[Frontiers in Bioscience, Elite, 12, 95-101, Jan 1, 2020]

Atherosclerosis prevention: the role of special diets and functional food

Vasily P. Karagodin1, Vasily N. Sukhorukov2,3, Alexander N. Orekhov2,3, Shaw-Fang Yet4, Igor A. Sobenin2

1Plekhanov Russian University of Economics, Stremyanny Pereulok 36, 117997 Moscow, Russia, 2Institute of Human Morphology, Tsyurupa str. 3, 117418, Moscow, Russia, 3Institute of General Pathology and Pathophysiology, Baltiyskaya str. 8, 125315 Moscow, Russia, 4 Institute of Cellular and System Medicine, National Health Research Institutes, 35 Keyan Road, Zhunan Town, Miaoli County 35053, Taiwan R.O.C., 5Laboratory of Medical Genetics, National Medical Research Center of Cardiology, 15A 3-rd Cherepkovskaya Street, Moscow 121552, Russia


1. Abstract
2. Introduction
3. Nutrition and atherosclerosis
    3.1. Traditional foods and atherosclerosis
    3.2. Functional food and biologically active food supplements
4. Acknowledgment
5. References


Accumulating evidence highlight the importance of diet in the pathogenesis as well as prevention of atherosclerosis. In this review, we summarize the results of recent studies that demonstrate direct and indirect effects if functional foods and their analogues in prevention of initiation and progression of atherosclerosis. We discuss the epidemiological and clinical observations of such diets and dicuss their effects on the pathological mechanisms that drive atherosclerosis at cellular and molecular level.


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Abbreviations: FF: functional food, CVD: cardiovascular disease, LDL: low-density lipoproteins, HDL: high-density lipoproteins, PUFAs: omega-3 polyunsaturated fatty acids

Key Words: Functional foods, Atherosclerosis, Dietary supplements, Review

Send correspondence to: Vasily Karagodin, Plekhanov Russian University of Economics, Stremyanny Pereulok, 36, 117997 Moscow, Russia, Tel: 74956053551, E-mail: vpka@mail.ru