[Frontiers in Bioscience 2, d471-481, September 15, 1997]

Table of Conents
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Guillermo G. Gomez

Department of Animal Science, North Carolina State University, Raleigh, NC 27695-7626 and Center for Gastrointestinal Biology and Diseases, Chapel Hill and Raleigh, NC

Received 9/5/97 Accepted 9/10/97


1. H.B. Greenberg, R.G. Wyatt, A.R. Kalica, R.H. Yolken, R. Black, A.Z. Kapikian & R.M. Chanock: New insights in viral gastroenteritis. Perspect Virol 11, 163-187 (1981)

2. J.L. Wolf & D.S. Schreiber: Viral gastroenteritis. Med Clin N Am 66, 575-595 (1982)

3. C.W. LeBaron, J. Lew, R.I. Glass, J.M. Weber & G.M. Ruiz-Palacios: Annual rotavirus epidemic patterns in North America. Results of a 5-year retrospective survey of 88 centers in Canada, Mexico, and the United States. J Am Med Assoc 264, 983-988 (1990)

4. E. Jawetz, J.L. Melnick & E.A. Adelberg: Reoviruses, rotaviruses & other human viral infections, in Rev Med Microbiol, Appleton and Lange, Norwalk, CT, pp 513-516 (1987)

5. T.H. Flewett & G.N. Woode: The rotaviruses, brief review. Arch Virol 57, 1-23 (1978)

6. M.S. McNulty: Rotaviruses. J gen Virol 40, 1-18 (1978)

7. J.C. Bridger, G.N. Woode, J.M. Jones, T.H. Flewett, A.S. Bryden & H. Davies: Transmission of human rotaviruses to gnotobiotic piglets. J Med Microbiol 8, 565-569 (1975)

8. P.J. Middleton, M. Petric & M.T. Szymanski: Propagation of infantile gastroenteritis virus (Orbi-group) in conventional and germfree piglets. Infect Immun 12, 1276-1280 (1975)

9. G.A. Hall, J.C. Bridger, R.L. Chandler & G.N. Woode: Gnotobiotic piglets experimentally infected with neonatal calf diarrhoea reovirus-like agent (Rotavirus). Vet Pathol 13, 197-210 (1976)

10. A. Torres-Medina, R.G. Wyatt, C.A. Mebus, N.R. Underdahl & A.Z. Kapikian: Diarrhea caused in gnotobiotic piglets by the reovirus-like agent of human infantile gastroenteritis. J Infect Dis 133, 22-27 (1976)

11. A. Torres-Medina, R.G. Wyatt, C.A. Mebus, N.R. Underdahl & A.Z. Kapikian: Patterns of shedding of human reovirus-like agent in gnotobiotic newborn piglets with experimentally-induced diarrhea. Intervirology 7, 250-255 (1976)

12. C.F. Crouch & G.N. Woode: Serial studies of virus multiplication and intestinal damage in gnotobiotic piglets infected with rotavirus. J Med Microbiol 11, 325-334 (1978)

13. K.W. Theil, E.H. Bohl, R.F. Cross, E.M. Kohler & A.G. Agnes: Pathogenesis of porcine rotaviral infection in experimentally inoculated gnotobiotic pigs. Am J Vet Res 39, 213-220 (1978)

14. S.R. Tzipori & I.H. Williams: Diarrhoea in piglets inoculated with rotavirus. Aust Vet J 54, 188-192 (1978)

15. S.R. Tzipori, T.J. Makin & M.L. Smith: The clinical response of gnotobiotic calves, pigs and lambs to inoculation with human, calf, pig and foal rotavirus isolates. Aust J Exp Biol Med Sci 58, 309-318 (1980)

16. R.T. Zijlstra, J. Odle, W.F. Hall, B.W. Petschow, H.B. Gelberg & R.E. Litov: Effect of orally administered epidermal growth factor on intestinal recovery of neonatal pigs infected with rotavirus. J. Ped Gastroenterology & Nutr 19, 382-390 (1994)

17. G.P. Davidson, D.G. Gall, M. Petric, D.G. Butler & J.R. Hamilton: Human rotavirus enteritis induced in conventional piglets. J Clin Invest 60, 1402-1409 (1977)

18. J.G. Lecce, M.W. King & W.E. Dorsey: Rearing regimen producing piglet diarrhea (Rotavirus) and its relevance to acute infantile diarrhea. Science 199, 776-778 (1978)

19. J.G. Lecce, J.M. Cummins & A.B. Richards: Treatment of rotavirus infection in neonate and weanling pigs using natural human interferon alpha. Mol Biother 2, 211-216 (1990)

20. J.M. Rhoads, E.O. Keku, J. Quinn, J. Woseley & J.G. Lecce: L-Glutamine stimulates jejunal sodium and chloride absorption in pig rotavirus enteritis. Gastroenterology 100, 683-691 (1991)

21. J.M. Rhoads, G.G. Gomez, W. Chen, R. Goforth, R.A. Argenzio & M.J. Neylan: Can a super oral rehydration solution stimulate intestinal repair in acute viral enteritis? J Diarrhoeal Dis Res 14, 175-181 (1996)

