[Frontiers in Bioscience 1, e1-8, January 1, 1996]
Reprints
PubMed
CAVEAT LECTOR



CORTICOTROPIN RELEASING HORMONE (CRH) IN NORMAL AND PREGNANT UTERUS: PHYSIOLOGICAL IMPLICATIONS

Zoumakis E, Makrigiannakis A, Margioris A, Stournaras C, Gravanis A

Departments of Pharmacology, Clinical Chemistry, Biochemistry, Medical School, University of Crete, Iraklion 71110, Greece
Received 11/2/95; Accepted 12/14/95; On-line1/1/96



3. CRH BINDING PROTEIN

The amount of CRH that is secreted into the blood is probably modulated by a specific circulating CRH-binding protein (CRHBP) (14-16), which is mainly synthesized in the liver and is also expressed in the human brain, playing an important physiological role in CRH availability.

Table 1.
REPRODUCTIVE TISSUES EXPRESSING THE CRH GENE.
MaleTestesLeydig cells, germ cells
FemaleOvariesFollicles, corpora lutea
Pregnant uterusamnion
chorion
syncytiotrophoblast
decidua
non-pregnant uterusglandular endometrium
decidualized stroma


[Table of Contents] [Next Section] [Previous Section]