[Frontiers in Bioscience 1, a59-68, 4 October 1996]
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CAVEAT LECTOR



DELETION OF THE HERPES SIMPLEX VIRUS 1 INTERNAL REPEAT SEQUENCES AFFECTS PATHOGENICITY IN THE MOUSE

Frank J. Jenkins1, Alyson M. Donoghue2 and John R. Martin3

1 Department of Pathology and Infectious Diseases and Microbiology, University of Pittsburgh, and Division of Behavioral Medicine, University of Pittsburgh Cancer Institute, Pittsburgh, PA 15213
2 Department of Microbiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, MD. 20814
3 Food and Drug Administration, Division of Antiviral Drug Products, Rockville, MD 20857.

Received 07/30/96; Accepted 08/27/96; On-line 10/04/96

TABLE OF CONTENTS

1. Abstract
2. Introduction
3. Methods
4. Results
5. Discussion
6. Acknowledgments
7. References
8. Entire manuscript
Key Words: Herpes Simplex Virus, Pathogenicity, Neurovirulence, Neuroinvasiveness, Latency, Deletion Mutants