[Frontiers in Bioscience 1, e78-86, August 1,1996]
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PubMed
CAVEAT LECTOR



OXIDATIVE STRESS AND ROLE OF ANTIOXIDANTS IN NORMAL AND ABNORMAL SPERM FUNCTION

Suresh C. Sikka, Ph.D., HCLD

Department of Urology, Tulane University School of Medicine, New Orleans, Louisiana, USA

Received 05/30/96; Accepted 07/02/96; On-line 08/01/96

TABLE OF CONTENTS

1. Abstract
2. Introduction
3. Normal and abnormal sperm function
4. Oxidative stress
4.1 Reactive Oxygen Species and Oxidative Stress
4.2 Spermatozoa and leukocytes as sites of R
4.3 Leukocytospermia and oxidative stress
4.4 Oxidative stress and sperm function
5. Mode of action of RO
5.1 Lipid peroxidation of spermatozoa
5.2 Biological implications of LPO and oxidative stress
6. Antioxidants and oxidatve stress
7. Role of genitourinary inflammation and oxidative stress
8. Aging and oxidative stress
9. Assessment of oxidative stress
9.1 Oxidative stress status evaluation
10. Conclusions
11. References
12. Entire manuscript

Key Words: Reactive oxygen and reactive nitrogen species, membrane peroxidation, antioxidants, sperm motion/function