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VOLUME 11, ISSUE 1, JANUARY 1, 2006

Immunotherapy as part of a multidisciplinary approach to melanoma treatment
Adam I. Riker, Richard Jove, and Adil I. Daud

[Frontiers in Bioscience 11, 1-14, January 1, 2006]
[Abstract] [Full text] [PDF type I] 1775 [PDF Type II]
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A burning issue: do sepsis and systemic inflammatory response syndrome (SIRS) directly contribute to cardiac dysfunction?
Jun Ren and Shan Wu

[Frontiers in Bioscience 11, 15-22, January 1, 2006]
[Abstract] [Full text] [PDF type I] [PDF Type II]
[Order reprint Ms#:1776] [Help] [PubMed No] [DOI No: 10.2741/1776 ]

Sepsis-induced myocardial dysfunction and myocardial protection from ischemia/reperfusion injury
Kathleen H. McDonough, and Jitka Ismail Virag

[Frontiers in Bioscience 11, 23-32, January 1, 2006]
[Abstract] [Full text] [PDF type I] [PDF Type II]
[Order reprint Ms#:1777] [Help] [PubMed No] [DOI No: 10.2741/1777 ]

Neuroserpin
Giovanna Galliciotti and Peter Sonderegger

[Frontiers in Bioscience 11, 33-45, January 1, 2006]
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[Order reprint Ms#:1778] [Help] [PubMed No] [DOI No: 10.2741/1778 ]

Ii-Key/MHC class II epitope peptides as helper T cell vaccines for cancer and infectious disease
Nikoletta L. Kallinteris, Douglas Powell, Catherine E. Blackwell, MaryBeth Kim, Xueqing Lu, Shuzhen Wu, Robert E. Humphreys, Minzhen Xu, and Eric von Hofe

[Frontiers in Bioscience 11, 46-58, January 1, 2006]
[Abstract] [Full text] [PDF type I] [PDF Type II]
[Order reprint Ms#:1779] [Help] [PubMed No] [DOI No: 10.2741/1779 ]

Blood coagulation-dependent inflammation. Coagulation-dependent inflammation and inflammation-dependent thrombosis
Svetlana Strukova

[Frontiers in Bioscience 11, 59-80, January 1, 2006]
[Abstract] [Full text] [PDF type I] [PDF Type II]
[Order reprint Ms#:1780] [Help] [PubMed No] [DOI No: 10.2741/1780 ]

Changes in laminin isoforms associated with brain tumor invasion and angiogenesis
Julia Y. Ljubimova, Manabu Fujita, Natalya M. Khazenzon, Alexander V. Ljubimov and Keith L. Black

[Frontiers in Bioscience 11, 81-88, January 1, 2006]
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[Order reprint Ms#:1781] [Help] [PubMed No] [DOI No: 10.2741/1781 ]

HIV-1 inactivation by nucleic acid aptamers

Daniel M. Held, Jay D. Kissel, James T. Patterson , David G. Nickens and Donald H. Burke
[Frontiers in Bioscience 11, 89-112, January 1, 2006]
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[Order reprint Ms#:1782] [Help] [PubMed No] [DOI No: 10.2741/1782 ]

Inhibition of thrombin: relevance to anti-thrombosis strategy
Garry X. Shen

[Frontiers in Bioscience 11, 113-120, January 1, 2006]
[Abstract] [Full text] [PDF type I] [PDF Type II]
[Order reprint Ms#:1783] [Help] [PubMed No] [DOI No: 10.2741/1783 ]

Construction and direct immunization of eukaryotic expression plasmid encoding human soluble B lymphocyte stimulator
Guangyu Chen, Hongwu Du , Shanyun Peng, Donggang Xu, and Jiaxi Wang
[Frontiers in Bioscience 11, 121-125, January 1, 2006]
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[Order reprint Ms#:1784] [Help] [PubMed No] [DOI No: 10.2741/1784 ]

Stem cell factor (SCF)-Kit mediated phosphatidylinositol 3 (PI3) kinase signaling during mammalian oocyte growth and early follicular development
Kui Liu

