A review of autoimmune diseases associated with cancer
Patricia Tai1, Edward Yu2, Kurian Joseph3, Thomas Miale4
1
Faculty of Oncology, University of Saskatchewan, Saskatchewan; 2Department of Radiation Oncology, University of Western Ontario, London; 3Department of Radiation Oncology, University of Edmonton, Alberta; 4Department of Pediatric Oncology, Allan Blair Cancer Clinic, Saskatchewan, Canada
TABLE OF CONTENTS
- 1. Abstract
- 2. Introduction
- 3. Autoimmune diseases associated with increased cancer risk
- 3.1. Rheumatoid arthritis (RA)
- 3.2. Systemic lupus erythematosus (SLE)
- 3.3. Sjögren's syndrome (SS)
- 3.4. Celiac disease (Non-tropical sprue)
- 4. Autoimmune phenomenon with cancers - paraneoplastic syndromes
- 4.1. Neurological
- 4.1.1. Neuromuscular junction disorders
- 4.1.1.1. Lambert-Eaton myasthenic syndrome (LEMS)
- 4.1.1.2. Myasthenia Gravis (MG)
- 4.1.2. Dermatomyositis and polymyositis
- 4.2. Hematological
- 5. New perspectives on cancer vaccines
- 6. References
1. ABSTRACT
The focus of this review is on the relationships between autoimmune diseases and cancer from two closely related perspectives: 1.Those autoimmune diseases which are often associated with malignancies. 2.Those prevalent cancers which may increase the risks of developing autoimmune disorders. The review concludes with a brief discussion of some selected innovative approaches to cancer immunotherapy.
