Ned J.C.Lamb, Cecile Gauthier-Rouviere and Anne Fernandez.

Cell Biology Unit, C R B M , CNRS-INSERM, 1919, Route de Mende, F-34033, Montpellier Cedex. France.

Received 15/12/95; Accepted 30/01/96; On-line 03/01/96

REFERENCES

1. Greenberg, M.E., & E.B. Ziff: Stimulation of 3T3 cells induces transcription of c-fos proto-oncogene. Nature, 311, 433-438, (1984)

2. Muller, R., Bravo, R., Burckhartdt, J. & T. Curran: Induction of c-fos gene and protein by growth factors precedes activation of c-myc. Nature, 312, 716-720.(1984)

3. Bravo, R.H., Burckhart, J., Curran, T. & R. Muller: Expression of c-fos in NIH/3T3 cells is very low but inducible throughout the cell cycle. EMBO J, 5, 695-700.(1986)

4. R. Bravo: Genes induced during the G0/G1 transition in mouse fibroblasts. Seminars in Cancer Research, 1, 37-46.(1990)

5. Riabowol, K.T., Vosatka, R.J., Ziff, E.B., Lamb, N.J. & J.R. Feramisco: Microinjection of fos-specific antibodies blocks DNA synthesis in fibroblasts cells. Mol Cell Biol , 8, 1670-1676.(1988)

6. Gilman, M.Z., Wilson, R.N. & R.A. Weinberg: Multiple protein binding sites in the 5'-flanking region regulate c-fos expression. Mol Cell Biol, 6 4305-4316.(1986)

7. Treisman, R.: Identification of a protein-binding site that mediates transcriptional response of the c-fos gene to serum factors. Cell, 46, 567-574.(1986)

8. Prywes, R. & R.G. Roeder: Purification of the c-fos enhancer binding protein. Mol Cell Biol, 7, 3482-3489.(1987)

9. Treisman, R.: Identification and purification of a polypeptide that binds to the c-fos serum response element. EMBO J, 6, 2711-2717. (1987)

10. Norman, C., Runswick, M., Pollock, R. & R. Treisman: Isolation and properties of cDNA clones encoding SRF, a transcription factor that binds to the c-fos serum response element. Cell, 55, 989-1003. (1988)

11. Treisman R.: The serum response element. Trends Biol Sci 17, 423-426. (1992)

12. Gauthier-Rouvière, C., Fernandez, A. & N.J.C. Lamb: Ras induced c-fos expression and proliferation in living rat fibroblasts involves c-kinase activation and serum response element pathway. EMBO J, 9, 171-180.(1990)

13. Lamb, N.J.C., Fernandez, A., Tourkine, N., Jeanteur, P. & J-M. Blanchard: Demonstration in living cells of an intragenic negative regulatory element within the rodent c-fos gene. Cell, 61, 485-496.(1990)

14. Berkowitz, L.A., Riabowol, K.T. & M.Z. Gilman: Multiple sequence elements of a single functional class are required for cyclic AMP responsiveness of the mouse c-fos promoter. Mol Cell Biol 9, 4272-81.(1989)

15. Gauthier-Rouvière, C., Basset, M., Blanchard, J.M., Cavadore, J.C., Fernandez, A. & N.J.C. Lamb: Casein kinase II induces c-fos expression via the serum response element pathway and p67SRF phosphorylation in living fibroblasts. EMBO J., 10, 2921-2930.(1991)

16. Gauthier-Rouvière, C., Cavadore, J.C., Blanchard, J.M., Lamb, N.J.C. & A. Fernandez: p67SRF is a constitutive nuclear protein implicated in the modulation of genes required throughout the G1 period. Cell Reg, 2, 575-588.(1991)

17. Vandromme, M. , Gauthier-Rouvière, C., Carnac, G., Lamb, N. & A. Fernandez: Serum response factor p67SRF is expressed and required during myogenic differentiation of both mouse C2 and rat L6 muscle cell lines. (1992) J Cell Biol, 6, 1489-1500.(1992)

