetra, Mark D McKenzie, Nadine L Dudek, Thomas W Kay

[Frontiers in Bioscience 14, 644-656, January 1, 2009]
[Abstract] [Full text] [PDF Type I] [PDF Type II]
[Order reprint Ms#:3270] [Help] [PubMed No] [DOI No:10.2741/3270]
[Managing Editor: Myung-Shik Lee]

Recent progress in research on beta-cell apoptosis by cytokines
Kyoung-Ah Kim, Myung-Shik Lee

[Frontiers in Bioscience 14, 657-664, January 1, 2009]
[Abstract] [Full text] [PDF Type I] [PDF Type II]
[Order reprint Ms#:3271] [Help] [PubMed No] [DOI No:10.2741/3271]
[Managing Editor: Myung-Shik Lee]

Enhancing oxygen solubility using hemoglobin- and perfluorocarbon-based carriers
Valerie Centis, Patrick Vermette

[Frontiers in Bioscience 14, 665-688, January 1, 2009]
[Abstract] [Full text] [PDF Type I] [PDF Type II]
[Order reprint Ms#:3272] [Help] [PubMed No] [DOI No:10.2741/3272]
[Managing Editor: Patrick Vermette]

Vascular changes after cardiac surgery: role of NOS, COX, kinases, and growth factors
Neel R. Sodha, Richard T. Clements, Frank W. Sellke

[Frontiers in Bioscience 14, 689-698, January 1, 2009]
[Abstract] [Full text] [PDF Type I] [PDF Type II]
[Order reprint Ms#:3273] [Help] [PubMed No] [DOI No:10.2741/3273]
[Managing Editor: Pal Pacher]

Activation of MMP-2 as a key event in oxidative stress injury to the heart
Mohammad A.M. Ali, Richard Schulz

[Frontiers in Bioscience 14, 699-716, January 1, 2009]
[Abstract] [Full text] [PDF Type I] [PDF Type II]
[Order reprint Ms#:3274] [Help] [PubMed No] [DOI No:10.2741/3274]
[Managing Editor: Pal Pacher]

Regulation of epithelial junctions by proteins of the ADP-ribosylation factor family
Toyoko Hiroi

[Frontiers in Bioscience 14, 717-730, January 1, 2009]
[Abstract] [Full text] [PDF Type I] [PDF Type II]
[Order reprint Ms#:3275] [Help] [PubMed No] [DOI No:10.2741/3275]
[Managing Editor: Andrei I. Ivanov]

Virus interaction with the apical junctional complex
Lorenza Gonzalez-Mariscal, Erika Garay, Susana Lechuga

[Frontiers in Bioscience 14, 731-768, January 1, 2009]
[Abstract] [Full text] [PDF Type I] [PDF Type II]
[Order reprint Ms#:3276] [Help] [PubMed No] [DOI No:10.2741/3276]
[Managing Editor: Andrei I. Ivanov]

Neural interactions with materials
Paul Donald Dalton, Joerg Mey

[Frontiers in Bioscience 14, 769-795, January 1, 2009]
[Abstract] [Full text] [PDF Type I] [PDF Type II]
[Order reprint Ms#:3277] [Help] [PubMed No] [DOI No:10.2741/3277]
[Managing Editor: Patrick Vermette]

VOLUME 14, JANUARY 1, 2009, ISSUE 3, PAGES 796-1196

Harnessing human CD1d restricted T cells for tumor immunity: progress and challenges
Madhav V. Dhodapkar

[Frontiers in Bioscience 14, 796-807, January 1, 2009]
[Abstract] [Full text] [PDF Type I] [PDF Type II]
[Order reprint Ms#:3278] [Help] [PubMed No] [DOI No:10.2741/3278]
[Managing Editor: Shin-ichiro Fujii]

The divergence and interplay between pDC and mDC in humans
Norimitsu Kadowaki

[Frontiers in Bioscience 14, 808-817, January 1, 2009]
[Abstract] [Full text] [PDF Type I] [PDF Type II]
[Order reprint Ms#:3279] [Help] [PubMed No] [DOI No:10.2741/3279]
[Managing Editor: Shin-ichiro Fujii]

Immunotherapy for cancer: promoting innate immunity
Ramin Lotfi, Hubert Schrezenmeier, Michael Thomas Lotze

