FRONTIERS IN BIOSCIENCE PRESENTS

THE SPECIAL ISSUE


ADVANCES IN CHEMICAL, BIOCHEMICAL, AND BIOMEDICAL PRINCIPLES AND APPLICATIONS OF NUCLEOSIDES, NUCLEOTIDES, AND POLYNUCLEOTIDES

Managing Editor: Ramachandra Hosmane

  

 
TABLE OF CONTENTS

Understanding the molecular mechanism of drug resistance of anti-HIV nucleosides by molecular modeling
Youhoon Chong and Chung K. Chu

[Frontiers in Bioscience 9, 164-186, January 1, 2004]

Preparation of interstrand cross-linked DNA oligonucleotide duplexes
David M. Noll, Anne M. Noronha, Christopher J. Wilds and Paul S. Miller

[Frontiers in Bioscience 9, 421-437, January 1, 2004]

Cyclosal-pronucleotides - development of first and second generation chemical trojan horses for antiviral chemotherapy
Chris Meier, Astrid Meerbach and Jan Balzarini

[Frontiers in Bioscience 9, 873-890, January 1, 2004]