[Frontiers in Bioscience 3, a23-26, May 1, 1998]
Reprints
PubMed
CAVEAT LECTOR




Table of Conents
 Previous Section   Next Section

AMINOALKYLAZIRIDINES AS SUBSTRATES AND INHIBITORS OF LYSYL OXIDASE: SPECIFIC INACTIVATION OF THE ENZYME BY N-(5-AMINOPENTYL)AZIRIDINE

Narasimhan Nagan1, Patrick S. Callery2 and Herbert M. Kagan1

1 Department of Biochemistry, Boston University School of Medicine, 80 East Concord Street, Boston, MA 02118, and the 2 Department of Pharmaceutical Sciences, School of Pharmacy, West Virginia University, Morgantown, WV 26506

Received 4/2/98 Accepted4/6/98

TABLE OF CONTENTS

1. Abstract
2. Introduction
3. Materials and Methods
3.1. Enzyme purification and assay
4. Results
4.1 Substrate potential of aminoalkylaziridines
4.2 Competitive nature of inhibition
4.3 Irreversibility of inhibition
5. Discussion
6. Acknowledgement
7. References
8. Entire manuscript

Key words: Enzymology, Connective Tissue, Lysyl Oxidase, Aminoalkylaziridines, Enzyme Inhibition

Search OMIM (Online Mendelian Inheritance in Man) to find related articles
This form requires a WWW Client such as Netscape, XMosaic, Lynx that supports fill-in forms.

Enter one or more search keywords:

To Search all fields, leave the following boxes unchecked. To narrow your search to certain specific fields, check the boxes next to those fields' names. SeeQuery Help for other ways to search. Title: OMIM Number: Allelic Variants: Text: References: Clinical Synopsis: Gene Map Disorder: Contributors: See only records which have been changed in the past Display at most