Yasuhito Abe, M.D.

The Second Department of Surgery, Ehime University School of Medicine, Shigenobu, Ehime 791-02, Japan

Received 05/15/96; Accepted 06/12/96; On-line 07/01/96

Natural human immunoglobulin for intra-venous administration has been proven to be effective for treatment of some disorders. Although in view of its limited side effects, this preparation is being widely used, the cost and benefit of its use should be carefully examined and specific guidelines for its use should be established.