[Frontiers in Bioscience, 3, d1109-1119, November 1, 1998]
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ROLE OF PHOSPHOLIPASES DURING SPERM ACROSOMAL EXOCYTOSIS

E.R.S. Roldan

Instituto de Bioquímica (CSIC-UCM), Facultad de Farmacia, Universidad Complutense, 28040-Madrid, Spain

Received 8/12/98 Accepted 9/30/98

TABLE OF CONTENTS

1. Abstract
2. Introduction
3. Phospholipase C
3.1. PPI-specific PLC (PIC)
3.2. PC-specific PLC
4. Phospholipase D
5. Phospholipase A2
5.1. Types of PLA2 in spermatozoa
5.2. Sperm PLA2 - Biochemical data
5.3. Activation of PLA2 during acrosomal exocytosis
5.4. Regulation of sperm PLA2
5.5. Roles of lysophospholipids and fatty acids
6. Perspective
7. References
8. Entire manuscript

Key words:Acrosome, Exocytosis, Phospholipases, Phospholipase C, Phospholipase D, Phospholipase A2, Spermatozoa.

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