[Frontiers in Bioscience 3, d1039-1050, October 15, 1998]
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INTEGRINS DURING MUSCLE DEVELOPMENT AND IN MUSCULAR DYSTROPHIES

Donald Gullberg, Teet Velling, Lars Lohikangas, Carl-Fredrik Tiger

Department of Animal Physiology, Uppsala University, BMC, Box 596, S-751 24 Uppsala , Sweden

Received 9/7/98 Accepted 9/21/98

TABLE OF CONTENTS

1. Abstract
2. In vivo myogenesis
2.1. Early vertebrate myogenesis
2.2. Lessons from Drosophila myogenesis
3. In vitro myogenesis
4. Integrins during Muscle Development
4.1. Integrins as cell-cell receptors
4.2. Integrins as migration receptors
4.3. Integrins as signaling receptors
4.4. Integrins as mechanical links
5. Integrins in Muscular Dystrophy
5.1. Muscle regeneration
5.2. Fibrosis
5.3. Integrins as cell-cell receptors
5.4. Integrins as migration receptors
5.5. Integrins as signaling receptors
5.6. Integrins as mechanical links
6. Perspective
7. References
8. Entire manuscript

Key words: Somite, Drosophila, Muscle Development, Muscular dystrophy, Integrin, Extracellular Matrix

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