[Frontiers in Bioscience 3, d913-921, August 6, 1998]

	[Frontiers in Bioscience 3, d913-921, August 6, 1998] Reprints PubMed CAVEAT LECTOR
	IS EXPOSURE TO ENVIRONMENTAL OR INDUSTRIAL ENDOCRINE DISRUPTING ESTROGEN-LIKE CHEMICALS ABLE TO CAUSE GENOMIC INSTABILITY? Deodutta Roy, John B. Colerangle and Kamleshwar Prasad Singh Department of Environmental Health Sciences, The University of Alabama at Birmingham, Birmingham, Alabama 35294-0008 Received 12/15/97Accepted 7/15/98 TABLE OF CONTENTS 1. Abstract 2. Introduction 3. Numerical changes in the genome 4. Structural changes in the genome 4.1. Covalent interaction with the genome 4.2. Telomeric loss 4.3. Telomeric associations 4.4. Chromatid/chromosomal breaks 5. Impaired expression of transcription-regulating and DNA repair proteins and protooncoproteins indicating genomic instability 6. Acknowledgment 7. References 8. Entire manuscript Key words: Endocrine disruptors, Estrogen, Genome, Instability Search OMIM (Online Mendelian Inheritance in Man) to find related articles This form requires a WWW Client such as Netscape, XMosaic, Lynx that supports fill-in forms. Enter one or more search keywords: To Search all fields, leave the following boxes unchecked. To narrow your search to certain specific fields, check the boxes next to those fields' names. SeeQuery Help for other ways to search. Title: OMIM Number: Allelic Variants: Text: References: Clinical Synopsis: Gene Map Disorder: Contributors: See only records which have been changed in the past Display at most

[Frontiers in Bioscience 3, d913-921, August 6, 1998]
Reprints
PubMed
CAVEAT LECTOR

IS EXPOSURE TO ENVIRONMENTAL OR INDUSTRIAL ENDOCRINE DISRUPTING ESTROGEN-LIKE CHEMICALS ABLE TO CAUSE GENOMIC INSTABILITY?

Deodutta Roy, John B. Colerangle and Kamleshwar Prasad Singh

Department of Environmental Health Sciences, The University of Alabama at Birmingham, Birmingham, Alabama 35294-0008

Received 12/15/97Accepted 7/15/98

TABLE OF CONTENTS

1. Abstract
2. Introduction
3. Numerical changes in the genome
4. Structural changes in the genome: 4.1. Covalent interaction with the genome
4.2. Telomeric loss
4.3. Telomeric associations
4.4. Chromatid/chromosomal breaks
5. Impaired expression of transcription-regulating and DNA repair proteins and protooncoproteins indicating genomic instability
6. Acknowledgment
7. References
8. Entire manuscript

Key words: Endocrine disruptors, Estrogen, Genome, Instability

Search OMIM (Online Mendelian Inheritance in Man) to find related articles
This form requires a WWW Client such as Netscape, XMosaic, Lynx that supports fill-in forms.