[Frontiers in Bioscience 14, 818-832, January 1, 2009]
[Abstract] [Full text] [PDF Type I] [PDF Type II]
[Order reprint Ms#:3280] [Help] [PubMed No] [DOI No:10.2741/3280]
[Managing Editor: Shin-ichiro Fujii]

Diversity of polyproline recognition by EVH1 domains
Francis C. Peterson, Brian F. Volkman

[Frontiers in Bioscience 14, 833-846, January 1, 2009]
[Abstract] [Full text] [PDF Type I] [PDF Type II]
[Order reprint Ms#:3281] [Help] [PubMed No] [DOI No:10.2741/3281]
[Managing Editor: Martin Schiller]

Post-transcriptional gene regulation by MAP kinases via AU-rich elements
Andrew Clark, Jonathan Dean, Corina Tudor, Jeremy Saklatvala

[Frontiers in Bioscience 14, 847-871, January 1, 2009]
[Abstract] [Full text] [PDF Type I] [PDF Type II]
[Order reprint Ms#:3282] [Help] [PubMed No] [DOI No:10.2741/3282]
[Managing Editor: Matthias Gaestel]

Radiolabelled RGD peptides and peptidomimetics for tumour targeting
Roland Haubner, Clemens Decristoforo

[Frontiers in Bioscience 14, 872-886, January 1, 2009]
[Abstract] [Full text] [PDF Type I] [PDF Type II]
[Order reprint Ms#:3283] [Help] [PubMed No] [DOI No:10.2741/3283]
[Managing Editor: Xinjie Lu]

Application of RGD-containing peptides as imaging probes for alphavbeta3 expression
Ingrid Dijkgraaf, Ambros J. Beer, Hans-Jurgen Wester

[Frontiers in Bioscience 14, 887-899, January 1, 2009]
[Abstract] [Full text] [PDF Type I] [PDF Type II]
[Order reprint Ms#:3284] [Help] [PubMed No] [DOI No:10.2741/3284]
[Managing Editor: Xinjii Liu]

Evolutionary and biophysical relationships among the papillomavirus E2 proteins
Dukagjin M. Blakaj, Narcis Fernandez-Fuentes, Zigui Chen, Rashmi Hegde, Andras Fiser, Robert D. Burk, Michael Brenowitz

[Frontiers in Bioscience 14, 900-917, January 1, 2009]
[Abstract] [Full text] [PDF Type I] [PDF Type II]
[Order reprint Ms#:3285] [Help] [PubMed No] [DOI No:10.2741/3285]
[Managing Editor: Rashmi Hegde]

Genetics, cellular biology and tumor microenvironment of melanoma
Sydney Ch'ng, Swee Thong Tan

[Frontiers in Bioscience 14, 918-928, January 1, 2009]
[Abstract] [Full text] [PDF Type I] [PDF Type II]
[Order reprint Ms#:3286] [Help] [PubMed No] [DOI No:10.2741/3286]
[Managing Editor: Stefania Staibano]

Ectoenzymes and innate immunity: the role of human CD157 in leukocyte trafficking
Ada Funaro, Erika Ortolan, Paola Bovino, Nicola Lo Buono, Giulia Nacci, Rossella Parrotta, Enza Ferrero, Fabio Malavasi

[Frontiers in Bioscience 14, 929-943, January 1, 2009]
[Abstract] [Full text] [PDF Type I] [PDF Type II] [Express Open Access]
[Order reprint Ms#:3287] [Help] [PubMed No] [DOI No:10.2741/3287]
[Managing Editor: Ying-Fu Chen]

Cannabinoid Receptors: A brief history and "what's hot".
Euan Scott Graham, John Clive Ashton, Michelle Glass

[Frontiers in Bioscience 14, 944-957, January 1, 2009]
[Abstract] [Full text] [PDF Type I] [PDF Type II]
[Order reprint Ms#:3288] [Help] [PubMed No] [DOI No:10.2741/3288]
[Managing Editor: Kevin D G Pfleger]

The angiotensin II type 2 (AT2) receptor: an enigmatic seven transmembrane receptor
Enzo R. Porrello, Lea M.D. Delbridge, Walter G. Thomas
[Frontiers in Bioscience 14, 958-972, January 1, 2009]
[Abstract] [Full text] [PDF Type I] [PDF Type II]
[Order reprint Ms#:3289] [Help] [PubMed No] [DOI No:10.2741/3289]
[Managing Editor: Kevin DG Pfleger]

