[Frontiers in Bioscience 2, d298-308, June 15, 1997]
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TRANSGENIC RABBIT MODELS FOR THE STUDY OF ATHEROSCLEROSIS

John M. Taylor and Jianglin Fan

Gladstone Institute of Cardiovascular Disease, the Department of Physiology, and the Cardiovascular Research Institute, University of California, San Francisco, CA

TABLE OF CONTENTS

1. Abstract
2. Introduction
3. Rabbit models for the study of lipid metabolism
4. Rabbit breeding
5. Generating transgenic rabbits
6. Hepatic lipase transgenic rabbits
7. Apolipoprotein E transgenic rabbits
8. Apolipoprotein B transgenic rabbits
9. Apolipoprotein B mRNA-editing protein (APOBEC-1) transgenic rabbits
10. Apolipoprotein A-I transgenic rabbits
11. Lecithin-cholesterol acyl transferase (LCAT) transgenic rabbits
12. Conclusion
13. Acknowledgment
14. References
15. Entire manuscript

Keywords: Atherosclerosis, Cardiovascular system