[Frontiers in Bioscience 11, 126-135, January 1, 2006]
[Abstract] [Full text] [PDF type I] [PDF Type II]
[Order reprint Ms#:1785] [Help] [PubMed No] [DOI No: 10.2741/1785 ]

Phytate (Myo-inositol hexakisphosphate) inhibits cardiovascular calcifications in rats
Felix Grases, Pilar Sanchis, Joan Perello, Bernat Isern, Rafel Maria Prieto, Carlos Fernandez-Palomeque, Miguel Fiol, Oriol Bonnin and Jose Juan Torres

[Frontiers in Bioscience 11, 136-142, January 1, 2006]
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[Order reprint Ms#:1786] [Help] [PubMed No] [DOI No: 10.2741/1786 ]

Cloning and characterization of a novel spermiogenesis-related gene, T6441, in rat testis
Xin-Xin Song, Yin-Chuan Li, Yu-Qiang Shi, Xiao-Qian Hu, Zhao-Yuan Hu, Chun-Sheng Han and Yi-Xun Liu

[Frontiers in Bioscience 11, 143-150, January 1, 2006]
[Abstract] [Full text] [PDF type I] [PDF Type II]
[Order reprint Ms#:1787] [Help] [PubMed No] [DOI No: 10.2741/1787 ]

The concept of stem cell in the mammary gland and its implication in morphogenesis, cancer and prevention
Jose Russo, Gabriela A. Balogh, Jinqiang Chen, Sandra V. Fernandez, Rachael Fernbaugh, Rebecca Heulings, Daniel A. Mailo, Raquel Moral, Patricia A. Russo, Fathima Sheriff, Johana E. Vanegas, Richard Wang and Irma H. Russo

[Frontiers in Bioscience 11, 151-172, January 1, 2006]
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[Order reprint Ms#:1788] [Help] [PubMed No] [DOI No: 10.2741/1788 ]

Tissue transglutaminase: from biological glue to cell survival cues
Kapil Mehta, Jansina Y. Fok, and Lingegowda S. Mangala

[Frontiers in Bioscience 11, 173-185, January 1, 2006]
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[Order reprint Ms#:1789] [Help] [PubMed No] [DOI No: 10.2741/1789 ]

Novel probes for protein chip applications
Wei Liao, Su Guo, and Xin Sheng Zhao

[Frontiers in Bioscience 11, 186-197, January 1, 2006]
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[Order reprint Ms#:1790] [Help] [PubMed No] [DOI No: 10.2741/1790 ]

Chronic myeloid leukemia: why does it evolve from chronic phase to blast transformation?
Tariq I Mughal and John M Goldman

[Frontiers in Bioscience 11, 198-208, January 1, 2006]
[Abstract] [Full text] [PDF type I] 1791 [PDF Type II]
[Order reprint Ms#:1791] [Help] [PubMed No] [DOI No: 10.2741/1791 ]

Molecularly targeted treatment of chronic myeloid leukemia: beyond the imatinib era
Tariq I Mughal and John M Goldman

[Frontiers in Bioscience 11, 209-220, January 1, 2006]
[Abstract] [Full text] [PDF type I] [PDF Type II]
[Order reprint Ms#:1792] [Help] [PubMed No] [DOI No: 10.2741/1792 ]

Role of protein modifications mediated by transglutaminase 2 in human viral diseases
Ju-Hong Jeon and In-Gyu Kim

[Frontiers in Bioscience 11, 221-231, January 1, 2006]
[Abstract] [Full text] [PDF type I] [PDF Type II]
[Order reprint Ms#:1793] [Help] [PubMed No] [DOI No: 10.2741/1793 ]

Factor Xa inhibitors: new anti-thrombotic agents and their characteristics
Masahiro Ieko, Takashi Tarumi, Toru Nakabayashi, Mika Yoshida, Sumiyoshi Naito, and Takao Koike

[Frontiers in Bioscience 11, 232-248, January 1, 2006]
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[Order reprint Ms#:1794] [Help] [PubMed No] [DOI No: 10.2741/1794 ]