Targeting of G protein-coupled receptors to the plasma membrane in health and disease
Alfredo Ulloa-Aguirre, P. Michael Conn

[Frontiers in Bioscience 14, 973-994, January 1, 2009]
[Abstract] [Full text] [PDF Type I] [PDF Type II]
[Order reprint Ms#:3290] [Help] [PubMed No] [DOI No:10.2741/3290]
[Managing Editor: Kevin DG Pfleger]

Peroxisome proliferator-activated receptors and renal diseases
Jing Wu, Lihong Chen, Dongjuan Zhang, Ming Huo, Xiaoyan Zhang, Dan Pu, Youfei Guan

[Frontiers in Bioscience 14, 995-1009, January 1, 2009]
[Abstract] [Full text] [PDF Type I] [PDF Type II]
[Order reprint Ms#:3291] [Help] [PubMed No] [DOI No:10.2741/3291]
[Managing Editor: Youhua Liu]

SH2 domain binding to phosphopeptide ligands: potential for drug targeting
Moses M. Kasembeli, Xuejun Xu, David J. Tweardy

[Frontiers in Bioscience 14, 1010-1022, January 1, 2009]
[Abstract] [Full text] [PDF Type I] [PDF Type II]
[Order reprint Ms#:3292] [Help] [PubMed No] [DOI No:10.2741/3292]
[Managing Editor: Martin Schiller]

Bone cells-biomaterials interactions
Marie-Eve Marquis, Etienne Lord, Eric Bergeron, Olivier Drevelle, Hyunjin Park, Francois Cabana, Helena Senta, Nathalie Faucheux

[Frontiers in Bioscience 14, 1023-1067, January 1, 2009]
[Abstract] [Full text] [PDF Type I] [PDF Type II]
[Order reprint Ms#:3293] [Help] [PubMed No] [DOI No:10.2741/3293]
[Managing Editor: Patrick Vermette]

Specification of the germ cell lineage in mice
Mitinori Saitou

[Frontiers in Bioscience 14, 1068-1087, January 1, 2009]
[Abstract] [Full text] [PDF Type I] [PDF Type II] [[PDF Type II-Open Access]
[Order reprint Ms#:3294] [Help] [PubMed No] [DOI No:10.2741/3294]
[Managing Editor: Rabindranath De La Fuente]

Epithelial cell surface polarity: the early steps
Lene N. Nejsum, W. James Nelson

[Frontiers in Bioscience 14, 1088-1098, January 1, 2009]
[Abstract] [Full text] [PDF Type I] [PDF Type II]
[Order reprint Ms#:3295] [Help] [PubMed No] [DOI No:10.2741/3295]
[Managing Editor: Andrei I. Ivanov]

Failure of beta-cell adaptation in type 2 diabetes: Lessons from animal models
Nurit Kaiser, Gil Leibowitz

[Frontiers in Bioscience 14, 1099-1115, January 1, 2009]
[Abstract] [Full text] [PDF Type I] [PDF Type II]
[Order reprint Ms#:3296] [Help] [PubMed No] [DOI No:10.2741/3296]
[Managing Editor: Frédéric De Ceuninck]

Parthanatos, a messenger of death
Karen Kate David, Shaida Ahmad Andrabi, Ted Murray Dawson, Valina Lynn Dawson

[Frontiers in Bioscience 14, 1116-1128, January 1, 2009]
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[Order reprint Ms#:3297] [Help] [PubMed No] [DOI No:10.2741/3297]
[Managing Editor: Pal Pacher]

Regulation of epithelial apical junctional complex by Rho family GTPases
Stanislav Samarin, Asma Nusrat

[Frontiers in Bioscience 14, 1129-1142, January 1, 2009]
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[Order reprint Ms#:3298] [Help] [PubMed No] [DOI No:10.2741/3298]
[Managing Editor: Andrei I. Ivanov]

Structural conservation of a short, functional, peptide-sequence motif
Susan Fox-Erlich, Martin R. Schiller, Michael R. Gryk

[Frontiers in Bioscience 14, 1143-1151, January 1, 2009]
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[Order reprint Ms#:3299] [Help] [PubMed No] [DOI No:10.2741/3299]
[Managing Editor: Martin R. Schiller]

