Akihide Kamiya ¹, Frank J. Gonzalez ², and Hiromitsu Nakauchi ¹

1 Laboratory of Stem Cell Therapy, The Institute of Medical Science, University of Tokyo, 4-6-1 Shirogane-dai, Minato-ku, Tokyo 108-8639, Japan, ² Laboratory of Metabolism, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892

FIGURES

Figure 1. Schematic representation of possible mechanisms of the hepatic stem cell system. Hepatocyte growth factor (HGF) induced early transition of albumin-negative stem cells into albumin-positive hepatic progenitor cells having bipotential differentiation (hepatocytes and cholangiocytes).