Molecular mechanisms responsible for the involvement of tissue transglutaminase in human diseases: celiac disease
Giuseppe Amantea, Marisa Cammarano, Lucia Zefferino, Antonio Martin, Gennaro Romito, Mariapina Piccirillo, and Vittorio Gentile

[Frontiers in Bioscience 11, 249-255, January 1, 2006]
[Abstract] [Full text] [PDF type I] [PDF Type II]
[Order reprint Ms#:1795] [Help] [PubMed No] [DOI No: 10.2741/1795 ]

Role of Tissue Factor in Thrombosis. Coagulation-Inflammation-Thrombosis circuit
Arthur J. Chu

[Frontiers in Bioscience 11, 256-271, January 1, 2006]
[Abstract] [Full text] [PDF type I] [PDF Type II]
[Order reprint Ms#:1796] [Help] [PubMed No] [DOI No: 10.2741/1796 ]

Contribution of anti-inflammatory/immune suppressive processes to the pathology of sepsis
Mario Perl, Chun-Shiang Chung, Megan Garber, Xin Huang, and Alfred Ayala

[Frontiers in Bioscience 11, 272-299, January 1, 2006]
[Abstract] [Full text] [PDF type I] [PDF Type II]
[Order reprint Ms#:1797] [Help] [PubMed No] [DOI No: 10.2741/1797 ]

Oxidative stress and apoptosis: a new treatment paradigm in cancer
Ryan H. Engel, and Andrew M. Evens

[Frontiers in Bioscience 11, 300-312, January 1, 2006]
[Abstract] [Full text] [PDF type I] [PDF Type II]
[Order reprint Ms#:1798] [Help] [PubMed No] [DOI No: 10.2741/1798 ]

Controlled gene activation and inactivation in the mouse
Moisés Mallo

[Frontiers in Bioscience 11, 313-327, January 1, 2006]
[Abstract] [Full text] [PDF type I] [PDF Type II]
[Order reprint Ms#:1799] [Help] [PubMed No] [DOI No: 10.2741/1799 ]

Blood clotting, inflammation, and thrombosis in cardiovascular events: perspectives
Christopher J. Boos and Gregory Y.H. Lip

[Frontiers in Bioscience 11, 328-336, January 1, 2006]
[Abstract] [Full text] [PDF type I] [PDF Type II]
[Order reprint Ms#:1800] [Help] [PubMed No] [DOI No: 10.2741/1800 ]

Tumor antigen targets and tumor immunotherapy
R. Allan Mufson

[Frontiers in Bioscience 11, 337-343, January 1, 2006]
[Abstract] [Full text] [PDF type I] [PDF Type II]
[Order reprint Ms#:1801] [Help] [PubMed No] [DOI No: 10.2741/1801 ]

Histone arginine methylation and its dynamic regulation
Joanna Wysocka, C. David Allis, and Scott Coonrod

[Frontiers in Bioscience 11, 344-355, January 1, 2006]
[Abstract] [Full text] [PDF type I] [PDF Type II]
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Regulation of vascular smooth muscle cell phenotype by cyclic GMP and cyclic GMP-dependent protein kinase
Thomas M. Lincoln, Xing Wu, Hassan Sellak, Nupur Dey and Chung-Sik Choi

[Frontiers in Bioscience 11, 356-367, January 1, 2006]
[Abstract] [Full text] [PDF type I] [PDF Type II]
[Order reprint Ms#:1803] [Help] [PubMed No] [DOI No: 10.2741/1803 ]

Beneficial autoimmunity participates in the regulation of rheumatoid arthritis
Yaniv Zohar, Gizi Wildbaum and Nathan Karin

[Frontiers in Bioscience 11, 368-379, January 1, 2006]
[Abstract] [Full text] [PDF type I] [PDF Type II]
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Co-evolutionary analysis of insulin/insulin like growth factor 1 signal pathway in vertebrate species
Tonghai Dou, Chaoneng Ji, Shaohua Gu, Jiaxi Xu, Jian Xu, Kang Ying, Yi Xie, and Yumin Mao

[Frontiers in Bioscience 11, 380-388, January 1, 2006]
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[Order reprint Ms#:1805] [Help] [PubMed No] [DOI No: 10.2741/1805 ]

