Pathology, molecular diagnosis and prognostic markers

Expression microarray analysis of brain tumors: what have we learned so far
Stephen B. Hunter, Carlos S. Moreno
[Frontiers in Bioscience 7, c74-82, August 1, 2002]

Proteomics in primary brain tumors
Ping-pin Zheng, Johan M. Kros, Peter A.E. Sillevis-Smitt, Theo M. Luider
[Frontiers in Bioscience 8, d451-463, January 1, 2003]

Ancillary FISH analysis for 1p AND 19q status: preliminary observations in 287 gliomas and oligodendroglioma mimics
Arie Perry, Christine E. Fuller, Ruma Banerjee, Daniel J. Brat, Bernd W. Scheithauer
[Frontiers in Bioscience 8, a1-9, January 1, 2003]

Correlation of molecular genetic analysis of P53, MDM2, P16, PTEN, and EGFR and survival of patients with anaplastic astrocytoma and glioblastoma
Yukitaka Ushio, Kenji Tada, Shoji Shiraishi, Takanori Kamiryo, Naoki Shinojima, Masato Kochi, Hideyuki Saya
[Frontiers in Bioscience 8, e281-288, May 1, 2003]

Genes and genetics

Genetic alterations in adult diffuse glioma: occurrence, significance, and prognostic implications
Justin S. Smith and Robert B. Jenkins
[Frontiers in Bioscience 5, d213-231 January 1, 2000]

DNA methylation in brain development and gliomagenesis
Joseph F. Costello
[Frontiers in Bioscience 8, s175-184, January 1, 2003]

Genetic and signaling pathway alterations in glioblastoma: relevance to novel targeted therapies
Ravi D. Rao, Joon H. Uhm, Sunil Krishnan, and C David James
[Frontiers in Bioscience 8, e270-280, May 1, 2003]

Cell biology, apoptosis, growth factors and signaling

Apoptosis in gliomas, and its role in their current and future treatment
Oliver Bögler and Michael Weller
[Frontiers in Bioscience 7, e339-353, August 1, 2002]

The role of transforming growth factor-beta in primary brain tumors
Jeremy N. Rich
[Frontiers in Bioscience 8, e245-260, January 1, 2003]

Immunology and immunotherapy

Detection of TNF inhibithors (soluble receptors) in the sera and tumor cyst fluid of patients with malignant astrocytomas of the brain
Mario Ammirati , Sanjay Rao, and Gale Granger
[Frontiers in Bioscience 6, b17-24, October 1, 2001]

CpG-oligonucleotides for cancer immunotherapy : review of the literature and potential applications in malignant glioma
Antoine F. Carpentier, Gregor Auf and Jean-Yves Delattre
[Frontiers in Bioscience 8, e115-127, January 1, 2003]

Cellular immunity and immunotherapy of brain tumors
Robert M. Prins and Linda M. Liau
[Frontiers in Bioscience 9, 3124-3136, September 1, 2004]

Angiogenesis and invasion

Genetic modulation of hypoxia induced gene expression and angiogenesis: relevance to brain tumors
Daniel J. Brat, Balveen Kaur, Erwin G. Van Meir
[Frontiers in Bioscience 8, d100-116, January 1, 2003]

Neoangiogenesis in human astrocytomas: expression and functional role of angiopoietins and their cognate receptors
Gelareh Zadeh, Abhijit Guha
[Frontiers in Bioscience 8, e128-137, January 1, 2003]

The role of integrins in the malignant phenotype of gliomas
Joon H. Uhm, Candece L. Gladson, & Jasti S. Rao
[Frontiers in Bioscience 4, d188-199, February 15, 1999]

Biological significance of the expression of urokinase-type plasminogen activator receptors (uPARs) in brain tumors
Sanjeeva Mohanam, Candece L. Gladson, Chilukuri N. Rao1 and Jasti S. Rao
[Frontiers in Bioscience 4, d178-187, February 15, 1999]

Invasion of human glioma: Role of extracellular matrix proteins
S. K. Chintala and J. S. Rao
[Vol 1 pp d324-339; November 1, 1996]

Mechanisms of tumor cell invasion and angiogenesis in the central nervous system
Therese Visted, Per Oyvind Enger, Morten Lund-Johansen and Rolf Bjerkvig
[Frontiers in Bioscience 8, e289-304, May 1, 2003]

The role of matrix metalloproteinases in glioma invasion
Mitsutoshi Nakada, Yasunori Okada, Junkoh Yamashita
[Frontiers in Bioscience 8, e261-269, January 1, 2003]

Models for Animal and human brain cell transformation

Defined human cellular systems in the study of glioma development
Russell O. Pieper
[Frontiers in Bioscience 8, s19-27, January 1, 2003]

Angiogenesis and its role in the behavior of astrocytic brain tumors
Shirley I. Stiver
[Frontiers in Bioscience 9, 3105-3123, September 1, 2004]

Experimental therapeutics

Oncolytic viruses for the therapy of brain tumors and other solid malignancies: a review
Giulia Fulci and Ennio Antonio Chiocca
[Frontiers in Bioscience 8, e346-360, May 1, 2003]

Oncolytic adenoviruses for malignant glioma therapy
Hong Jiang, Charles Conrad, Juan Fueyo, Candelaria Gomez-Manzano, Ta-Jen Liu
[Frontiers in Bioscience 8, d577-588, May 1, 2003]

Efficacy of adenoviral p53 delivery with SCH58500 in the intracranial 9L and RG2 models
Geoffrey Bowers, Ju He, Karl Schulz, Gregory Olivarria, Dan Maneval, Jeffrey J. Olson
[Frontiers in Bioscience 8, a54-61, May 1, 2003]

Combination of epidermal growth factor receptor targeted therapy with radiation therapy for malignant gliomas
Sunil Krishnan, Ravi D. Rao, C. David James and Jann N. Sarkaria
[Frontiers in Bioscience 8, e1-13, 2003]

Targeted therapy of brain tumors utilizing neural stem and progenitor cells
Michael J. Burns and William Weiss
[Frontiers in Bioscience 8, e228-234, January 1, 2003]

Medical therapeutics, surgery and pharmacology

Radiation therapy and radiobiology

UV-ozone ashing of cells and tissues for spatially resolved trace element analysis
B. Gilbert, L. Perfetti, R. Hansen, D. Mercanti, M. T. Ciotti, P. Casalbore, R. Andres, P. Perfetti, G. Margaritondo and Gelsomina De Stasio
[Frontiers in Bioscience, 5, a10-17, May 1, 2000]

Epidemiology

Polyomaviruses and human tumors: a brief review of current concepts and interpretations
John A. Lednicky and Janet S. Butel
[Frontiers in Bioscience 4, d153-164, February 15, 1999]

Quality of life