[Frontiers in Bioscience 2, d260-270, June 1, 1997]
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MOLECULAR MECHANISM OF ACTIN-DEPENDENT RETROGRADE FLOW IN LAMELLIPODIA OF MOTILE CELLS.

Louise P. Cramer

The Randall Institute, Kings College London, 26-29 Drury Lane, London WC2B 5RL, UK.

Received 5/21/97; Accepted 5/26/97

8. REFERENCES

1. Pasternak, C. Spudich, J. A.& Elson, E. L.: Capping of surface receptors and concomitant cortical tension are generated by conventional myosin. Nature 341, 549-551 (1989).

2. Fukui, Y. De Lozanne, A.& Spudich, J. A.: Structure and function of the cytoskeleton of a Dictyostelium myosin-defective mutant. J. Cell Biol 110, 367-378 (1990).

3. Jay, P. Y.& Elson, E. L.: Surface particle transport mechanism independent of myosin II in Dictyostelium. Nature 356, 438-440 (1992).

4. Heath, J. P.& Holifield, B. F.: Cell locomotion: New research tests old ideas on membrane and cytoskeletal flow. Cell Motil. Cytoskeleton 18, 245-257 (1991).

5. Sheetz, M. P.: Glycoprotein motility and dynamic domains in fluid plasma membranes. Annu. Rev. Biophys. Biomol. Struct. 22, 417-431 (1993).

6. Grebecki, A.: Membrane and cytoskeletal flow in motile cells with emphasis on the contribution of free-living amoeba. Int. Rev. Cytol. 148, 37-79 (1994).

7. Harris, A. K.: Locomotion of tissue culture cells considered in relation to ameboid locomotion. Int. Rev. Cytol. 150, 35-68 (1994).

8. P Forscher, & S J Smith: Cytoplasmic actin filaments move particles on the surface of a neuronal growth cone. In: Optical Microscopy for Biology. Wiley Liss, Inc., New York, 459-471 (1990).

9. Sheetz, M. P. Turney, S. Qian, H.& Elson, E. L.: Nanometre-level analysis demonstrates that lipid-flow does not drive membrane glycoprotein movements. Nature 340, 284-288 (1989).

10. de Brabander, M. Nuydens, R. Ishihara, A. Holifield, B. Jacobson, K.& Geerts, H.: Lateral diffusion and retrograde movements of individual cell surface components on single motile cells observed with Nanovid microscopy. J. Cell Biol. 112, 111-124 (1991).

11. A K Harris: Cell surface movements related to cell locomotion. In: Locomotion of tissue cells. CIBA Foundation Symposium. Eds: Porter R, Fitzsimmons, Elsevier, Amsterdam, 3-26 (1973).

12. Huxley, H. E.: Muscular contraction and cell motility. Nature 243, 445-449 (1973).

13. Singer, S. J.& Nicolson, G. L.: The fluid mosaic model of the structure of cell membranes. Science 175, 720-731 (1972).

14. Mitchison, T. J.& Cramer, L. P.: Actin based cell motility and cell locomotion. Cell 84, 371-379 (1996).

15. Small, J. V. Isneberg, G.& Celis, J. E.: Polarity of actin at the leading edge of cultured cells. Nature (Lond.) 272, 638-639 (1978).

16. Small, J. V.: The actin cytoskeleton. Electron Microsc Rev 1, 155-74 (1988).

17. Lewis, A. K.& Bridgman, P. C.: Nerve growth cone lamellipodia contain two populations of actin filaments that differ in organization and polarity. J. Cell Biol. 119, 1219-1243 (1992).

18. Small, J. V. Herzog, M.& Anderson, K.: Actin filament organization in the fish keratocyte lamellipodium. J. Cell Biol. 129, 1275-1286 (1995).

19. Cramer, L. P. Siebert, M.& Mitchison, T. J.: Identification of novel graded polarity actin filament bundles in locomoting heart fibroblasts: implications for the generation of motile force. J. Cell Biol. 136, 1287-1305 (1997).

20. Wang, Y.-L.: Exchange of actin subunits at the leading edge of living fibroblasts: possible role of treadmilling. J. Cell. Biol. 101, 597-602 (1985).

21. Svitkina, T. M. Neyfakh, A. A.& Bershadsky, A.: Actin cytoskeleton of spread fibroblasts appears to assemble at the cell edge. J. Cell Sci. 82, 235-248 (1986).

22. Okabe, R.& Hirokawa, N.: Incorporation and turnover of biotin-labeled actin microinjected into fibroblastic cells: An immunoelectron microscopic study. J. Cell Biol. 109, 1581-1595 (1989).

23. Symons, M. H.& Mitchison, T. J.: Control of actin polymerization in live and permeabilized fibroblasts. J. Cell Biol. 114, 503-513 (1991).

24. Okabe, S.& Hirokawa, N.: Actin dynamics in growth cones. J. Neurosci. 11, 1918-1929 (1991).

25. Theriot, J. A.& Mitchison, T. J.: Comparison of actin and cell surface dynamics in motile fibroblasts. J. Cell Biol. 118, 367-377 (1992).

26. Lin, C.-H.& Forscher, P.: Growth cone advance is inversely proportional to retrograde F-actin flow. Neuron 14, 763-771 (1995).

27. Fisher, G. W. Conrad, P. A. DeBiasio, R. L.& Taylor, D. L.: Centripetal transport of cytoplasm, actin and the cell surface in lamellipodia of fibroblasts. Cell Motil. Cytoskeleton 11, 235-247 (1988).

