[Frontiers in Bioscience 3, d502-508, May 15, 1998]
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THE KERATINOCYTE GROWTH-DIFFERENTIATION SWITCH

Paolo Dotto

Cutaneous Biology Research Center, Massachusetts General Hospital, Building 149, 13th Street, Charlestown, Massachusetts, 02129-2000

Received 5/4/98 Accepted 5/8/98

TABLE OF CONTENTS

1. Abstract
2. Introduction
3. Signals which control the switch between keratinocyte growth and differentiation
4. Intermediate signalling pathways which are responsible for transduction of the differentiation signal
5. Tyrosine phosphorylation : key to regulation of keratinocyte differentiation
6. Transcription and cell cycle regulatory events connected with the onset of keratinocyte differentiation
7. References
8. Entire manuscript

Key words: Keratinocyte, Growth, Differentiation, Cell Biology, Epithelial Tissues, Signal Transduction, Cell Cycle, Transcription Factors

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