[Frontiers in Bioscience E4, 195-204, January 1, 2012]
Dietary patterns and prostatic diseases
Cimino Sebastiano1, Favilla Vincenzo1, Castelli Tommaso1, Sortino Giuseppe1, Russo Marco1, Caldarella Ivana1, Russo Giorgio1, Madonia Massimo2, Morgia Giuseppe1
1Department of Urology, University of Catania, Italy, 2Departement of Urology, University of Sassari, Italy
TABLE OF CONTENTS
Dietary patterns play a role on prostatic diseases in association with genetic, behavioral, occupational and environmental ones. Data from reviewed literature provide evidences of a possible relationship between dietary habits and the incidence of prostate disorders, even if it is not enough to justify a widespread adoption of new dietary habits. In this review the role of dietary patterns, including the use of supplements, in the prevention and treatment of the most frequent and known prostatic diseases, benign prostatic hyperplasia (BPH) and prostate cancer (PC) was analyzed. A limited number of well designed trials were identified in which diet and dietary supplement intervention appeared to slow disease progression. Although conclusive evidences are limited, the current data suggest that a diet low in total calories and fat, high in vegetables and fruits and that body weight control could be possibly effective in preventing prostatic diseases. On the other hand care must be taken to ensure that over-consumption of dietary supplements does not occur because it may be harmful.