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[Frontiers in Bioscience 3, d922-933, August 6, 1998] Reprints PubMed CAVEAT LECTOR |
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AROMATASE AND BREAST CANCER Division of Immunology, Beckman Research Institute of the City of Hope, Duarte, CA 91010
Received 12/18/97 Accepted 7/15/98 9. REFERENCES 1. Green, S.: Steroid receptors and new (anti-) steroidal agents: modulation of oestrogen receptor activity by oestrogens and anti-oestrogens. J. Steroid Biochem. Mol. Biol. 37, 747-751 (1990) 2. Lippman, M. E., Dickson, R. B., Kasid, A., Gelmann, E., Davidson, N., McManaway, M., Huff, K., Bronzert, D., Bates, S., Swain, S., et al.: Autocrine and paracrine growth regulation of human breast cancer. J. Steroid Biochem. 24, 147-154 (1986) 3. Bates, S. E., Davidson, N. E., Valverius, E. M., Freter, C. E., Dickson, R. B., Tam, J. P., Kudlow, J. E., Lippman, M. E., and Salomon, D. S.: Expression of transforming growth factor alpha and its messenger ribonucleic acid in human breast cancer: its regulation by estrogen and its possible functional significance. Mol. Endocrinol. 2, 543-555 (1988) 4. James, V.H.T., McNeill, J.M., Lai, L.C., Newton, C.J., Ghilchik, M.W., and Reed, M.J.: Aromatase activity in normal breast and breast tumor tissues: in vivo and in vitro studies. Steroids 50, 269-279 (1987) 5. Miller, W. R., and O'Neill, J.: The importance of local synthesis of estrogen within the breast. Steroids 50, 537-548 (1987) 6. Bulum, S. E., Price, T. M., Mahendroo, M. S., Aitken, J., and Simpson, E. R. : A link between breast cancer and local estrogen biosynthesis suggested by quantification of breast adipose tissue aromatase cytochrome P450 transcripts using competitive polymerase chain reaction after reverse transcription. J. Clin. Endocrinol. Metab. 77, 1622-1628 (1993) 7. Harada, N.: Aberrant expression of aromatase in breast cancer tissues. J. Steroid Biochem. Mol. Biol. 61, 175-184 (1997) 8. Pasqualini, J. R., Chetrite, G., Blacker, C., Feinstein, M. C., Delalonde, L., Talbi, M., and Maloche, C.: Concentrations of estrone, estradiol, and estrone sulfate and evaluation of sulfatase and aromatase activities in pre- and postmenopausal breast cancer patients. J. Clin. Endocrinology and Metablism 81, 1460-1464 (1996) 9. Zhou, C., Zhou, D., Esteban, J., Murai, J., Siiteri, P.K., Wilczynski, S., and Chen, S.: Aromatase gene expression and its exon I usage in human breast tumors. Detection of aromatase messenger RNA by reverse transcription-polymerase chain reaction (RT-PCR) J. Steroid Biochem. Mol. Biol. 59, 163-171 (1996) 10. Esteban, J.M., Warsi, Z., Haniu, M., Hall, P.F., Shively, J.E., and Chen, S.: Detection of intratumoral aromatase in breast carcinomas, an immunohistochemical study with clinico-pathologic correlation. J. Amer. Pathol. 140, 337-343 (1992) 11. Sasano, H., Nagura, H., Harada, N., Goukon, Y., and Kimura, M.: Immunolocalization of aromatase and other steroidogenic enzymes in human breast disorders. Hum. Pathol. 25, 530-535 (1994) 12. Santen, R. J., Martel, J., Hoagland, M., Naftolin, F., Roa, L., Harada, N., Hafer, L., Zaino, R., and Santner, S. J.: Stromal spindle cells contain aromatase in human breast tumors. J. Clin. Endocrinol. Metab. 79, 627-632 (1994) 13. Lu, Q., Nakamura, J., Savinov, A., Yue, W., Weisz, J., Dabbs, D.J., Wolz, G., and Brodie, A.: Expression of aromatase protein and messenger ribonucleic acid in tumor epithelial cells and evidence of functional significance of locally produced estrogen in human breast cancers. Endocrinology 137, 3061-3077 (1996) 14. Kitawaki, J., Fukuoka, M., Yamamoto, T., Honjo, H., and Okada, H.: Contribution of aromatase to the deoxyribonucleic acid synthesis of MCF-7 human breast cancer cells and its suppression by aromatase inhibitors. J. Steroid Biochem. Molec. Biol. 42, 267-277 (1992) 15. Zhou, D., Pompon, D., and Chen, S.: Stable expression of human aromatase cDNA in mammalian cells - A useful system for aromatase inhibitor screening. Cancer Res. 50, 6949-6954 (1990) 16. Santner, S.J., Chen, S., Zhou, D., Korsunsky, Z., Martel, J., and Santen, R.J.: Effect of androstenedione on growth of untransfected and aromatase-transfected MCF-7 cells in culture. J. Steroid Biochem. Mol. Biol. 44, 611-616 (1993)
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