[Frontiers in Bioscience2, e28-33, May 15, 1997]
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CAVEAT LECTOR



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VASCULAR REACTIVITY FOLLOWING ISCHEMIA/REPERFUSION

Joseph N. Benoit1 & Mark S. Taylor

Department of Physiology, University of South Alabama, College of Medicine, Mobile, Alabama 36688

Received 4/19/97; Accepted 4/30/97; On-line 5/15/97

TABLE OF CONTENTS

1. Abstract
2. Introduction
3. Mechanism of vascular contraction and relaxation
3.1 Cellular mechanism of receptor mediated vasoconstriction in normal blood vessels
3.2 Mechanism of vasodilation in normal blood vessels
3.3 Cellular mechanism of cAMP dependent vasodilation
3.4 Mechanism of cGMP dependent vasodilation
4. Reactive oxygen metabolites in ischemia/reperfusion
5. Alterations in vasoconstrictor function associated with ischemia/reperfusion
6. Acknowledgment
7. References
8. Entire manuscript

Key Words: vascular smooth muscle, vasoconstriction, vasodilation, free radicals, reactive oxygen species, hypoxia/reoxygenation