22. G.G. Gomez, E.J. Rozhon, R.A. Goforth & O. Thirakoune: An experimental rotaviral enteritis model with neonatal pigs. In: Advances in swine in biomedical research. Eds: Tumbleson, M.E. & Schook, L.B., Plenum Press, NY Vol 2, 811-819 (1996)

23. M.E. Conner, M.K. Estes & D.Y. Graham: Rabbit model of rotavirus infection. J Virol 62, 1625-1633 (1988)

24. B.A.M. Hambraeus, L.E.J. Hambraeus & G. Wadell: Animal model of rotavirus infection in rabbits - protection obtained without shedding of viral antigen. Arch Virol 107, 237-251 (1989)

25. K.I.R. Coelho, A.S. Bryden, C. Hall & T.H. Flewett: Pathology of rotavirus infection in suckling mice: A study by conventional histology, immunofluorescence, ultrathin sections, and scanning electron microscopy. Ultrastruct Pathol 2, 59-80 (1981)

26. M.K. Ijaz, D. Dent, D. Haines & L.A. Babiuk: Development of a murine model to study the pathogenesis of rotavirus infection. Exp Mol Pathol 51, 186-204 (1989)

27. R.C. Meyer, E.H. Bohl & E.M. Kohler: Procurement and maintenance of germ-free swine for microbiological investigations. Applied Microbiol 12, 295-300 (1964)

28. D.L. Schneider & H.P. Sarett: Use of hysterectomy-obtained SPF pigs for nutritional studies of the neonate. J Nutr 89, 43-48 (1966)

29. J.G. Lecce, M.W. King & R. Mock: Reovirus-like agent associated with fatal diarrhea in neonatal pigs. Infect Immun 14, 816-825 (1976).

30. A.Z. Kapikian, H.W. Kim, R.G. Wyatt, W.L. Cline, J.O. Arrobio, C.D. Brandt, W.J. Rodriguez, D.A. Sack, R.M. Chanock & R.H. Parrott: Human reovirus-like agent as the major pathogen associated with "winter" gastroenteritis in hospitalized infants and young children. New Engl J Med 294, 965-972 (1976)

31. J.E. Banatvala, I.L. Chrystie & B.M. Totterdell: Rotaviral infections in human neonates. JAVMA 173, 527-530 (1978)

32. S.M. Cook, R.I. Glass, C.W. LeBaron & M-S. Ho: Global seasonality of rotavirus infections. Bull WHO 68, 171-177 (1990)

33. J.B. Kurtz, T.W. Lee & A.J. Parsons: The action of alcohols on rotavirus, astrovirus and enterovirus. J Hosp Infect 1, 321-325 (1980)

34. J.A. Tan & R.D. Schnagl: Inactivation of a rotavirus by disinfectants. Med J Aust 1, 19-23 (1981)

35. J.G. Lecce: Absorption of macromolecules by neonatal intestine. Biol Neonat 9, 50-61 (1965/66)

36. J.G. Lecce & D.O. Morgan: Effect of dietary regimen on cessation of intestinal absorption of large molecules (closure) in the neonatal pig and lamb. J Nutr 78, 263-268 (1962)

37. J.G. Lecce, D.O. Morgan & G. Matrone: Effect of feeding colostral and milk components on the cessation of intestinal absorption of large molecules (closure) in neonatal pigs. J Nutr 84, 43-48 (1964)

38. J.G. Lecce & G. Matrone: Porcine neonatal nutrition: the effect of diet on blood serum proteins and performance of the baby pig. J Nutr 70, 13-20 (1960)

39. J.G. Lecce, G. Matrone & D.O. Morgan: The effect of diet on the maturation of the neonatal piglet's serum protein profile and resistance to disease. Ann N Y Acad Sci 94, 250-264 (1961)

40. P. Porter: Transfer of immunoglobulins IgG, IgA and IgM to lacteal secretions in the parturient sow and their absorption by the neonatal piglet. Biochim Biophys Acta 181, 381-392 (l969)

41. J.A. Coalson & J.G. Lecce: Influence of nursing intervals on changes in serum proteins (immunoglobulins) in neonatal pigs. J Anim Sci 36, 381-385 (1973)

42. F. Klobasa, E. Werhahn & J.E. Butler: Regulation of humoral immunity in the piglet by immunoglobulins of maternal origin. Res Vet Sci 31, 195-206 (1981)

43. E. Werhahn, F. Klobasa & J.E. Butler: Investigation of some factors which influence the absorption of IgG by the neonatal piglet. Vet Immunol Immunopathol 2, 35-51 (1981)

44. L.K. Bustad, W.E. Ham & T.J. Cunha: Preliminary observations on using a synthetic milk for raising pigs from birth. Arch Biochem 17, 249-260 (1948)

45. D.V. Catron, L.F. Nelson, G.C. Ashton & H.M. Maddock: Development of practical synthetic milk formulas for baby pigs. J Anim Sci 12, 62-76 (1953)