Role of resident CNS cell populations in HTLV-1-associated neuroinflammatory disease
Veronique Lepoutre, Pooja Jain, Kevin Quann, Brian Wigdahl, Zafar K. Khan

[Frontiers in Bioscience 14, 1152-1168, January 1, 2009]
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[Order reprint Ms#:3300] [Help] [PubMed No] [DOI No:10.2741/3300]
[Managing Editor: Muhammad Mukhtar]

Current strategies for the inhibition of hepatic glucose production in type 2 diabetes
Dale S. Edgerton, Kathryn M. S. Johnson, Alan D. Cherrington

[Frontiers in Bioscience 14, 1169-1181, January 1, 2009]
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[Order reprint Ms#:3301] [Help] [PubMed No] [DOI No:10.2741/3301]
[Managing Editor: Frédéric De Ceuninck]

PML nuclear bodies and their spatial relationships in the mammalian cell nucleus
Elizabeth Batty, Kirsten Jensen, Paul FreemontPaul Freemont

[Frontiers in Bioscience 14, 1182-1196, January 1, 2009]
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[Order reprint Ms#:3302] [Help] [PubMed No] [DOI No:10.2741/3302]
[Managing Editor: Katherine L.B. Borden]

VOLUME 14, JANUARY 1, 2009, ISSUE 4, PAGES 1197-1595

Crosstalk signaling between mitochondrial Ca2+ and ROS
Robert F. Feissner, Jolanta Skalska, Winston E. Gaum, Shey-Shing Sheu

[Frontiers in Bioscience 14, 1197-1218, January 1, 2009]
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[Order reprint Ms#:3303] [Help] [PubMed No] [DOI No:10.2741/3303]
[Managing Editor: Rosana A. Bassani]

SUMO conjugation and cardiovascular development
Jun Wang

[Frontiers in Bioscience 14, 1219-1229, January 1, 2009]
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[Order reprint Ms#:3304] [Help] [PubMed No] [DOI No:10.2741/3304]
[Managing Editor: Avadhesh C. Sharma]

Macrophage antioxidant protection within atherosclerotic plaques
Steven P. Gieseg, David S. Leake, Elizabeth M. Flavall, Zunika Amit, Linzi Reid, Ya-Ting Yang

[Frontiers in Bioscience 14, 1230-1246, January 1, 2009]
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[Order reprint Ms#:3305] [Help] [PubMed No] [DOI No:10.2741/3305]
[Managing Editor: Andrea I. Doseff]

The evolution of vertebrate opioid receptors
Craig W. Stevens

[Frontiers in Bioscience 14, 1247-1269, January 1, 2009]
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[Order reprint Ms#:3306] [Help] [PubMed No] [DOI No:10.2741/3306]
[Managing Editor: Yingxian Pan]

Regulation of bovine papillomavirus type 1 gene expression by RNA processing
Rong Jia, Zhi-Ming Zheng

[Frontiers in Bioscience 14, 1270-1282, January 1, 2009]
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[Order reprint Ms#:3307] [Help] [PubMed No] [DOI No:10.2741/3307]
[Managing Editor: Zhi-Ming Zheng]

Water transport in aquaporins: molecular dynamics simulations
Mitsunori Ikeguchi

[Frontiers in Bioscience 14, 1283-1291, January 1, 2009]
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[Order reprint Ms#:3308] [Help] [PubMed No] [DOI No:10.2741/3308]
[Managing Editor: Masahiro Kinoshita]

Free-energy landscapes of proteins in solution by generalized-ensemble simulations
Yuji Sugita

[Frontiers in Bioscience 14, 1292-1303, January 1, 2009]
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[Order reprint Ms#:3309] [Help] [PubMed No] [DOI No:10.2741/3309]
[Managing Editor: Masahiro Kinoshita]

Archaeal chaperonins
Andrew T. Large, Peter A. Lund

[Frontiers in Bioscience 14, 1304-1324, January 1, 2009]
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[Order reprint Ms#:3310] [Help] [PubMed No] [DOI No:10.2741/3310]
[Managing Editor: Alberto J. L. Macario]

PML nuclear bodies as sites of epigenetic regulation
Dora Torok, Reagan W. Ching, David P. Bazett-Jones

