[Frontiers in Bioscience 1, e87-95, September 1,1996]
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CAVEAT LECTOR



APPLICATION OF SPERM ANTIGENS IN IMMUNOCONTRACEPTION

Rajesh K. Naz

Division of Research, Department of Obstetrics and Gynecology, Medical College of Ohio, Toledo, Ohio 43699, USA

Received 07/23/96; Accepted 07/30/96; On-line 09/01/96

TABLE OF CONTENTS

1. Abstract
2. Introduction
3. Discussion
3.1 Rationale and feasibility
3.2 Sperm antigens that have been proposed as candidates for immunocontraception
3.2.1 Lactate dehydrogenase (LDH) C4
3.2.2 Rabbit sperm autoantigens (RSA) family
3.2.3 PH-20 antigen
3.2.4 SP-10 antigen
3.2.5 HSA-63 antigen
3.2.6 Fertilization antigen-1 (FA-1)
3.2.7 FA-2 antigen
3.2.8 Cleavage signal protein (CS-1)
3.3 Increasing the immunogenicity of anti-sperm contraceptive vaccines
4. Conclusions
5. Acknowledgments
6. References
7. Entire manuscript

Key Words: sperm antigens/sperm antibodies/sperm/contraception/vaccines