Differential aromatase (CYP19) expression in human arteries from normal and neoplasic uterus : an immunohistochemical and in situ hybridization study
Calzada-Mendoza Claudia C, Sánchez C.Elena, Campos R.Rafael, Becerril M. Adriana, Madrigal B. Eduardo, Sierra R. Alfredo1, Mendez B. Enrique, Ocharán H. E., Herrera G. Norma1 and Ceballos-Reyes Guillermo

[Frontiers in Bioscience 11, 389-393, January 1, 2006]
[Abstract] [Full text] [PDF type I] [PDF Type II]
[Order reprint Ms#:1806] [Help] [PubMed No] [DOI No: 10.2741/1806 ]

Spectral and dose dependence of ultraviolet radiation-induced immunosuppression
Tai A. Phan, Gary M. Halliday, Ross StC. Barnetson and Diona L. Damian

[Frontiers in Bioscience 11, 394-411, January 1, 2006]
[Abstract] [Full text] [PDF type I] [PDF Type II]
[Order reprint Ms#:1807] [Help] [PubMed No] [DOI No: 10.2741/1807 ]

Effect of host age on tumor growth rate in rodents
Vladimir N. Anisimov

[Frontiers in Bioscience 11, 412-422, January 1, 2006]
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[Order reprint Ms#:1808] [Help] [PubMed No] [DOI No: 10.2741/1808 ]

Transcriptional regulation of matrix metalloprotease gene expression in health and disease
Arturo Mancini and John A. Di Battista

[Frontiers in Bioscience 11, 423-446, January 1, 2006]
[Abstract] [Full text] [PDF type I] [PDF Type II]
[Order reprint Ms#:1809] [Help] [PubMed No] [DOI No: 10.2741/1809 ]

MMPs - Role in Cardiovascular Development and Disease
Philip R. Brauer

[Frontiers in Bioscience 11, 447-478, January 1, 2006]
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[Order reprint Ms#:1810] [Help] [PubMed No] [DOI No: 10.2741/1810 ]

Matrix metalloproteinases: roles in cancer and metastasis
Barbara Fingleton

[Frontiers in Bioscience 11, 479-491, January 1, 2006]
[Abstract] [Full text] [PDF type I] [PDF Type II]
[Order reprint Ms#:1811] [Help] [PubMed No] [DOI No: 10.2741/1811 ]

Quantification of mycoplasmas in broth medium with sybr green-I and flow cytometry
Patrícia Assunção, Ruben S. Rosales, Maid Rifatbegovic, Nuno T. Antunes, Christian de la Fe, Carlos M. Ruiz de Galarreta and José B. Poveda

[Frontiers in Bioscience 11, 492-497, January 1, 2006]
[Abstract] [Full text] [PDF type I] [PDF Type II]
[Order reprint Ms#:1812] [Help] [PubMed No] [DOI No: 10.2741/1812 ]

Primary gastrointestinal stromal tumor of the liver with lung metastases successfully treated with STI-571 (imatinib mesylate)
Annarosaria De Chiara, Vincenzo De Rosa, Secondo Lastoria, Renato Franco, Gerardo Botti, Vincenzo Rosario Iaffaioli, and Gaetano Apice

[Frontiers in Bioscience 11, 498-501, January 1, 2006]
[Abstract] [Full text] [PDF type I] [PDF Type II]
[Order reprint Ms#:1813] [Help] [PubMed No] [DOI No: 10.2741/1813 ]

Phase I study of temozolomide and lomustine in the treatment of high grade malignant glioma
Salvatore Tafuto, Paolo Muto, Anna Tortoriello, Agata Pisano, Pasquale Comella, Roberta Formato, Stefano Quattrin and Rosario Vincenzo Iaffaioli

[Frontiers in Bioscience 11, 502-505, January 1, 2006]
[Abstract] [Full text] [PDF type I] [PDF Type II]
[Order reprint Ms#:1814] [Help] [PubMed No] [DOI No: 10.2741/1814 ]

Role of folate receptor genes in reproduction and related cancers
Hala Elnakat and Manohar Ratnam

