[Frontiers in Bioscience S4, 167-180, January 1, 2012]

Potent natural aphrodisiacs for the management of erectile dysfunction and male sexual debilities

Singh Akhand Pratap1, Singh Rajender1

1Central Drug Research Institute, Council of Scientific and Industrial Research, Lucknow, U.P., India


1. Abstract
2. Introduction
3. Parameters of mating behavior test
4. Natural aphrodisiacs
4.1. Animal based aphrodisiac
4.1.1. Ambrein
4.1.2. Bufo toad
4.1.3. Spanish fly
4.2. Plant based aphrodisiac
4.2.1. Allium tuberosum
4.2.2. Alpinia calcarata
4.2.3. Astercantha longifolia
4.2.4. Anacyclus pyrethrum
4.2.5. Bulbus natalensis
4.2.6. Butea frondosa
4.2.7. Chlorophytum borivilianum
4.2.8. Caesalpinia benthamiana
4.2.9. Curculigo orchioides
4.2.10. Crocus sativus
4.2.11. Coryanthe yohimbe
4.2.12. Camellia sinensis
4.2.13. Dactylorhiza hatagirea
4.2.14. Eurycoma longifolia
4.2.15. Ferula hermonis
4.2.16. Fodogia agrestis
4.2.17. Ginseng
4.2.18. Lycium barbarum
4.2.19. Lepidium meyenii
4.2.20. Microdesmis keayana
4.2.21. Montanoa tomentosa
4.2.22. Mucuna pruriens
4.2.23. Mondia whitei
4.2.24. Passiflora incarnata
4.2.25. Securidaca longepedunculata
4.2.26. Syzygium aromaticum
4.2.27. Tribulus terrestris
4.2.28. Turnera diffusa
5. Discussion
6. Conclusion
7. Acknowledgements
8. References


The area of natural product research is rapidly progressing from traditional medicine to modern medicine having proper scientific basis of its usage. However, identifying the active constituent or the basis of its mechanism holds the key to synthesis of these drugs in the laboratory. Traditional Indian literature such as Ayurveda has listed several plant and animal based resources for treatment of almost every ailment. Erectile dysfunction and male sexual debilities are among the most explored areas in traditional medicine. A number of natural products, mostly plant based, have been claimed to cure erectile dysfunction and related male sexual debilities. These products often are aphrodisiac and have multi-fold effects on male reproductive system. This review aims at compiling the animal and plant based resources which bear promise of treating loss of libido and erectile dysfunction. A special emphasis is paid to find out scientific basis of their usage. The identification of potential resources could help undertake further studies to establish their possible mechanism of action; opening the doors to proper clinical trials for human use.