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SIGNALING THROUGH PROTEIN KINASE C
Alex Toker
Signal Transduction Group, Boston Biomedical Research Institute, 20 Staniford Street, Boston MA 02114, USA
Received 7/27/98 Accepted 11/22/98
TABLE OF CONTENTS
- 1. Abstract
- 2. Introduction
- 3. The PKC superfamily of enzymes
- 4. Regulation of PKC
- 4.1. Multiple lipid mediators
4.2. Phosphorylation
4.3. Structure
- 5. PKC Signaling
- 5.1. Substrate specificity
5.2. PKCepsilon
5.3. PKCzeta and PKClambda
5.4. PKCmu/PKD
- 6. Perspective
- 7. References
- 8. Entire manuscript
Key words: PKC, Signal Transduction, Protein kinase, Lipid kinase, Phosphorylation, Phospholipids, Phorbol Ester
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