[Frontiers in Bioscience 11, 506-519, January 1, 2006]
[Abstract] [Full text] [PDF type I] [PDF Type II]
[Order reprint Ms#:1815] [Help] [PubMed No] [DOI No: 10.2741/1815 ]

Role of the gut in the development of injury- and shock induced SIRS and MODS: the gut-lymph hypothesis, a review
Edwin A. Deitch, DaZhong, Xu, and Vicki L. Kaiser

[Frontiers in Bioscience 11, 520-528, January 1, 2006]
[Abstract] [Full text] [PDF type I] [PDF Type II]
[Order reprint Ms#:1816] [Help] [PubMed No] [DOI No: 10.2741/1816 ]

Matrix Metalloproteinases: Role In Arthritis
Peter S. Burrage, Kimberlee S. Mix and Constance E. Brinckerhoff

[Frontiers in Bioscience 11, 529-543, January 1, 2006]
[Abstract] [Full text] [PDF type I] [PDF Type II]
[Order reprint Ms#:1817] [Help] [PubMed No] [DOI No: 10.2741/1817 ]

MMPs and ADAMTSs: functional studies
Carl R. Flannery

[Frontiers in Bioscience 11, 544-569, January 1, 2006]
[Abstract] [Full text] [PDF type I] [PDF Type II]
[Order reprint Ms#:1818] [Help] [PubMed No] [DOI No: 10.2741/1818 ]

Genetic basis for necrotizing enterocolitis - risk factors and their relations to genetic polymorphisms
Andras Treszl, Tivadar Tulassay, and Barna Vasarhelyi

[Frontiers in Bioscience 11, 570-580, January 1, 2006]
[Abstract] [Full text] [PDF type I] [PDF Type II]
[Order reprint Ms#:1819] [Help] [PubMed No] [DOI No: 10.2741/1819 ]

Selective conservation of the RSL-encoding, proteinase inhibitory-type, clade L serpins in Caenorhabditis species
Cliff J. Luke, Stephen C. Pak, David J. Askew, Yuko S. Askew, Justin E. Smith and Gary A. Silverman

[Frontiers in Bioscience 11, 581-594, January 1, 2006]
[Abstract] [Full text] [PDF type I] [PDF Type II]
[Order reprint Ms#:1820] [Help] [PubMed No] [DOI No: 10.2741/1820 ]

Endometriosis: harmful survival of an ectopic tissue
Janos Garai, Valeria Molnar, Tamas Varga, Miklos Koppan, Attila Torok, and Jozsef Bodis

[Frontiers in Bioscience 11, 595-619, January 1, 2006]
[Abstract] [Full text] [PDF type I] [PDF Type II]
[Order reprint Ms#:1821] [Help] [PubMed No] [DOI No: 10.2741/1821 ]

Meiotic spindle, spindle checkpoint and embryonic aneuploidy
Wei-Hua Wang and Qing-Yuan Sun

[Frontiers in Bioscience 11, 620-636, January 1, 2006]
[Abstract] [Full text] [PDF type I] [PDF Type II]
[Order reprint Ms#:1822] [Help] [PubMed No] [DOI No: 10.2741/1822 ]

Involvement of SMAD4, but not of SMAD2, in transforming growth factor-beta1-induced trophoblast expression of matrix metalloproteinase-2
Hai-Yan Lin, Qing Yang, Hong-Mei Wang, Jian-Guo Qi, Heng Zhang, Hong-Xing Wang, Benjamin K. Tsang, and Cheng Zhu

[Frontiers in Bioscience 11, 637-646, January 1, 2006]
[Abstract] [Full text] [PDF type I] [PDF Type II]
[Order reprint Ms#:1823] [Help] [PubMed No] [DOI No: 10.2741/1823 ]

The KISS1 metastasis suppressor: mechanistic insights and clinical utility
Kevin T. Nash and Danny R. Welch

[Frontiers in Bioscience 11, 647-659, January 1, 2006]
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[Order reprint Ms#:1824] [Help] [PubMed No] [DOI No: 10.2741/1824 ]

A comparison of regional and systemic humoral immune responses to a nematode infection
Ching-Hua Wang, Stephen Douglas Wagner, Humberto Montalvo Jr., Christopher Lars Hauschild, and Amanda Michell Vanhoose

