[Frontiers in Bioscience, 3, d365-375, March 23, 98]
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SIGNAL TRANSDUCTION DURING APOPTOSIS; IMPLICATIONS FOR CANCER THERAPY

Michael Story1 and Reinhard Kodym2

1Department of Experimental Radiation Oncology, University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Blvd., Houston, TX 77030, 2 Klinic fur Strahlentherapie und Strahlenbiologie, Wahringer Gurtel 18-20, A-1090, Vienna, Austria

Received 2/15/98 Accepted 2/20/98

TABLE OF CONTENTS

1. Abstract
2. Introduction
3. Ceramide
4. Protein kinase C
5. NF-kappaB
6. p53
7. Bcl-2 and family members
8. Therapeutic applications
9. References
10. Entire manuscript

Key words: Apoptosis, Cancer therapy, p53, bcl-2, Ceramide

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