Normocytic normochromic anemia
Elevated serum erythrocyte sedimentation rate
Elevated serum calcium level
Elevated serum urate level
Elevated blood urea nitrogen level
Elevated serum creatinine level
Elevated serum alkaline phosphatase level
Rouleau formation of red blood cells on peripheral smear
Proteinuria
Glycosuria
Total serum protein level elevated
Bence jones proteinuria
Serum protein electrophoresis (SPEP)
Monoclonal spike in beta or gamma globulin region
Immunoelectrophoresis of urine (monoclonal paraprotein, IgG or IgA paraprotein
Radiography of skull, ribs, and spine (round, oval, and punched out osteolytic lesions, pathological fractures, and osteopenia)
Isotope scanning
C.T. scan