[Frontiers in Bioscience 11, 660-668, January 1, 2006]
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[Order reprint Ms#:1825] [Help] [PubMed No] [DOI No: 10.2741/1825 ]

Molecular Pathogenesis of Hepatolithiasis - A Type of Low Phospholipid-Associated Cholelithiasis
Junichi Shoda , Yoichi Inada, and Toshiaki Osuga

[Frontiers in Bioscience 11, 669-675, January 1, 2006]
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[Order reprint Ms#:1826] [Help] [PubMed No] [DOI No: 10.2741/1826 ]

Activated protein C and sepsis
Lee A O'Brien, Akanksha Gupta and Brian W. Grinnell

[Frontiers in Bioscience 11, 676-698, January 1, 2006]
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[Order reprint Ms#:1827] [Help] [PubMed No] [DOI No: 10.2741/1827 ]

The application of HSP70 as a target for gene therapy
Zhen Zheng and Midori A. Yenari

[Frontiers in Bioscience 11, 699-707, January 1, 2006]
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[Order reprint Ms#:1828] [Help] [PubMed No] [DOI No: 10.2741/1828 ]

The multiple functions of HIV-1 Tat: proliferation versus apoptosis
Francesca Peruzzi

[Frontiers in Bioscience 11, 708-717, January 1, 2006]
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[Order reprint Ms#:1829] [Help] [PubMed No] [DOI No: 10.2741/1829 ]

HIV disorders of the brain; pathology and pathogenesis
Luis Del Valle and Sergio Piña-Oviedo

[Frontiers in Bioscience 11, 718-732, January 1, 2006]
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The WNT/Beta-catenin pathway in melanoma
Lionel Larue and Véronique Delmas

[Frontiers in Bioscience 11, 733-742, January 1, 2006]
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[Order reprint Ms#:1831] [Help] [PubMed No] [DOI No: 10.2741/1831 ]

New animal models to study the role of tyrosinase in normal retinal development
Alfonso Lavado, and Lluis Montoliu

[Frontiers in Bioscience 11, 743-752, January 1, 2006]
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[Order reprint Ms#:1832] [Help] [PubMed No] [DOI No: 10.2741/1832 ]

HVJ-based non-viral gene transfer method: successful gene therapy using HGF and VEGF genes in experimental ischemia
Munehisa Shimamura, Naoyuki Sato, Shinichi Yoshimura, Yasufumi Kaneda, and Ryuichi Morishita

[Frontiers in Bioscience 11, 753-759, January 1, 2006]
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[Order reprint Ms#:1833] [Help] [PubMed No] [DOI No: 10.2741/1833 ]

Ex vivo gene therapy: transplantation of neurotrophic factor-secreting cells for cerebral ischemia
Takao Yasuhara, Cesario V. Borlongan, and Isao Date

[Frontiers in Bioscience 11, 760-775, January 1, 2006]
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[Order reprint Ms#:1834] [Help] [PubMed No] [DOI No: 10.2741/1834 ]

Human periodontal ligament cells express osteoblastic phenotypes under intermittent force loading in vitro
Y. Q. Yang, X. T. Li, A. B. M. Rabie, M. K. Fu and D. Zhang

[Frontiers in Bioscience 11, 776-781, January 1, 2006]
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[Order reprint Ms#:1835] [Help] [PubMed No] [DOI No: 10.2741/1835 ]

Second-line intra-arterial chemotherapy in advanced pancreatic adenocarcinoma
Emiddio Barletta, Francesco Fiore, Bruno Daniele, Alessandro Ottaiano, Roberto D'Angelo, Ettore Ferrari, Roberta Formato, Anna Tortoriello, Giacinto Turitto, Giovanni Salvatore Bruni, Sandro Pignata, and Rosario Vincenzo Iaffaioli

[Frontiers in Bioscience 11, 782-787, January 1, 2006]
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Costimulatory Molecules as Adjuvants for Immunotherapy
James W. Hodge, John W. Greiner, Kwong-Yok Tsang, Helen Sabzevari, Chie Kudo-Saito, Douglas W. Grosenbach, James L. Gulley, Philip M. Arlen, John L. Marshall, Dennis Panicali, and Jeffrey Schlom