[Frontiers in Bioscience 14, 1325-1336, January 1, 2009]
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[Order reprint Ms#:3311] [Help] [PubMed No] [DOI No:10.2741/3311]
[Managing Editor: Katherine Borden]

Biochemical properties of plasminogen activator inhibitor-1
Daniel Miotto Dupont, Jeppe Buur Madsen, Thomas Kristensen, Julie Stove Bodker, Grant Ellsworth Blouse, Troels Wind, Peter Andre Andreasen

[Frontiers in Bioscience 14, 1337-1361, January 1, 2009]
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[Order reprint Ms#:3312] [Help] [PubMed No] [DOI No:10.2741/3312]
[Managing Editor: Pia Ragno]

Genomic features of Lactobacillus species
Yong Jun Goh, Todd R. Klaenhammer

[Frontiers in Bioscience 14, 1362-1386, January 1, 2009]
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[Order reprint Ms#:3313] [Help] [PubMed No] [DOI No:10.2741/3313]
[Managing Editor: Marco Ventura]

Roles of water in protein structure and function studied by molecular liquid theory
Takashi Imai

[Frontiers in Bioscience 14, 1387-1402, January 1, 2009]
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[Order reprint Ms#:3314] [Help] [PubMed No] [DOI No:10.2741/3314]
[Managing Editor: Masahiro Kinoshita]

RAGE signaling in inflammation and arterial aging
Li Lin, Sungha Park, Edward G. Lakatta

[Frontiers in Bioscience 14, 1403-1413, January 1, 2009]
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[Order reprint Ms#:3315] [Help] [PubMed No] [DOI No:10.2741/3315]
[Managing Editor: FBS]

The assembly and maintenance of epithelial junctions in C. elegans
Allison M. Lynch, Jeff Hardin

[Frontiers in Bioscience 14, 1414-1432, January 1, 2009]
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[Order reprint Ms#:3316] [Help] [PubMed No] [DOI No:10.2741/3316]
[Managing Editor: Andrei I. Ivanov]

Adult stem cells and repair through granulation tissue
Lucio Diaz-Flores Jr., Ricardo Gutierrez, Juan Francisco Madrid, Hilda Varela, Francisco Valladares, Lucio Diaz-Flores

[Frontiers in Bioscience 14, 1433-1470, January 1, 2009]
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[Order reprint Ms#:3317] [Help] [PubMed No] [DOI No:10.2741/3317]
[Managing Editor: Shree R. Singh]

Genetic cell culture screens reveal mitochondrial apoptosis control
Stefan Grimm, Bevan Lin

[Frontiers in Bioscience 14, 1471-1478, January 1, 2009]
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[Order reprint Ms#:3318] [Help] [PubMed No] [DOI No:10.2741/3318]
[Managing Editor: Catherine Brenner-Jan]

Cell signaling modifiers for molecular targeted therapy in ATLL
Naoki Mori

[Frontiers in Bioscience 14, 1479-1489, January 1, 2009]
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[Order reprint Ms#:3319] [Help] [PubMed No] [DOI No:10.2741/3319]
[Managing Editor: Franco Buonaguro]

Helicobacter Pylori associated global gastric cancer burden
Sam M. Mbulaiteye, Michie Hisada, Emad M. El-Omar

[Frontiers in Bioscience 14, 1490-1504, January 1, 2009]
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[Order reprint Ms#:3320] [Help] [PubMed No] [DOI No:10.2741/3320]
[Managing Editor: Franco Buonaguro]

Proteomics of tendinopathy
Mary T Johnson

[Frontiers in Bioscience 14, 1505-1515, January 1, 2009]
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[Order reprint Ms#:3321] [Help] [PubMed No] [DOI No:10.2741/3321]
[Managing Editor: Nicola Maffulli]

Kaposi's sarcoma-associated herpesvirus ORF57 in viral RNA processing
Vladimir Majerciak, Zhi-Ming Zheng

[Frontiers in Bioscience 14, 1516-1528, January 1, 2009]
[Abstract] [Full text] [PDF Type I] [PDF Type II] [Express Open Access]
[Order reprint Ms#:3322] [Help] [PubMed No] [DOI No:10.2741/3322]
[Managing Editor: Zhi-Ming Zheng]

Key players in chromosome segregation in Caenorhabditis elegans
Risa Kitagawa

[Frontiers in Bioscience 14, 1529-1557, January 1, 2009]
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[Order reprint Ms#:3323] [Help] [PubMed No] [DOI No:10.2741/3323]
[Managing Editor: Katsumi Kitagawa]

