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Desmosomes are junctional complexes that are formed among opposing plasma membranes. In some instances, however, the hemi-demosomes are formed between the epithelial cells and the basal lamina of the epithelium. These can be found between the interdigitating cellular bridges in squamous cell carcinomas (green arrowheads) as well as in adenocarcinomas. Each desmosome consists of an electron dense plate immediately underneath the plasma membrane (blue arrowheads) where tonofilaments converge (red arrowheads). The space between the plasma membranes, normally is 250 angstrom in width and is filled with electron dense material (browh arrowhead)
| Low Power; Desmosome |
High Power; Desmosome |
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