[Frontiers in Bioscience 11, 788-803, January 1, 2006]
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[Order reprint Ms#:1837] [Help] [PubMed No] [DOI No: 10.2741/1837 ]

Viral Vectors for Cancer Immunotherapy
Richard Harrop and Miles W. Carroll

[Frontiers in Bioscience 11, 804-817, January 1, 2006]
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[Order reprint Ms#:1838] [Help] [PubMed No] [DOI No: 10.2741/1838 ]

VEGFR-1 and VEGFR-2: two non-identical twins with a unique physiognomy
Nader Rahimi

[Frontiers in Bioscience 11, 818-829 January 1, 2006]
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[Order reprint Ms#:1839] [Help] [PubMed No] [DOI No: 10.2741/1839 ]

Platelet-leukocyte aggregates and derived microparticles in inflammation, vascular remodelling and thrombosis
Lilian McGregor, Juliette Martin, and John L. McGregor

[Frontiers in Bioscience 11, 830-837, January 1, 2006]
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[Order reprint Ms#:1840] [Help] [PubMed No] [DOI No: 10.2741/1840 ]

Setting the stage for bench-to-bedside movement of anti-HIV RNA inhibitors-gene therapy for AIDS in macaques
Stephen E. Braun, and R. Paul Johnson

[Frontiers in Bioscience 11, 838-851, January 1, 2006]
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[Order reprint Ms#:1841] [Help] [PubMed No] [DOI No: 10.2741/1841 ]

Mechanisms of X-chromosome inactivation
Samuel C. Chang, Tracy Tucker, Nancy P. Thorogood, and Carolyn J. Brown

[Frontiers in Bioscience 11, 852-866, January 1, 2006]
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[Order reprint Ms#:1842] [Help] [PubMed No] [DOI No: 10.2741/1842 ]

Tissue transglutaminase (TG2) - a wound response enzyme
Dilek Telci, and Martin Griffin

[Frontiers in Bioscience 11, 867-882, January 1, 2006]
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[Order reprint Ms#:1843] [Help] [PubMed No] [DOI No: 10.2741/1843 ]

Tet responsive and adenovirus based constructs for regulated in vivo expression of Lefty
Anatoly Mikhailik, Meiyi Tang, Patrick Hearing, Viswanathan Ravishankar and Siamak Tabibzadeh

[Frontiers in Bioscience 11, 883-888, January 1, 2006]
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Levels of IL-1 beta control stimulatory/inhibitory growth of cancer cells
Deodutta Roy, Shubhashish Sarkar, and Quentin Felty

[Frontiers in Bioscience 11, 889-898, January 1, 2006]
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[Order reprint Ms#:1845] [Help] [PubMed No] [DOI No: 10.2741/1845 ]

Homing genes, cell therapy and stroke
Woei-Cherng Shyu, Yih-Jing Lee, Demeral David Liu, Shinn-Zong Lin and Hung Li

[Frontiers in Bioscience 11, 899-907, January 1, 2006]
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[Order reprint Ms#:1846] [Help] [PubMed No] [DOI No: 10.2741/1846 ]

Pathogenesis and genetic basis for retinopathy of prematurity
Krisztina Csak, Viktoria Szabo, Andras Szabo, Adam Vannay

[Frontiers in Bioscience 11, 908-920, January 1, 2006]
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[Order reprint Ms#:1847] [Help] [PubMed No] [DOI No: 10.2741/1847 ]

Signal transduction in CD4+CD25+ regulatory T cells: CD25 and IL-2
Angela M. Thornton

[Frontiers in Bioscience 11, 921-927, January 1, 2006]
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[Order reprint Ms#:1848] [Help] [PubMed No] [DOI No: 10.2741/1848 ]

Advances in malignant melanoma: genetic insights from mouse and man
Omar Kabbarah and Lynda Chin

[Frontiers in Bioscience 11, 928-942, January 1, 2006]
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[Order reprint Ms#:1849] [Help] [PubMed No] [DOI No: 10.2741/1849 ]

