[Frontiers in Bioscience 3, e214-225, November 1, 1998]
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TREATMENT OF ADVANCED AND METASTATIC PANCREATIC CANCER

Lawrence Blaszkowsky

Department of Medicine, The New England Medical Center, Boston, MA

Received 7/8/98 Accepted 8/5/98

TABLE OF CONTENTS

1. Abstract
2. Introduction
3. Single Agent Chemotherapy
3.1. Gemcitabine
3.2. 5- Fluoruracil
3.3. 5- Flurouracil Modulation
3.4. Other Cytotoxic Agents
4. Hormonal Therapy
5. Combination Chemotherapy Regimens
5.1. FAM Regimen
5.2. 5-FU + Nitrosoureas
5.3. FAM versus 5-FU + Nitrosourea Combinations
5.4. Mallinson Regimen
5.5. Platinum Regimens
5.6. 5-FU and Gemcitabine
5.7. Other 5-FU Combinations
6. Biological and Gene Therapy
7. Perspective
8. References
9. Entire manuscript

Key words: Pancreatic cancer, Treatment, Chemotherapy

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