[Frontiers in Bioscience E4, 101-110, January 1, 2012] |
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Bioconjugated nanomaterials on devices for infectious disease diagnostics Concepcion Ponce1, Philip Ian Padilla2, 3
1 TABLE OF CONTENTS
1. ABSTRACT The successful use of the nanoscale-dependent properties of nanomaterials on infectious diseases diagnostics devices lies on a well-engineered surface of both the probes and the transducer. Engineering probe and transducer surfaces involve functionalization of nanomaterials, conjugation to biorecognition elements and nanopatterning. This review presents the most common and most promising functional groups, bioconjugation schemes and patterning strategies of nanomaterials on sensing devices and their specific application to infectious pathogen detection. |