[Frontiers in Bioscience 3, d729-738, July 26, 1998]

	[Frontiers in Bioscience 3, d729-738, July 26, 1998] Reprints PubMed CAVEAT LECTOR
	ENDOCYTOSIS AND INTRACELLULAR SORTING OF RECEPTOR TYROSINE KINASES Alexander Sorkin Department of Pharmacology, University of Colorado Health Sciences Center, Denver, CO 80262, USA Received 5/29/98 Accepted 5/8/98 TABLE OF CONTENTS 1. Abstract 2. Introduction: Receptor-mediated endocytosis 3. Endocytosis of growth factor receptors: down-regulation 4. Internalization 4.1. Receptor recruitment into clathrin-coated pits 4.2. Molecular mechanisms of internalization 5. Intracellular sorting 5.1. Pathway through endosomes 5.2. Kinetics of intracellular trafficking: recycling versus degradation 5.3. Possible mechanisms of receptor sorting in endosomes 6. Role of endocytosis in growth factor signaling 7. Perspectives 8. Acknowledgments 9. References 10. Entire manuscript Key words: Cell Biology; Mammalian Cells; Endocytosis; Intracellular Trafficking; Growth Factor Receptors Search OMIM (Online Mendelian Inheritance in Man) to find related articles This form requires a WWW Client such as Netscape, XMosaic, Lynx that supports fill-in forms. Enter one or more search keywords: To Search all fields, leave the following boxes unchecked. To narrow your search to certain specific fields, check the boxes next to those fields' names. SeeQuery Help for other ways to search. Title: OMIM Number: Allelic Variants: Text: References: Clinical Synopsis: Gene Map Disorder: Contributors: See only records which have been changed in the past Display at most

[Frontiers in Bioscience 3, d729-738, July 26, 1998]
Reprints
PubMed
CAVEAT LECTOR

ENDOCYTOSIS AND INTRACELLULAR SORTING OF RECEPTOR TYROSINE KINASES

Alexander Sorkin

Department of Pharmacology, University of Colorado Health Sciences Center, Denver, CO 80262, USA

Received 5/29/98 Accepted 5/8/98

TABLE OF CONTENTS

1. Abstract
2. Introduction: Receptor-mediated endocytosis
3. Endocytosis of growth factor receptors: down-regulation
4. Internalization: 4.1. Receptor recruitment into clathrin-coated pits
4.2. Molecular mechanisms of internalization
5. Intracellular sorting: 5.1. Pathway through endosomes
5.2. Kinetics of intracellular trafficking: recycling versus degradation
5.3. Possible mechanisms of receptor sorting in endosomes
6. Role of endocytosis in growth factor signaling
7. Perspectives
8. Acknowledgments
9. References
10. Entire manuscript

Key words: Cell Biology; Mammalian Cells; Endocytosis; Intracellular Trafficking; Growth Factor Receptors

Search OMIM (Online Mendelian Inheritance in Man) to find related articles
This form requires a WWW Client such as Netscape, XMosaic, Lynx that supports fill-in forms.