GSK-3 inhibitors and insulin receptor signaling in health, disease, and therapeutics
Akihiko Wada

[Frontiers in Bioscience 14, 1558-1570, January 1, 2009]
[Abstract] [Full text] [PDF Type I] [PDF Type II] [Express Open Access]
[Order reprint Ms#:3324] [Help] [PubMed No] [DOI No:10.2741/3324]
[Managing Editor: Akihiko Wada]

Extracellular matrix proteases - cytokine regulation role in cancer and pregnancy
Bor-Ching Sheu, Wen-Chun Chang, Chieh-Yang Cheng, Peng-Hui Wang, Shiming Lin, Su-Cheng Huang

[Frontiers in Bioscience 14, 1571-1588, January 1, 2009]
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[Order reprint Ms#:3325] [Help] [PubMed No] [DOI No:10.2741/3325]
[Managing Editor: Lukasz Wicherek]

Activation of dendritic cells by polymorphonuclear neutrophils
Sarah Boudaly

[Frontiers in Bioscience 14, 1589-1595, January 1, 2009]
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[Order reprint Ms#:3326] [Help] [PubMed No] [DOI No:10.2741/3326]
[Managing Editor: Oliver Soehnlein]

VOLUME 14, JANUARY 1, 2009, ISSUE 5, PAGES 1596-1989

Mechanisms of neutrophil transendothelial migration
Eun Young Choi, Sentot Santoso, Triantafyllos Chavakis

[Frontiers in Bioscience 14, 1596-1605, January 1, 2009]
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[Order reprint Ms#:3327] [Help] [PubMed No] [DOI No:10.2741/3327]
[Managing Editor: Oliver Soehnlein]

RNA-protein interactions in hepadnavirus reverse transcription
Jianming Hu, Li Lin

[Frontiers in Bioscience 14, 1606-1618, January 1, 2009]
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[Order reprint Ms#:3328] [Help] [PubMed No] [DOI No:10.2741/3328]
[Managing Editor: Xiaofeng Charles Zhou]

Poly (ADP-ribose) glycohydrolase (PARG) and its therapeutic potential
WooKee Min, Zhao-Qi Wang

[Frontiers in Bioscience 14, 1619-1626, January 1, 2009]
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[Order reprint Ms#:3329] [Help] [PubMed No] [DOI No:10.2741/3329]
[Managing Editor: Michael O. Hottiger]

Immunosuppression for lung transplantation
Choo Y. Ng, Joren C. Madsen, Bruce R. Rosengard, James S. Allan

[Frontiers in Bioscience 14, 1627-1641, January 1, 2009]
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[Order reprint Ms#:3330] [Help] [PubMed No] [DOI No:10.2741/3330]
[Managing Editor: Frank Dor]

Can we prevent parkinson's disease?
Christine R. Swanson, Samantha L. Sesso, Marina E. Emborg

[Frontiers in Bioscience 14, 1642-1660, January 1, 2009]
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[Order reprint Ms#:3331] [Help] [PubMed No] [DOI No:10.2741/3331]
[Managing Editor: Marina E. Emborg]

Bacteriophages of Lactobacillus
Manuela Villion, Sylvain Moineau

[Frontiers in Bioscience 14, 1661-1683, January 1, 2009]
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[Order reprint Ms#:3332] [Help] [PubMed No] [DOI No:10.2741/3332]
[Managing Editor: Marco Ventura]

PML nuclear bodies in the pathogenesis of acute promyelocytic leukemia: active players or innocent bystanders?
Nicola J.M. Brown, Michal Ramalho, Eva W. Pedersen, Eva Moravcsik, Ellen Solomon, David Grimwade

[Frontiers in Bioscience 14, 1684-1707, January 1, 2009]
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[Order reprint Ms#:3333] [Help] [PubMed No] [DOI No:10.2741/3333]
[Managing Editor: Katherine L.B. Borden]

Pathogenesis and therapy of autoimmunity-induced dilated cardiomyopathy
Peng Zhao, Avadhesh C. Sharma, Jun Ren

[Frontiers in Bioscience 14, 1708-1715, January 1, 2009]
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[Order reprint Ms#:3334] [Help]