FRONTIERS IN BIOSCIENCE PRESENTS

THE SPECIAL ISSUE


GENETICALLY-MODIFIED ANIMALS AS RESEARCH MODELS IN DEVELOPMENT AND DISEASE

Managing Editor: Vicente Andrés

  

 
TABLE OF CONTENTS

Transcriptional profiling of early onset diet-induced atherosclerosis in apolipoprotein E-deficient mice
Claudia Castro, Josep María Campistol, Domingo Barettino, and Vicente Andrés

[Frontiers in Bioscience 10, 1932-1945, May 1, 2005]

Vitamin D and cancer: an update of in vitro and in vivo data
Paloma Ordonez-Moran, Maria Jesus Larriba, Natalia Pendas-Franco, Oscar Aguilera, Jose Manuel Gonzalez-Sancho, and Alberto Munoz

[Frontiers in Bioscience 10, 2723-2749, September 1, 2005]

The plasminogen activation system in skeletal muscle regeneration: antagonistic roles of urokinase-type plasminogen activator (upa) and its inhibitor (PAI-1)
Monica Suelves, Berta Vidal , Vanessa Ruiz, Bernat Baeza-Raja, Angels Diaz-Ramos, Isabel Cuartas, Frederic Lluis, Maribel Parra, Merce Jardi, Roser Lopez-Alemany, Antonio L. Serrano, and Pura Munoz-Canoves

[Frontiers in Bioscience 10, 2978-2985, September 1, 2005]

Stem cells for cardiac repair: state of the art
Gianluigi Condorelli and Cesare Peschl

[Frontiers in Bioscience 10, 3143-3150, September 1, 2005]

Controlled gene activation and inactivation in the mouse
Moisés Mallo

[Frontiers in Bioscience 11, 313-327, January 1, 2006]

Endometriosis: harmful survival of an ectopic tissue
Janos Garai, Valeria Molnar, Tamas Varga, Miklos Koppan, Attila Torok, and Jozsef Bodis

[Frontiers in Bioscience 11, 595-619, January 1, 2006]

New animal models to study the role of tyrosinase in normal retinal development
Alfonso Lavado, and Lluis Montoliu

[Frontiers in Bioscience 11, 743-752, January 1, 2006]

Understanding the role of dietary components on atherosclerosis using genetic engineered mouse models
Alfonso J. Sarria, Joaquin C. Surra, Sergio Acin, Ricardo Carnicer, Maria A. Navarro, Jose M. Arbones-Mainar, Natalia Guillen, Maria V. Martinez-Gracia, Carmen Arnal and Jesus Osada

[Frontiers in Bioscience 11, 955-967, January 1, 2006]

Mammalian genome targeting using site-specific recombinases
Angel-Luis García-Otín 1 and Florian Guillou

[Frontiers in Bioscience 11, 1108-1136, January 1, 2006]

Cyclins and CDKS in development and cancer: lessons from genetically modified mice
David Santamaria and Sagrario Ortega

[Frontiers in Bioscience 11, 1164-1188, January 1, 2006]

Antiatherogenic role of high-density lipoproteins: insights from genetically engineered-mice
Joan Carles Escola-Gil Laura Calpe-Berdiel, Xavier Palome, Vicent Ribas, Jordi Ordonez-Llanos and Francisco Blanco-Vaca

Antiatherogenic role of HDL in genetically engineered mice [Frontiers in Bioscience 11, 1328-1348, May 1, 2006]

Atheroma development in apolipoprotein E-null mice is not affected by partial inactivation of PTEN
Vicente Andrés , Marisol Gascón-Irún , Pier Paolo Pandolfi, and Herminia González-Navarro

[Frontiers in Bioscience 11, 2739-2745, September 1, 2006]

Cyclooxygenase 2: understanding the pathophysiological role through genetically altered mouse models
Paloma Martin Sanz, Sonsoles Hortelano, Lisardo Bosca and Marta Casado

[Frontiers in Bioscience 11, 2876-2888, September 1, 2006]

Cell Fusion: biological perspectives and potential for regenerative medicine
Manuel Alvarez-Dolado

[Frontiers in Bioscience 12, 1-12, January 1, 2007]

Animal models for the study of liver regeneration: role of nitric oxide and prostaglandins
Sonsoles Hortelano, Miriam Zeini, Marta Casado, Paloma Martín-Sanz and Lisardo Boscá

[Frontiers in Bioscience 12, 13-21, January 1, 2007]

Genetically engineered mice as a model for studying cardiac arrhythmias
Juan Tamargo, Ricardo Caballero, Lucía Núñez, Ricardo Gómez, Miguel Vaquero and Eva Delpón

[Frontiers in Bioscience 12, 22-38, January 1, 2007]

Age-related Cardiac Deterioration: insights from Drosophila
Robert J. Wessells and Rolf Bodmer

[Frontiers in Bioscience 12, 39-48, January 1, 2007]

