[Frontiers in Bioscience, Elite, 12, 95-101, Jan 1, 2020]

Atherosclerosis prevention: the role of special diets and functional food

Vasily P. Karagodin1, Vasily N. Sukhorukov2,3, Alexander N. Orekhov2,3, Shaw-Fang Yet4, Igor A. Sobenin2

1Plekhanov Russian University of Economics, Stremyanny Pereulok 36, 117997 Moscow, Russia, 2Institute of Human Morphology, Tsyurupa str. 3, 117418, Moscow, Russia, 3Institute of General Pathology and Pathophysiology, Baltiyskaya str. 8, 125315 Moscow, Russia, 4 Institute of Cellular and System Medicine, National Health Research Institutes, 35 Keyan Road, Zhunan Town, Miaoli County 35053, Taiwan R.O.C., 5Laboratory of Medical Genetics, National Medical Research Center of Cardiology, 15A 3-rd Cherepkovskaya Street, Moscow 121552, Russia

TABLE OF CONTENTS

1. Abstract
2. Introduction
3. Nutrition and atherosclerosis
    3.1. Traditional foods and atherosclerosis
    3.2. Functional food and biologically active food supplements
4. Acknowledgment
5. References

1. ABSTRACT

Accumulating evidence highlight the importance of diet in the pathogenesis as well as prevention of atherosclerosis. In this review, we summarize the results of recent studies that demonstrate direct and indirect effects if functional foods and their analogues in prevention of initiation and progression of atherosclerosis. We discuss the epidemiological and clinical observations of such diets and dicuss their effects on the pathological mechanisms that drive atherosclerosis at cellular and molecular level.

5. REFERENCES

1. E.M. Alissa, G.A. Ferns, Functional foods and nutraceuticals in the primary prevention of cardiovascular diseases. J Nutr Metab 2012:569486 (2012)
DOI: 10.1155/2012/569486
PMid:22570771 PMCid:PMC3335253

2. K. He, A. Merchant, E.B. Rimm, B.A. Rosner, M.J. Stampfer, W.C. Willett, A. Ascherio, Dietary fat intake and risk of stroke in male US healthcare professionals: 14 year prospective cohort study. BMJ 327:777-782 (2003)
DOI: 10.1136/bmj.327.7418.777
PMid:14525873 PMCid:PMC214078

3. K. Srinath Reddy, M.B. Katan, Diet, nutrition and the prevention of hypertension and cardiovascular diseases. Public Health Nutr 7:167-186 (2004)
DOI: 10.1079/PHN2003587

4. A.N. Orekhov, E.A. Ivanova, Introduction to the special issue "Atherosclerosis and Related Diseases". Vessel Plus 1:163-165 (2017)
DOI: 10.20517/2574-1209.2017.33

5. V.V. Sinyov, M.A. Sazonova, A.I. Ryzhkova, E.V. Galitsyna, A.A. Melnichenko, A.Y. Postnov, A.N. Orekhov, A.V. Grechko, I.A. Sobenin, Potential use of buccal epithelium for genetic diagnosis of atherosclerosis using mtDNA mutations. Vessel Plus 1:145-150 (2017)
DOI: 10.20517/2574-1209.2016.04

6. V.I. Alipov, V.N. Sukhorukov, V.P. Karagodin, A.V. Grechko, A.N. Orekhov, Chemical composition of circulating native and desialylated low density lipoprotein: what is the difference? Vessel Plus 1:107-115 (2017)
DOI: 10.20517/2574-1209.2017.20

7. P. Libby, Inflammation and cardiovascular disease mechanisms. Am J Clin Nutr 83:456S-460S (2006)
DOI: 10.1093/ajcn/83.2.456S
PMid:16470012

8. I. Tabas, Macrophage death and defective inflammation resolution in atherosclerosis. Nat Rev Immunol 10:36-46 (2010)
DOI: 10.1038/nri2675
PMid:19960040 PMCid:PMC2854623

9. M. Harangi, A. Szentpéteri, B. Nádró, H. Lőrincz, I. Seres, D. Páll, G. Paragh, HDL subfraction distribution and HDL function in untreated dyslipidemic patients. Vessel Plus 1:166-173 (2017)
DOI: 10.20517/2574-1209.2017.27

10. V.V. Tertov, V.V. Kaplun, I.A. Sobenin, E.Y. Boytsova, N.V. Bovin, A.N. Orekhov, Human plasma trans-sialidase causes atherogenic modification of low density lipoprotein. Atherosclerosis 159:103-115 (2001)
DOI: 10.1016/S0021-9150(01)00498-1

