[Frontiers in Bioscience 2, e108-115, November 1, 1997]
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EFFECT OF AGING AND CALORIC RESTRICTION ON INTESTINAL SUGAR AND AMINO ACID TRANSPORT

Ronaldo P. Ferraris

Dept of Pharmacology and Physiology, UMDNJ-New Jersey Medical School, 185 South Orange Ave., Newark, NJ 07103

Received 7/17/97 Accepted 10/2/97

TABLE OF CONTENTS

1. Abstract
2. Introduction

2.1. Basis for normalization 2.2 Intestinal sugar and amino acid transporters
3. Effect of aging on sugar transport
4. Effect of aging on amino acid transport
5. Proximate mechanisms of age-related decreases in transport rates
5.1. Nonspecific mechanisms
5.2. Specific mechanisms
6. Regulation of intestinal sugar and amino acid transport by diet
7. Effect of caloric restriction on intestinal nutrient transport
8. Perspective
9. Acknowledgments
10. Entire manuscript

Key words: Adaptation, Carbohydrates, Fasting, Intestinal anatomy, Intestinal proliferation, Nutrition, Proteins, Starvation, SLGT1, GLUT5, GLUT2