FRONTIERS IN BIOSCIENCE;

DATA FORM FOR CANCER STAGING - BREAST





Form # 785-1-037

CLIN PATH DEFINITIONS
    PRIMARY TUMOR (T)

TX Primary tumor cannot be assessed

T0 No evidence of primary tumor

Tis Carcinoma in situ: Intraductal carcinoma, lobular carcinoma in situ, or Paget's disease of the nipple with no tumor

T1 Tumor 2 cm or less in greatest dimension

T1a   0.5 cm or less in greatest dimension

T1b   More than 0.5 cm but not more than 1 cm in greatest dimension

T1c   More than 1 cm but not more than 2 cm in greatest dimension

T2 Tumor more than 2 cm but not more than 5 cm in greatest dimension

T3 Tumor more than 5 cm in greatest dimension

T4 Tumor of any size with direct extension to chest wall or skin

T4a   Extension to chest wall

T4b   Edema (including peau d'orange) or ulceration of the skin of breast or satellite skin nodules confined to same breast

T4c   Both T4a and T4b

T4d   Inflammatory carcinoma
    LYMPH NODE (N)

NX Regional lymph nodes cannot be assessed (e.g. previously removed)

N0 No regional lymph node metastasis

N1 Metastasis to movable ipsilateral axillary lymph node(s)

N2 Metastasis to ipsilateral axillary lymph node(s) fixed to one another or to other structures

N3 Metastasis to ipsilateral internal mammary lymph node(s)
    PATHOLOGIC CLASSIFICATION (PN)

PNX Regional lymph nodes cannot be assessed (e.g. previously removed, or not removed for pathologic study)

pN0 No regional lymph node metastasis

pN1 Metastasis to movable ipsilateral axillary lymph node(s)

  pN1a Only micrometastasis (none larger than 0.2 cm)

  pN1b Metastasis to lymph nodes, any larger than 0.2 cm

  pN1bi Metastasis in 1 to 3 lymph nodes, any more than 0.2 cm and all less than 2 cm in greatest dimension

  pN1bii Metastasis to 4 or more lymph nodes, any more than 0.2 cm and all less than 2 cm in greatest dimension

  pN1biii Extension of tumor beyond the capsule of a lymph node metastasis less than 2 cm in greatest dimension

  pN1biv Metastasis to a lymph node 2 cm or more in greatest dimension

pN2 Metastasis to ipsilateral axillary lymph nodes that are fixed to one another or to other structures

pN3 Metastasis to ipsilateral internal mammary lymph node(s)
    DISTANT METASTASIS (M)

MX Presence of distant metastasis cannot be assessed

M0 No distant metastasis

M1 Distant metastasis (includes metastasis to ipsilateral supraclavicular lymph node(s)

Pathologic Stage by: M.D. Date:

CLIN PATH STAGE GROUPING

0 Tis N0 M0

I T1 N0 M0

IIA T0 N1 M0
      T1 N1* M0
      T2 N0 M0

IIB T2 N1 M0
      T3 N0 M0

IIIA T0 N2 M0
      T1 N2 M0
      T2 N2 M0
      T3 N1 M0
      T3 N2 M0

IIIB T4 Any N M0
      Any T N3 M0

IV Any T Any N M1

*Note: The prognosis with pN1a is similar to that of patients with pN0.

Attending: M.D. Date:

THE FINAL STAHE GROUPNG (CLINICAL & PATHOLOGICAL) IS THE RESPONSIBILITY OF THE ATTENDING PHYSICIAN.

Comments:

Patient Name: