Managing Editor: Andrej Romanovsky
Systemic Inflammation Laboratory
Principal Investigator
Andrej A. Romanovsky, MD, PhD
URL: http://www.IChoseStJoes.com/Fever
Brief Overview
The Systemic Inflammation Laboratory is a basic research unit within the Trauma Research Program (Director, Dr. S. R. Petersen) of St. Joseph’s Hospital in Phoenix, Arizona. It is also a part of the Neuroscience Research Center of the Barrow Neurological Institute. The laboratory was created as the Trauma Metabolic Laboratory in 1986. During 1986-1999, it was directed by Dr. M. Jeevanandam and focused on the metabolic consequences of trauma disease. Since December 1999, the laboratory is headed by Dr. A. A. Romanovsky, previously Director of Thermoregulation Laboratory at Clinical Research and Technology Center, Legacy Health System, in Portland, Oregon.
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 TABLE OF CONTENTS
Fever and hypothermia in systemic inflammation: recent discoveries and revisions
Andrej A. Romanovsky, Maria C. Almeida, David M. Aronoff, Andrei I. Ivanov, Jan P. Konsman, Alexandre A. Steiner, and Victoria F. Turek
[Frontiers in Bioscience 10, 2193-2216, September 1, 2005]
Signaling the brain in systemic inflammation: the role of perivascular cells
Jennifer C. Schiltz and Paul E. Sawchenko
[Frontiers in Bioscience 8, s1321-1329, September 1, 2003]
Fever and anapyrexia in systemic inflammation: intracellular signaling by cyclic nucleotides
Alexandre A. Steiner and Luiz G. S. Branco
[Frontiers in Bioscience 8, s1398-1408, September 1, 2003]
Signaling the brain in systemic inflammation: role of sensory circumventricular organs
Joachim Roth, Eva-Maria Harré, Christoph Rummel, Rüdiger Gerstberger &Thomas Hübschle
[Frontiers in Bioscience 9, 290-300, January 1, 2004]
Cholecystokinin: possible mediator of fever and hypothermia
Zoltán Szelényi, Miklós Székely, Zoltán Hummel, Márta Balaskó, Andrej A. Romanovsky and Erika Pétervári
[Frontiers in Bioscience 9, 301-308, January 1, 2004]
Angiotensin II: its effects on fever and hypothermia in systemic inflammation
Tatsuo Watanabe, Michio Miyoshi and Toshiaki Imoto
[Frontiers in Bioscience 9, 438-447, January 1, 2004]
Signaling the brain in the early sickness syndrome: are sensory nerves involved?
Andrej A. Romanovsky
[Frontiers in Bioscience 9, 494-504, January 1, 2004]
Endogenous antipyretics: neuropeptides and glucocorticoids
Joachim Roth, Eugen Zeisberger, Stanislav Vybíral and Ladislav Janský
[Frontiers in Bioscience 9, 816-826, January 1, 2004]
Signaling the brain in systemic inflammation: the role of complement
Clark M. Blatteis, Shuxin Li, Zhonghua Li, Vit Perlik, and Carlos Feleder
[Frontiers in Bioscience 9, 915-931, January 1, 2004]
Antipyretic therapy
Regina Botting
[Frontiers in Bioscience 9, 956-966, January 1, 2004]
Fever in systemic inflammation: roles of purines
Alexander V. Gourine, Nicholas Dale, Valery N. Gourine, and K. Michael Spyer
[Frontiers in Bioscience 9, 1011-1022, January 1, 2004]
Cytokines and fever
Bruno Conti, Iustin Tabarean, Cristina Andrei and Tamas Bartfai
[Frontiers in Bioscience 9, 1433-1449, May 1, 2004]
Hypothermia in systemic inflammation: role of cytokines
Lisa R. Leon
[Frontiers in Bioscience 9, 1877-1888, May 1, 2004]
Prostaglandin E2 as a mediator of fever: synthesis and catabolism
Andrei I. Ivanov and Andrej A. Romanovsky
[Frontiers in Bioscience 9, 1977-1993, May 1, 2004]
The febrile patient: diagnostic, prognostic and therapeutic considerations
Philip A. Mackowiak
[Frontiers in Bioscience 9, 2297-2301, September 1, 2004]
Sickness behavior in fever an hypothermia
Zoltan Szelenyi and Miklos Szekely
[Frontiers in Bioscience 9, 2447-2456, September 1, 2004]
Orexigenic vs. anorexigenic peptides and feeding status in the modulation of fever and hypothermia
Miklos Szekely, Erika Petervari and Zoltan Szelenyi
[Frontiers in Bioscience 9, 2746-2763, September 1, 2004]
Signaling the brain in inflammation: the role of endothelial cells
Kiyoshi Matsumura and Shigeo Kobayashi
[Frontiers in Bioscience 9, 2819-2826, September 1, 2004]
Prostaglandin E2 as a mediator of fever: the role of prostaglandin E (EP) receptors
Takakazu Oka
[Frontiers in Bioscience 9, 3046-3057, September 1, 2004]
Thermal homeostasis in systemic inflammation: modulation of neuronal mechanisms
Ladislav Jansky and Stanislav Vybiral
[Frontiers in Bioscience 9, 3068-3084, September 1, 2004]
Non-prostaglandin eicosanoids in fever and anapyrexia
Wieslaw Kozak and Vadim Fraifeld
[Frontiers in Bioscience 9, 3339-3355, September 1, 2004]
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