FRONTIERS IN BIOSCIENCE;

DATA FORM FOR CANCER STAGING - NEPHROBLASTOMA





Form # 785-1-056

CLIN PATH DEFINITIONS
    PRIMARY TUMOR (T)

TX Primary tumor cannot be assessed

T0 No evidence of primary tumor

T1 Unilateral tumor 80 cm2 or less in area (including kidnes)*

T2 Unilateral tumor more than 80 cm2 in area (including kidney)*

T3 Unilateral tumor rupture before treatment

T4 Bilateral tumors
    *Note: The area is calculated by multiplying the vertical and horizontal dimensions of the radiologic shadow of the tumor and kidney.
    LYMPH NODE (N)

NX Regional lymph nodes cannot be assessed

N0 No regional lymph node metastasis

N1 Regional lymph node metastasis
    DISTANT METASTASIS (M)

MX Presence of distant metastasis cannot be assessed

M0 No distant metastasis

M1 Distant metastasis
    PRIMARY TUMOR (PT)

pTX Primary tumor cannot be assessed

pT0 No evidence of primary tumor

pT1 Intrarenal tumor completely encapsulated; excision complete and margins histologically free

pT2 Tumor invades beyond the capsule or renal parenchyma;* excision complete

pT3 Tumor invades beyond the capsule or renal parenchyma;* excision incomplete or preoperative or operative rupture

pT3a   Microscopic residual tumor limited to tu mor bed

pT3b   Macroscopicresidual tumor or spillage or malignant as cites

pT3c   Surgical exploration only, tumor not resected

pT4 Bilateral tumors

*Note: This includes breach of the renal capsule or tumor seen microscopically outside the capsule; tumor adhesions microscopically confirmed; infiltrations of or tumor thrombus within the renal vessels outside the kidney; and infiltration of the renal pelvis and/or ureter, peripelvic, and pericalyceal fat.
    LYMPH NODE (PN)

pNX Regional lymph nodes cannot be assessed
    pN0 No regional lymph node metastasis
    pN1 Regional lymph node metastasis

pN1a   Regional lymph node metastasis completely resected

PN1b   Regional lymph node metastasis incompletely resected
    DISTANT METASTASIS (PM)

pMX Presence of distant metastasis cannot be assessed

pM0 No distant metastasis

pM1 Distant metastasis

Pathologic Stage by: M.D. Date:  

THE FINAL STAGE GROUPING (CLINICAL & PATHOLOGICAL) IS THE RESPONSIBILITY OF THE ATTENDING PHYSICIAN.

CLIN PATH CLINICAL STAGE GROUPING (cTNM)

I T1 N0 M0

II T2 N0 M0

III T1 N1 M0
      T2 N1 M0
      T3 Any N M0

IVA T1 Any N M1
      T2 Any N M1
      T3 Any N M1

IVB T4 Any N Any M
    Pathologic Stage Grouping (pTNM)

I pT1 pN0 M0

II pT1 pN1a M0
      pT2 pN0 M0
      pT2 pN1a M0

IIIA pT3a pN0 M0
      pT3a pN1a M0

IIIB pT1 pN1b M0
      pT2 pN1b M0
      pT3a pN1b M0
      pT3b Any pN M0
      pT3c Any pN M0

IVA pT1 Any pN M1
      pT2 Any pN M1
      pT3a Any pN M1
      pT3b Any pN M1
      pT3c Any pN M1

IVB pT4 Any pN Any M

Attending: M.D. Date

Comments:

Patient Name: