[Frontiers in Bioscience 3, c8-16, March 25, 98]

	[Frontiers in Bioscience 3, c8-16, March 25, 98] Reprints PubMed CAVEAT LECTOR
	USE OF GENETICALLY ENGINEERED MICE AS MODELS FOR EXPLORING THE ROLE OF OXIDATIVE STRESS IN NEURODEGENERATIVE DISEASES Julie K. Andersen Division of Biogerontology, Andrus Gerontology Center, University of Southern California, Los Angeles, CA 90089-0191 Received 3/16/98 Accepted 3/20/98 4. CONCLUSION Irrespective of the primary causative events, it is likely that ROS generation plays a major role in the progression of neurodegenerative diseases and may, in fact, represent a common converging pathway in the development of neuronal cell death. Genetically engineered animals have been and will continue to be an extremely important component in the on-going analysis in this field of research.

[Frontiers in Bioscience 3, c8-16, March 25, 98]
Reprints
PubMed
CAVEAT LECTOR

USE OF GENETICALLY ENGINEERED MICE AS MODELS FOR EXPLORING THE ROLE OF OXIDATIVE STRESS IN NEURODEGENERATIVE DISEASES

Julie K. Andersen

Division of Biogerontology, Andrus Gerontology Center, University of Southern California, Los Angeles, CA 90089-0191

Received 3/16/98 Accepted 3/20/98

4. CONCLUSION

Irrespective of the primary causative events, it is likely that ROS generation plays a major role in the progression of neurodegenerative diseases and may, in fact, represent a common converging pathway in the development of neuronal cell death. Genetically engineered animals have been and will continue to be an extremely important component in the on-going analysis in this field of research.