FRONTIERS IN BIOSCIENCE PRESENTS

THE SPECIAL ISSUE


HEPATIC FIBROSIS AND TARGETING THERAPY

Managing Editors: Jian Wu and Pamela A. Norton

  

 
TABLE OF CONTENTS

Section I: Pathogenesis of Hepatic Fibrosis and Therapy

Activation of hepatic stellate cells - a key issue in liver fibrosis
Helen L Reeves and Scott L Friedman

[Frontiers in Bioscience 7, d808-826, April 1, 2002]

Roles of TGF-beta in hepatic fibrosis
A. M. Gressner, R. Weiskirchen, K. Breitkopf, S. Dooley

[Frontiers in Bioscience 7, d793-807, April 1, 2002]

PDGF and signal transduction in hepatic stellate cells
Massimo Pinzani

[Frontiers in Bioscience 7, d1720-1726, August 1, 2002]

Peribiliary myofibroblasts in biliary type liver fibrosis
Nils Kinnman and Chantal Housset

[Frontiers in Bioscience 7, d496-503, Feburary 1, 2002]

Chemokines in liver inflammation and fibrosis
Fabio Marra

[Frontiers in Bioscience 7, d1899-1914, September 1, 2002]

Homeostasis of extracellular matrix by TGF-beta and lefty
Siamak Tabibzadeh

[Frontiers in Bioscience 7, d1231-1246, May 1, 2002]

Retinoids in liver fibrosis and cancer
Masataka Okuno, Soichi Kojima, Kuniharu Akita1, Rie Matsushima-Nishiwaki, Seiji Adachi, Tetsuro Sano, Yukihiko Takano, Koji Takai, Akihiro Obora, Ichiro Yasuda, Yoshimune Shiratori, Yukio Okano, Jun Shimada, Yasuhiro Suzuki, Yasutoshi Muto1 and Hisataka Moriwaki
[Frontiers in Bioscience 7, d204-218, January 1, 2002]

NF-KAPPA B, liposomes and pathogenesis of hepatic injury and fibrosis
Jian Wu and Mark A. Zern

[Frontiers in Bioscience 4, d520-527, June 15, 1999]

Section II: Targeting Therapuetics to the Liver

Targeting hepatocytes for drug and gene delivery: emerging novel approaches and applications
Jian Wu, Michael H. Nantz, Mark A. Zern

[Frontiers in Bioscience 7, d717-725, March 1, 2002]

Targeting hepatic stellate cells for cell-specific treatment of liver fibrosis
Leonie Beljaars, Dirk K.F. Meijer, Klaas Poelstra

[Frontiers in Bioscience 7, e214-222, May 1, 2002]

Targeting Kupffer cells with antisense oligonucleotides
Biddanda C. Ponnappa and Yedy Israel

[Frontiers in Bioscience 7, e223-233, May 1, 2002]