[Frontiers in Bioscience, 3, d348-353, March 17, 1998]
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TRANSCRIPTIONAL REGULATION OF ALPHA-1 ADRENERGIC RECEPTORS

Daniel R. Scanga1 and Debra A. Schwinn2,3,4

School of Medicine,1 Departments of Anesthesiology,2 Surgery,3 and Pharmacology/Cancer Biology, 4 Duke University Medical Center, Durham, NC 27710

Received 2/25/98 Accepted 3/2/98

TABLE OF CONTENTS

1. Abstract
2. Introduction
3. 5 untranslated region and putative regulatory consensus sequences
4. Identification of transcription initiation sites
5. Use of reporter constructs to define promoters
6. Transcription initiation in TATA-less promoters
7. Multiple promoters
8. Cell-specific expression of adrenergic receptor mRNAs
9. Modulation of gene expression via cis-acting elements
10. Perspectives
11. Acknowledgments
12. References
13. Entire manuscript

Key words: Receptor, Adrenergic, Alpha-adrenergic, Gene, 5' flanking region, cis regulatory element, Reporter construct, Transcriptional regulation

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