18. Gauthier-Rouvière, C., Caï, Q.Q., Lautredou, N., Fernandez, A., Blanchard, J.M. & N.J.C. Lamb: Expression and purification of the DNA binding domain of SRF : SRF-DB, a part of a DNA binding protein which can act as a dominant negative mutant in vivo. Exp Cell Res, 209, 208-215. (1993)

19. Greenberg, M.E., Hermanowski, A.L. & E.B. Ziff: Effects of protein synthesis inhibitors on growth factor activation of c-fos, c-myc and actin gene transcription. Mol Cell Biol, 6, 1050-1057. (1986)

20. Gauthier-Rouviere, C. , M. Basset, M., N.J.C. Lamb. & A. Fernandez: Role of fos-AP-1 binding sequence (FAP) in the induction of c-fos expression by purified C-kinase and in c-fos down regulation following serum induction. Oncogene, 7, 363-369. (1992)

21. Manack, J.R. & R. Prywes: Casein kinase II enhances the DNA binding factors activity of serum response factor. Mol Cell Biol, 11, 3652-3659.(1991)

22. Marais, R.M., Hsuan, J.J., McGuigan, C., Wynne, J. & R. Treisman: Casein kinase II phosphorylation increases the rate of serum response factor-binding site exchange. EMBO J, 11, 97-105. (1992)

23. A.S. Alberts, T. Deng, A. Lin, J.L. Meinkoth, A. Schonthal, M.C. Mumby, M. Karin & J.R. Feramisco: Protein phosphatase 2A potentiates activity of promoters containing AP-1-binding elements. Mol. Cell. Biol. 13, 2104-12. (1993)

24. Fernandez, A., Mery, J., Vandromme, M., Basset, M., Cavadore, J.C. & N.J.C. Lamb: Effective intracellular inhibition of the cAMP-dependent protein kinase activity by microinjection of a modified form of the specific inhibitory peptide PKI in living fibroblasts. Exp Cell Res, 195, 468-477.(1991)

25. House, C. & B.E. Kemp: Protein kinase C contains a pseudosubstrate prototrope in its regulatory domain. Science, 238, 1726-1728, (1987)

26. Lamb, N.J.C., Labbé, J-C., Maurer, R. and A. Fernandez: .Inhibition of cAMP-dependent protein kinase plays a key role in the induction of mitosis and nuclear envelope breakdown in mammalian cells. EMBO J, 10: 1523-1533. (1991)

27. Fernandez, A., Cavadore, J.C., Demaille, J. & N.J.C. Lamb: Implication for cAMP-dependent protein kinase in the maintenance of the interphase state. In Progress Cell Cycle Res 1, 241-253. (1995)

28. Gauthier-Rouvière, C., Vandromme, M., Lautredou, N., Caï, Q.Q., Girard, F., Fernandez, A. & N.J.C. Lamb: The SRF nuclear localization signal : general implication for cAMP-dependent protein kinase activity in the control of the nuclear translocation. Mol Cell Biol, 15, 433-444.(1995)

29. A.S. Alberts, M. Montminy, S. Shenolikar & J.R. Feramisco: Expression of a peptide inhibitor of protein phosphatase 1 increases phosphorylation and activity of CREB in NIH 3T3 fibroblasts. Mol Cell Biol 14, 4398-407. (1994)

30. Boulton, T.G., S.H.Nye, D.J. Robbins, N.Y Ip, S.D.Radziejewska, R.A.Morgenbesser, R.A.DePinho, N. Panayotatos, M.H.Cobbs, & G.D.Yancopoulos: ERKs: a family of protein-serine/threonine kinases that are activated and tyrosine phosphorylated in response to insulin and NGF. Cell, 65, 663-675.(1991)

31. Girard, F., Strausfeld, U., Fernandez, A. & N.J.C. Lamb: Cyclin A is required for the onset of DNA replication in mammalian fibroblasts. Cell, 67, 1169-1179.(1991)