11. N.G. Nikiforov, K.O. Galstyan, L.V. Nedosugova, N.V. Elizova, K.I. Kolmychkova, E.A. Ivanova, Proinflammatory monocyte polarization in type 2 diabetes mellitus and coronary heart disease. Vessel Plus 1:192-195 (2017)
DOI: 10.20517/2574-1209.2017.21

12. A.N. Orekhov, V.V. Tertov, D.N. Mukhin, Desialylated low density lipoprotein--naturally occurring modified lipoprotein with atherogenic potency. Atherosclerosis 86:153-161 (1991)
DOI: 10.1016/0021-9150(91)90211-K

13. C. Weber, A. Zernecke, P. Libby, The multifaceted contributions of leukocyte subsets to atherosclerosis: lessons from mouse models. Nat Rev Immunol 8:802-815 (2008)
DOI: 10.1038/nri2415
PMid:18825131

14. T.V. Kirichenko, V.A. Myasoedova, A.N. Orekhov, Phytotherapy for the Prevention of Atherosclerosis-Associated Early Cerebral Ischemia, 2018, http://www.eurekaselect.com/node/160220/article
DOI: 10.2174/1389200219666180305151601
PMid:29512455

15. A.N. Orekhov, E.A. Ivanova, Editorial: Conventional, Traditional and Alternative Therapies for Cardiovascular Disorders. 2017, Part 3: Alternative Therapy, http://www.eurekaselect.com/node/149703/article, (2017)

16. T.V. Gorchakova, I.V. Suprun, I.A. Sobenin, A.N. Orekhov, Use of natural products in anticytokine therapy. Bull Exp Biol Med 143:316-319 (2007)
DOI: 10.1007/s10517-007-0099-6
PMid:18225751

17. A.N. Orekhov, A.V. Grechko, E.B. Romanenko, D.A. Chistiakov, Novel Approaches to Anti-Atherosclerotic Therapy: Cell-Based Models and Herbal Preparations (Review of Our Own Data), (2019) http://www.eurekaselect.com/node/168678/article
DOI: 10.2174/1570163816666190101112241
PMid:30621565

18. J.W.E. Moss, T.S. Davies, I. Garaiova, S.F. Plummer, D.R. Michael, D.P. Ramji, A Unique Combination of Nutritionally Active Ingredients Can Prevent Several Key Processes Associated with Atherosclerosis In vitro. PLoS One 11:e0151057-e0151057 (2016)
DOI: 10.1371/journal.pone.0151057
PMid:26950833 PMCid:PMC4780775

19. A. Mordente, B. Guantario, E. Meucci, A. Silvestrini, E. Lombardi, G.E. Martorana, B. Giardina, V. Bohm, Lycopene and cardiovascular diseases: an update. Curr Med Chem 18:1146-1163 (2011)
DOI: 10.2174/092986711795029717
PMid:21291369

20. H. Yanai, H. Adachi, A. Kawaguchi, M. Hakoshima, Y. Waragai, T. Harigae, Y. Masui, K. Kakuta, H. Hamasaki, H. Katsuyama, A. Sako, Тhe anti-atherosclerotic effects of tomatoes. Funct Foods Heal Dis 7:411-428 (2017)

21. P. Valderas-Martinez, C. Chiva-Blanch, R. Casas, S. Arranz, M. Martínez-Huélamo, M. Urpi-Sarda, X. Torrado, D. Corella, R.M. Lamuela-Raventós, R. Estruch, Tomato Sauce Enriched with Olive Oil Exerts Greater Effects on Cardiovascular Disease Risk Factors than Raw Tomato and Tomato Sauce: A Randomized Trial. Nutrients 8:170 (2016)
DOI: 10.3390/nu8030170
PMid:26999197 PMCid:PMC4808898

22. S.H. Johnsen, B.K. Jacobsen, S.K. Brækkan, J.-B. Hansen, E.B. Mathiesen, Fish consumption, fish oil supplements and risk of atherosclerosis in the Tromsø study. Nutr J 17:56 (2018)
DOI: 10.1186/s12937-018-0364-8
PMid:29801499 PMCid:PMC5970507

23. I.-J. Jensen, M. Walquist, B. Liaset, E.O. Elvevoll, K.-E. Eilertsen, Dietary intake of cod and scallop reduces atherosclerotic burden in female apolipoprotein E-deficient mice fed a Western-type high fat diet for 13 weeks. Nutr Metab (Lond) 13:8 (2016)
DOI: 10.1186/s12986-016-0068-z
PMid:26839578 PMCid:PMC4735963

24. C. Torris, M. Molin, M.C. Cvancarova, Lean fish consumption is associated with lower risk of metabolic syndrome: a Norwegian cross sectional study. BMC Public Health 16:347 (2016)
DOI: 10.1186/s12889-016-3014-0
PMid:27093865 PMCid:PMC4837629