The risk for cardiovascular disease in women: from estrogens to selective estrogen receptor modulators
Antonio Cano, Carlos Hermenegildo, Pilar Oviedo, and Juan J. Tarín

[Frontiers in Bioscience 12, 49-68, January 1, 2007]

The GCK II and III subfamilies of the STE20 group kinases
Celia María Pombo, Thomas Force, John Kyriakis, Emilio Nogueira, Miguel Fidalgo, and Juan Zalvide

[Frontiers in Bioscience 12, 850-859, January 1, 2007]

Type-2 Diabetic Leprdb/db Mice Show a Defective Microvascular Phenotype under basal conditions and an Impaired Response to Angiogenesis Gene Therapy in the setting of Limb Ischemia
Costanza Emanueli, rea Caporali, Nicolle Krankel, Brunella Cristofaro, Sophie Van Linthout, Paolo Madeddu

[Frontiers in Bioscience 12, 2003-2012, January 1, 2007]

Plasma insulin levels predict the development of atherosclerosis when IRS2 deficiency is combined with severe hypercholesterolemia in apolipoprotein E-null mice
Herminia Gonzalez-Navarro, Marian Vila-Caballer, Maria F. Pastor, Angela Vinue, Morris F. White, Deborah Burks, Vicente Andres

[Frontiers in Bioscience 12, 2291-2298, January 1, 2007]

Yeast as a model system to study glucose-mediated signalling and response
Pascual Sanz

[Frontiers in Bioscience 12, 2358-2371, January 1, 2007]

An insight into the pathophysiology of thrombosis in antiphospholipid syndrome
Ivan G Palomo 1, Fabian M Segovia 1, Marcelo L Alarcon 1, Barbara Y Fuentes 1, Jaime G Pereira 2, Armando Rojas 3, Ricardo Forastiero 4

[Frontiers in Bioscience 12, 3093-3103, May 1, 2007]

Retromer and sorting nexins in development
Marcel Verges

[Frontiers in Bioscience 12, 3825-3851, May 1, 2007]

Genetically-engineered animals as research models for atherosclerosis : their use for the characterization of PPAR agonists in the treatment of cardiometabolic disorders
Catherine Fievet, Jean-Charles Fruchart , Bart Staels

[Frontiers in Bioscience 12, 4132-4156, May 1, 2007]

Potential contribution of bone marrow-derived precursors to vascular repair and lesion formation: lessons from animal models of vascular diseases
Hiroshi Iwata, Masataka Sata

[Frontiers in Bioscience 12, 4157-4167, May 1, 2007]

Murine models to investigate the influence of diabetic metabolism on the development of atherosclerosis and restenosis
Herminia Gonzalez-Navarro, Deborah J. Burks, Vicente Andres

[Frontiers in Bioscience 12, 4439-4455, May 1, 2007]

Protein isoprenylation in biology and disease: general overview and perspectives from studies with genetically engineered animals
Dolores Perez-Sala

[Frontiers in Bioscience 12, 4456-4472, May 1, 2007]

Of mice without pockets: mouse models to study the function of Rb family proteins
Anxo Vidal, Carmen Carneiro, Juan B. Zalvide

[Frontiers in Bioscience 12, 4483-4496, May 1, 2007]

Function and regulation of the complement system in cardiovascular diseases
Riina Oksjoki, Petri T. Kovanen, Seppo Meri, Markku O. Pentikainen

[Frontiers in Bioscience 12, 4696-4708, May 1, 2007]

Role of Bcl-2 family members on apoptosis: what we have learned from knock-out mice
Ramon Roset, Laura Ortet, Gabriel Gil-Gomez

[Frontiers in Bioscience 12, 4722-4730, May 1, 2007]

HIV-1 transgenic expression in mice induces selective atrophy of fast-glycolytic skeletal muscle fibers
Antonio L. Serrano, Merce Jardi, Monica Suelves, Paul E. Klotman, Pura Munoz-Canoves

[Frontiers in Bioscience 13, 2797-2805, January 1, 2008]

Knock-out mouse models of proprotein convertases: unique functions or redundancy?
John W.M. Creemers , Abdel-Majid Khatib

[Frontiers in Bioscience 4960-4971, May 1, 2008]

Control of atherosclerotic plaque vulnerability: Insights from transgenic mice
Sylvia Heeneman, Esther Lutgens, Kitty B. Schapira, Mat J.A.P. Daemen, Erik A.L. Biessen

[Frontiers in Bioscience 13, 6289-6313, May 1, 2008]

The use of genetically engineered model systems for research on human aging
Guenter Lepperdinger, Peter Berger, Michael Breitenbach, Kai-Uwe Frohlich, Johannes Grillari, Beatrix Grubeck-Loebenstein, Frank Madeo, Nadege Minois, Werner Zwerschke, Pidder Jansen-Durr

[Frontiers in Bioscience 13, 7022-7031, May 1, 2008]