[Frontiers in Bioscience 3, d194-207, February 15, 1998]
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VASOPRESSIN SIGNALING PATHWAYS IN VASCULAR SMOOTH MUSCLE

Raphael A. Nemenoff

Department of Medicine, University of Colorado Health Sciences Center, Denver, CO 80262

Received 1/21/98 Accepted 2/4/98

TABLE OF CONTENTS

1. Abstract
2. Introduction
3. Physiologic effects of vasopressin in smooth muscle
4. Post-receptor signaling pathways
4.1. Mobilization of intracellular Ca2+
4.2. Regulation of protein kinase pathways
4.3. Regulation of arachidonic acid release and eicosanoid production
5. Effects on gene expression
5.1. Immediate early response genes 5.2. Smooth muscle-alpha-actin
6. Other effectors
7. Conclusion and further directions
8. Acknowledgments
9. References
10. Entire manuscript

Key words: Smooth muscle, Vasopressin, Vessel, Smooth muscle actin, Signal transduction, Protein kinases, c-Jun

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