25. M. Candela, I. Astiasarán, J. Bello, Deep-Fat Frying Modifies High-Fat Fish Lipid Fraction. J Agric Food Chem 46:2793-2796 (1998)
DOI: 10.1021/jf9709616

26. D. Mozaffarian, R.N. Lemaitre, L.H. Kuller, G.L. Burke, R.P. Tracy, D.S. Siscovick, Cardiac benefits of fish consumption may depend on the type of fish meal consumed: the Cardiovascular Health Study. Circulation 107:1372-1377 (2003)
DOI: 10.1161/01.CIR.0000055315.79177.16
PMid:12642356

27. J.B. Blumberg, A. Basu, C.G. Krueger, M.A. Lila, C.C. Neto, J.A. Novotny, J.D. Reed, A. Rodriguez-Mateos, C.D. Toner, Impact of Cranberries on Gut Microbiota and Cardiometabolic Health: Proceedings of the Cranberry Health Research Conference 2015. Adv Nutr 7:759S-770S (2016)
DOI: 10.3945/an.116.012583
PMid:27422512 PMCid:PMC4942875

28. J. Lietava, N. Beerova, S.V. Klymenko, E. Panghyova, I. Varga, O. Pechanova, Effects of Cornelian Cherry on Atherosclerosis and Its Risk Factors. Oxid Med Cell Longev 2019:2515270 (2019)
DOI: 10.1155/2019/2515270
PMid:30911343 PMCid:PMC6397968

29. V. Summerhill, V. Karagodin, A. Grechko, V. Myasoedova, A. Orekhov, Vasculoprotective Role of Olive Oil Compounds via Modulation of Oxidative Stress in Atherosclerosis. Front Cardiovasc Med 5:188 (2018)
DOI: 10.3389/fcvm.2018.00188
PMid:30622950 PMCid:PMC6308304

30. A.N. Orekhov, E.A. Ivanova, A.A. Melnichenko, I.A. Sobenin, Circulating desialylated low density lipoprotein. Cor Vasa 59:e149-e156 (2017)
DOI: 10.1016/j.crvasa.2016.10.003

31. D.M. Martirosyan, J. Singh, A new definition of functional food by FFC: what makes a new definition unique? Funct Foods Heal Dis 5:209-223 (2015)

32. J. Smith, E. Charter, F. Shahidi, Functional Food Product Development. Blackwell Publishing Ltd (2010)
DOI: 10.1002/9781444323351

33. S. Gyorgy, From techno-corporate food to alternative agri-food movements". Local Glob 4:112-140 (2007)

34. J. Kohler, D. Teupser, A. Elsasser, O. Weingartner, Plant sterol enriched functional food and atherosclerosis. Br J Pharmacol 174:1281-1289 (2017)
DOI: 10.1111/bph.13764
PMid:28253422 PMCid:PMC5429322

35. M. Franczyk-Zarow, R.B. Kostogrys, B. Szymczyk, J. Jawien, M. Gajda, T. Cichocki, L. Wojnar, S. Chlopicki, P.M. Pisulewski, Functional effects of eggs, naturally enriched with conjugated linoleic acid, on the blood lipid profile, development of atherosclerosis and composition of atherosclerotic plaque in apolipoprotein E and low-density lipoprotein receptor double-knockout mice (apoE/LDLR-/-) Br J Nutr 99:49-58 (2008)
DOI: 10.1017/S0007114507793893
PMid:17678565

36. L. Yueli, W. Liqun, W. Haitao, L. Lianbo, Y. Xinan, Comparison of anti-atherosclerotic effects of two different extracts from leaves of Mallotus furetianus. Asian Pac J Trop Med 4:878-882 (2011)
DOI: 10.1016/S1995-7645(11)60212-5

37. V.P. Karagodin, I.A. Sobenin, A.N. Orekhov, Antiatherosclerotic and Cardioprotective Effects of Time-Released Garlic Powder Pills. Curr Pharm Des 22:196-213 (2016)
DOI: 10.2174/1381612822666151112153351

38. A.N. Orekhov, Anti-atherosclerotic Drugs from Natural Products. Nat Prod Chem Res 1 (2013)
DOI: 10.4172/2329-6836.1000121

Abbreviations: FF: functional food, CVD: cardiovascular disease, LDL: low-density lipoproteins, HDL: high-density lipoproteins, PUFAs: omega-3 polyunsaturated fatty acids

Key Words: Functional foods, Atherosclerosis, Dietary supplements, Review

Send correspondence to: Vasily Karagodin, Plekhanov Russian University of Economics, Stremyanny Pereulok, 36, 117997 Moscow, Russia, Tel: 74956053551, E-mail: vpka@mail.ru