28. Forscher, P.& Smith, S. J.: Actions of cytochalasins on the organization of actin filaments and microtubules in a neuronal growth cone. J. Cell Biol. 107, 1505-1516 (1988).

29. Lin, C.-H. Espreafico, E. M. Mooseker, M. S.& Forscher, P.: Myosin drives retrograde F-actin flow in neuronal growth cones. Neuron 16, 769-782 (1996).

30. Higuchi, H.& Takemori, S.: Butanedione monoxime suppresses contraction and ATPase activity of rabbit skeletal muscle. J. Biochem. 105, 638-643 (1989).

31. Cramer, L. P.& Mitchison, T. J.: Myosin is involved in postmitotic cell spreading. J Cell Biol 131, 179-189 (1995).

32. Mogilner, A.& Oster, G.: The physics of lamellipodial protrusion. Eur. J. Biophys .25, 47-53 (1996).

33. Royal, D. Royal, M. Italiano, J. Roberts, T.& Soll, D., R.: In Ascaris sperm pseudopods, MSP fibers move proximally at a constant rate regardless of the forward rate of cellular translocation. Cell motil. cytoskeleton .31, 241-253 (1995).

34. Verkhovsky, A. B.& Borisy, G. G.: Non-sarcomeric mode of myosin II organization in the fibroblast lamellum. J. Cell Biol. 123, 637-652 (1993).

35. Verkhovsky, A. B. Svitkina, T. M.& Borisy, G. G.: Myosin II filament assemblies in the active lamella of fibroblasts: their morphogenesis and role in the formation of actin filament bundles. J. Cell Biol. 131, 989-1002 (1995).

36. Kucik, D. F. Elson, E. L.& Sheetz, M. P.: Cell migration does not produce membrane flow. J. Cell Biol. 111, 1617-1622 (1990).

37. Theriot, J. A.& Mitchison, T. J.: Actin microfilament dynamics in locomoting cells. Nature 352, 126-131 (1991).

38. Harris, A.& Dunn, G.: Centripetal transport of attached particles on both surfaces of moving fibroblasts. Exp Cell Res. 73, 519-523 (1972).

39. P Y Jay: The biophysical mechanism of cell motility in Dictystelium discoideum. In: Ph. D. thesis. Washington University, St. Louis (1995)

40. Wang, F.-S. Wolenski, J. S. Cheney, R. E. Mooseker, M. S.& Jay, D. G.: Function of myosin-V in filopodial extension of neuronal growth cones. Science 273, 660-663 (1996).

41. Cramer, L. P.& Mitchison, T. J.: Investigation of the Mechanism of Retraction of the Cell Margin and Rearward Flow of Nodules during Mitotic Cell Rounding. Mol. Biol. Cell 8, 109-119 (1997).

42. Kucik, D. F. Elson, E. L.& Sheetz, M. P.: Forward transport of glycoproteins on leading lamellipodia in locomoting cells. Nature 340, 315-317 (1989).

43. Sheetz, M. P. Baumrind, N. L. Wayne, D. B.& Pearlman, A. L.: Concentration of membrane antigens by forwards transport and trapping in neuronal growth cones. Cell 61, 231-241 (1990).

44. Schmidt, C., E. Chen, T.& Lauffenburger, D., A.: Simulation of integrin-cytoskeletal interactions in migrating fibroblasts. Biophys. J .67, 461-474 (1994).

45. D'Andrea, L. Danon, M. A. Sgourdas, G. P.& Bonder, E. M.: Identification of coelomocyte unconventional myosin and its association with in vivo particle/vesicle motility. J. Cell Sci. 107, 2081-2094 (1994).

46. Evans, L. L. Hammer, J.& Bridgman, P. C.: Subcellular localization of myosin V in nerve growth cones and outgrowth from dilute-lethal neurons. J. Cell Sci. 110, 439-449 (1997).

47. Goodson, H. V. Valetti, C.& Kreis, T. E.: Motors and membrane traffic. Curr. Opin. Cell Biol 9, 18-28 (1997).

48. Temm-Grove, C. Helbing, D. Wiegand, C. Honer, B.& Jockusch, B. M.: The upright position of brush border-type microvilli depends on myosin filaments. J. Cell Sci. 101, 599-610 (1992).

49. Dai& Sheetz, M.: Axon membrane flows from the growth cone to the cell body. Cell 83, 693-701 (1995).

50. Bretscher, M. S.: Directed lipid flow in cell membranes. Nature 260, 21-23 (1976).

51. Bretscher, M. S.: Moving membrane up to the front of migrating cells. Cell 85, 465-467 (1996).

52. Lee, L. Gustafsson, M. Magnusson, K.-E.& Jacobson, K.: The direction of membrane lipid flow in locomoting polymorphonuclear leukocytes. Science 247, 1229-1233 (1990).

53. Bray, D.: Model for membrane movements in the neural growth cone. Nature 244, 93-96 (1973).

54. Dai, J.& Sheetz, M. P.: Mechanical properties of neuronal growth cone membranes studied by tether formation with laser optical tweezers. Biophys. J .68, 988-996 (1995).

55. Mitchison, T.& Kirschner, M.: Cytoskeletal dynamics and nerve growth. Neuron 1, 761-772 (1988).

56. Heath, J. P.& Holifield, B. F.: On the mechanisms of cortical actin flow and its role in cytoskeletal organisation of fibroblasts. Symp. Soc. Exp. Biol. 47, 35-56 (1993).