46. J.A. Coalson & J.G. Lecce: Herd differences in the expression of fatal diarrhea in artificially reared piglets weaned after 12 hours vs. 36 hours of nursing. J Anim Sci 36, 1114-1121 (1973)

47. G.G. Gomez, R.S. Sandler & E. Seal, Jr.: High levels of inorganic sulfate cause diarrhea in neonatal piglets. J Nutr 125, 2325-2332 (1995)

48. B.D. Owen, J.M. Bell, C.M. Williams & R.G. Oakes: Effects of porcine immune globulin administration on the survival and serum protein composition of colostrum-deprived piglets reared in a non-isolated environment. Can J Anim Sci 41, 236-252 (1961)

49. B.D. Owen & J.M. Bell: Further studies of survival and serum protein composition in colostrum-deprived pigs reared in a non-isolated environment. Can J Anim Sci 44, 1-7 (1964)

50. A. Scoot, B.D. Owen & J.L. Agar: Influence of orally administered porcine immunoglobulins on survival and performance of newborn colostrum-deprived pigs. J Anim Sci 35, 1201-1205 (1972)

51. I.M. McCallum, J.I. Elliot & B.D. Owen: Survival of colostrum-deprived neonatal piglets fed gamma-globulins. Can J Anim Sci 57, 151-158 (1977)

52. M.D. Drew & B.D. Owen: The provision of passive immunity to colostrum-deprived piglets by bovine or porcine serum immunoglobulins. Can J Anim Sci 68, 1277-1284 (1988)

53. J.G. Lecce: Rearing colostrum-free pigs in an automatic feeding device. J Anim Sci 28, 27-33 (1969).

54. J.G. Lecce & M.W. King: Rotaviral antibodies in cow's milk. Can J comp Med 46, 434-436 (1982)

55. J.C. Bridger & J.F. Brown: Development of immunity to porcine rotavirus in piglets protected from disease by bovine colostrum. Infect Immun 31, 906-910 (1981)

56. H. Brüssow, H. Hilpert, I. Walther. J. Sidoti, C. Mietens & P. Bachmann: Bovine milk immunoglobulins for passive immunity to infantile rotavirus gastroenteritis. J Clin Microb 25, 982-986 (1987)

57. H. Hilpert, H. Brüssow, C. Mietens, J. Sidoti, L. Lerner & H. Werchau: Use of bovine milk concentrate containing antibody to rotavirus to treat rotavirus gastroenteritis in infants. J Infect Dis 156, 158-166 (1987)

58. S.M. Innis & R. Dyer: Dietary triacylglycerols with palmitic acid (16:0) in the 2-position increase 16:0 in the 2-position of plasma and chylomicron triacylglycerols, but reduce phospholipid arachidonic and docosahexaenoic acids, and alter cholesteryl ester metabolism in formula-fed piglets. J Nutr 127, 1311-1319 (1997)

59. J.G. Lecce & J.A. Coalson: Diets for rearing colostrum-free piglets with an automatic feeding device. J Anim Sci 42, 622-629 (1976)

60. M.A. Varley, V.R. Fowler & A. Maitland: A rearing system for colostrum-deprived neonatal piglets. Lab Animals 19, 290-296 (1985)

61. R.E. McClead Jr., M.E. Lentz & R. Vieth: A simple technique to feed newborn piglets. J Ped Gastroenterology & Nutr 10, 107-110 (1990)

62. G.G. Gomez, O. Phillips & R.A. Goforth: Effect of immunoglobulin source on survival, growth, and hematological and immunological variables in pigs. J Anim Sci (in press).

63. R. Braude, K.G. Mitchell, M.J. Newport & J.W.G. Porter: Artificial rearing of pigs. 1. Effect of frequency and level of feeding on performance and digestion of milk proteins. Br J Nutr 24, 501-516 (1970)

64. D.Y. Graham, G.R. Dufour & M.K. Estes: Minimal infective dose of rotavirus. Arch Virol 92, 261-267 (1987)

65. M.K. Estes: Rotaviruses and their replication. In Virology, 2nd ed. Eds: B.N. Fields, D.M. Knipe, R.M. Chanock, M.S. Hirsch, J.L. Melnick, T.P. Monath & B. Roizman, Raven Press, Ltd., NY Vol 2, 1329-1352 (1990)

66. D.Y. Graham, J.W. Sackman & M.K. Estes: Pathogenesis of rotavirus-induced diarrhea. Preliminary studies in miniature swine piglet. Dig Dis Sci 29, 1028-1035 (1984).

67. M.J. Manners & J.A. Stevens: Changes from birth to maturity in the pattern of distribution of lactase and sucrase activity in the mucosa of small intestine of pigs. Br J Nutr 28, 113-127 (1972)

68. I.H. Holmes, R.D. Schngal, S.M. Rodger, B.J. Ruck, I.D. Gust, R.F. Bishop & G.L. Barnes: Is lactase the receptor and uncoating enzyme for infantile enteritis (rota)viruses?. Lancet i,1387-1389 (1976)

69. G.P. Davidson & G.L. Barnes: Structural and functional abnormalities of the small intestine in infants and young children with rotavirus enteritis. Acta Pediatr Scand 68, 181-186 (1979)