[Frontiers in Bioscience 3, c27-33, May 1, 1998]

	[Frontiers in Bioscience 3, c27-33, May 1, 1998] Reprints PubMed CAVEAT LECTOR
	LURIE’S TUBERCLE-COUNT METHOD TO TEST TB VACCINE EFFICACY IN RABBITS Arthur M. Dannenberg, Jr. Departments of Environmental Health Sciences, Molecular Microbiology and Immunology, and Epidemiology, School of Hygiene and Public Health; and the Department of Pathology, School of Medicine, The Johns Hopkins University, Baltimore, Maryland 21205 Received 3/9/98 Accepted 3/14/98 TABLE OF CONTENTS 1. Abstract 2. Introduction 3. Description of the tubercle-count method 4. Resistance to the establishment of the infection 5. Immune mechanisms controlling the progress of the early microscopic pulmonary lesion 6. How vaccines prevent grossly visible TB lesions 7. Effects of vaccines on the 5 stages of tuberculosis 7.1 Stage 1. Destruction of the bacillus by alveolar macrophages 7.2 Stage 2. Symbiosis 7.3 Stage 3. Initial caseous necrosis 7.4 Stage 4. Progression or regression of the established primary tubercle 7.5 Stage 5. Liquefaction and cavity formation 7.6. Relevance 8. Dose effects 9. Single primary TB lesions 10. Tuberculosis in different species 11. Application of the tubercle-count method to guinea pigs and mice 12. Summary 13. Acknowledgments 14. References 15. Entire manuscript Key words:Tuberculosis, T.B., Vaccine, Tubercle, Rabbit, Guinea pig, Mouse Search OMIM (Online Mendelian Inheritance in Man) to find related articles This form requires a WWW Client such as Netscape, XMosaic, Lynx that supports fill-in forms. Enter one or more search keywords: To Search all fields, leave the following boxes unchecked. To narrow your search to certain specific fields, check the boxes next to those fields' names. SeeQuery Help for other ways to search. Title: OMIM Number: Allelic Variants: Text: References: Clinical Synopsis: Gene Map Disorder: Contributors: See only records which have been changed in the past Display at most

[Frontiers in Bioscience 3, c27-33, May 1, 1998]
Reprints
PubMed
CAVEAT LECTOR

LURIE’S TUBERCLE-COUNT METHOD TO TEST TB VACCINE EFFICACY IN RABBITS

Arthur M. Dannenberg, Jr.

Departments of Environmental Health Sciences, Molecular Microbiology and Immunology, and Epidemiology, School of Hygiene and Public Health; and the Department of Pathology, School of Medicine, The Johns Hopkins University, Baltimore, Maryland 21205

Received 3/9/98 Accepted 3/14/98

TABLE OF CONTENTS

1. Abstract
2. Introduction
3. Description of the tubercle-count method
4. Resistance to the establishment of the infection
5. Immune mechanisms controlling the progress of the early microscopic pulmonary lesion
6. How vaccines prevent grossly visible TB lesions
7. Effects of vaccines on the 5 stages of tuberculosis: 7.1 Stage 1. Destruction of the bacillus by alveolar macrophages
7.2 Stage 2. Symbiosis
7.3 Stage 3. Initial caseous necrosis
7.4 Stage 4. Progression or regression of the established primary tubercle
7.5 Stage 5. Liquefaction and cavity formation
7.6. Relevance
8. Dose effects
9. Single primary TB lesions
10. Tuberculosis in different species
11. Application of the tubercle-count method to guinea pigs and mice
12. Summary
13. Acknowledgments
14. References
15. Entire manuscript

Key words:Tuberculosis, T.B., Vaccine, Tubercle, Rabbit, Guinea pig, Mouse

Search OMIM (Online Mendelian Inheritance in Man) to find related articles
This form requires a WWW Client such as Netscape, XMosaic, Lynx that supports fill-in forms.