TREATMENT OF ADVANCED AND METASTATIC PANCREATIC CANCER
Lawrence Blaszkowsky
Department of Medicine, The New England Medical Center, Boston, MA
Received 7/8/98 Accepted 8/5/98
TABLE OF CONTENTS 1. Abstract 2. Introduction 3. Single Agent Chemotherapy 3.1. Gemcitabine 3.2. 5- Fluoruracil 3.3. 5- Flurouracil Modulation 3.4. Other Cytotoxic Agents 4. Hormonal Therapy 5. Combination Chemotherapy Regimens 5.1. FAM Regimen 5.2. 5-FU + Nitrosoureas 5.3. FAM versus 5-FU + Nitrosourea Combinations 5.4. Mallinson Regimen 5.5. Platinum Regimens 5.6. 5-FU and Gemcitabine 5.7. Other 5-FU Combinations 6. Biological and Gene Therapy 7. Perspective 8. References 9. Entire manuscript Key words: Pancreatic cancer, Treatment, Chemotherapy
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