[Frontiers in Bioscience 2, d3417-426, September 1, 1997]

	[Frontiers in Bioscience 2, d3417-426, September 1, 1997] Reprints PubMed CAVEAT LECTOR
	TRANSCRIPTION FACTORS AND THE DOWN-REGULATION OF G1/S BOUNDARY GENES IN HUMAN DIPLOID FIBROBLASTS DURING SENESCENCE Kuang Yu Chen Department of Chemistry and The Cancer Institute of New Jersey, Rutgers - The State University of New Jersey, Piscataway, NJ. 08855-0939 Received 8/19/97 Accepted 8/25/97 TABLE OF CONTENTS 1. Abstract 2. Introduction 3. Changes of gene expression during senescence 3.1 Global attenuation of G1/S genes 3.2 Molecular basis for the global attenuation of G1/S genes 3.3 Binding activity as measured by gel mobility shift assay 3.4 The regulation of transcription factor activity during senescence 4. Transcriptional binding sites in the G1/S gene promoters 4.1 Promoter analysis of G1/S genes 4.2 Promoter organizations of TK and DHFR genes 4.3 Group 1 G1/S genes with CCAAT repeats within their promoters 4.4 Group 2 G1/S genes with E2F site within their promoters 4.5 Late G1/S genes containing other cis-elements within their promoters 4.6 Promoter analysis of NF-Y, NF-YB and E2F1 5. Perspective and summary 6.Acknowledgments 7. References 8. Entire manuscript Keywords: Search OMIM (Online Mendelian Inheritance in Man) to find related articles This form requires a WWW Client such as Netscape, XMosaic, Lynx that supports fill-in forms. Enter one or more search keywords: To Search all fields, leave the following boxes unchecked. To narrow your search to certain specific fields, check the boxes next to those fields' names. SeeQuery Help for other ways to search. Title: OMIM Number: Allelic Variants: Text: References: Clinical Synopsis: Gene Map Disorder: Contributors: See only records which have been changed in the past Display at most

[Frontiers in Bioscience 2, d3417-426, September 1, 1997]
Reprints
PubMed
CAVEAT LECTOR

TRANSCRIPTION FACTORS AND THE DOWN-REGULATION OF G1/S BOUNDARY GENES IN HUMAN DIPLOID FIBROBLASTS DURING SENESCENCE

Kuang Yu Chen

Department of Chemistry and The Cancer Institute of New Jersey, Rutgers - The State University of New Jersey, Piscataway, NJ. 08855-0939

Received 8/19/97 Accepted 8/25/97

TABLE OF CONTENTS

1. Abstract
2. Introduction
3. Changes of gene expression during senescence: 3.1 Global attenuation of G1/S genes; 3.2 Molecular basis for the global attenuation of G1/S genes; 3.3 Binding activity as measured by gel mobility shift assay; 3.4 The regulation of transcription factor activity during senescence
4. Transcriptional binding sites in the G1/S gene promoters: 4.1 Promoter analysis of G1/S genes; 4.2 Promoter organizations of TK and DHFR genes; 4.3 Group 1 G1/S genes with CCAAT repeats within their promoters; 4.4 Group 2 G1/S genes with E2F site within their promoters; 4.5 Late G1/S genes containing other cis-elements within their promoters; 4.6 Promoter analysis of NF-Y, NF-YB and E2F1
5. Perspective and summary
6.Acknowledgments
7. References
8. Entire manuscript

Keywords:

Search OMIM (Online Mendelian Inheritance in Man) to find related articles
This form requires a WWW Client such as Netscape, XMosaic, Lynx that supports fill-in forms.