COMPUTATIONS OF THE STRUCTURES OF PROTEINS AND NUCLEIC ACIDS AND IMPLICATIONS FOR DRUG DESIGN
Managing Editor:Mathew Pincus

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TABLE OF CONTENTS
Computational protein chemistry of p53 and p53 peptides
Paul W. Brandt-Rauf, Ramon V. Rosal, Robert L. Fine and Matthew R. Pincus
[Frontiers in Bioscience 9, 2778-2787, September 1, 2004]
Structure-based development of a novel collagen inhibitor for MMP-1: re-designing the functions of a matrix protein
James M Chen and Li-An Yeh
[Frontiers in Bioscience 9, 2788-2795, September 1, 2004]
Molecular modeling of mammalian cytochrome P450s
Fred K. Friedman, Richard C. Robinson and Renke Dai
[Frontiers in Bioscience 9, 2796-2806, September 1, 2004]
Conformational searches elucidate effects of stereochemistry on structures of deoxyadenosine covalently bound to tumorigenic metabolites of benzo[C] phenanthrene
Min Wu, S. Frank Yan, Jian Tan, Dinshaw J. Patel, Nicholas E. Geacintov and Suse Broyde
[Frontiers in Bioscience 9, 2807-2818, September 1, 2004]
The protein folding problem: global optimization of force fields
H. A. Scheraga, A. Liwo, S. Oldziej, C. Czaplewski, J. Pillardy, D. R. Ripoll, J. A. Vila, R. Kazmierkiewicz, J. A. Saunders, Y. A. Arnautova, A. Jagielska, M. Chinchio, and M. Nanias
[Frontiers in Bioscience 9, 3296-3323, September 1, 2004]
Development of new anti-cancer peptides from conformational energy analysis of the oncogenic ras-p21 protein and its complexes with target proteins
Matthew R. Pincus
[Frontiers in Bioscience 9, 3486-3509, September 1, 2004]
Two dual specificity kinases are preferentially induced by wild-type rather than by oncogenic RAS-P21 in Xenopus oocytes
Yongxia Qu, Victor Adler, Tearina Chu, Ovidu Platica, Josef Michl, Sidney Pestka, Lara Izotova, Mohamed Boutjdir and Matthew R. Pincus
[Frontiers in Bioscience 11, 2420-2427, September 1, 2006]
The dual-specificity kinases, TOPK and DYRK1A, are critical for oocyte maturation induced by wild-type-but not by oncogenic- ras-p21 protein
Yongxia Qu, Victor Adler, Lara Izotova, Sidney Pestka, Wilbur Bowne, Josef Michl, Mohamed Boutjdir, Fred K. Friedman, Matthew R. Pincus
[Frontiers in Bioscience 12, 5089-5097, September 1, 2007]
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