Repeated Mechanical Loading Enhances the Expression of Indian Hedgehog in Condylar Cartilage
Ng T.C.S, Chiu K. W. K., Rabie A.B.M., U. Hägg

[Frontiers in Bioscience 11, 943-948, January 1, 2006]
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[Order reprint Ms#:1850] [Help] [PubMed No] [DOI No: 10.2741/1850 ]

Factors regulating condylar cartilage growth under repeated load application
A. F. S. Ng, Y. Q. Yang, R. W. K. Wong, E. U. O. Hägg, and A. B. M. Rabie

[Frontiers in Bioscience 11, 949-954, January 1, 2006]
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[Order reprint Ms#:1851] [Help] [PubMed No] [DOI No: 10.2741/1851 ]

Understanding the role of dietary components on atherosclerosis using genetic engineered mouse models
Alfonso J. Sarria, Joaquin C. Surra, Sergio Acin, Ricardo Carnicer, Maria A. Navarro, Jose M. Arbones-Mainar, Natalia Guillen, Maria V. Martinez-Gracia, Carmen Arnal and Jesus Osada

[Frontiers in Bioscience 11, 955-967, January 1, 2006]
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[Order reprint Ms#:1852] [Help] [PubMed No] [DOI No: 10.2741/1852 ]

Chronically increased intrarenal angiotensin II causes nephropathy in an animal model of type 2 diabetes
Ram Sharma, Mukut Sharma, Sreenivas Reddy, Virginia J. Savin, Abdul Mateen Nagaria, and Thomas B. Wiegmann

[Frontiers in Bioscience 11, 968-976, January 1, 2006]
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[Order reprint Ms#:1853] [Help] [PubMed No] [DOI No: 10.2741/1853 ]

Genes differentially expressed in responsive and refractory acute leukemia
Qing Wei, Yao Li, Li Chen, Liying Zhang, Xianmin He, Xuping Fu, Kang Ying, Jianfeng Huang, Qin Chen, Yi Xie, and Yumin Mao

[Frontiers in Bioscience 11, 977-982, January 1, 2006]
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[Order reprint Ms#:1854] [Help] [PubMed No] [DOI No: 10.2741/1854 ]

An impedance biosensor array for label-free detection of multiple antigen-antibody reactions
Xiaobo Yu, Dawei Xu, Danke Xu, Renjie Lv, and Zhihong Liu

[Frontiers in Bioscience 11, 983-990, January 1, 2006]
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[Order reprint Ms#:1855] [Help] [PubMed No] [DOI No: 10.2741/1855 ]

Studies on formation and repair of formaldehyde-damaged DNA by detection of DNA-protein crosslinks and DNA breaks
Yingshuai Liu, Chang M Li, Zhisong Lu, Shumao Ding, Xu Yang, and Jianwei Mo

[Frontiers in Bioscience 11, 991-997, January 1, 2006]
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[Order reprint Ms#:1856] [Help] [PubMed No] [DOI No: 10.2741/1856 ]

Alcohol intoxication and post-burn complications
Mashkoor A. Choudhry and Irshad H. Chaudry

[Frontiers in Bioscience 11, 998-1005, January 1, 2006]
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[Order reprint Ms#:1857] [Help] [PubMed No] [DOI No: 10.2741/1857 ]

Hypothermia and Sepsis
Daniel G. Remick and Hongyan Xioa

[Frontiers in Bioscience 11, 1006-1013, January 1, 2006]
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[Order reprint Ms#:1858] [Help] [PubMed No] [DOI No: 10.2741/1858 ]

TGF-beta and CD4+CD25+ Regulatory T cells
Samuel Huber, and Christoph Schramm

[Frontiers in Bioscience 11, 1014-1023, January 1, 2006]
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[Order reprint Ms#:1859] [Help] [PubMed No] [DOI No: 10.2741/1859 ]

Chemokines in Tumor Immunotherapy
Kenneth Flanagan and Howard L. Kaufman

[Frontiers in Bioscience 11, 1024-1030, January 1, 2006]
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[Order reprint Ms#:1860] [Help] [PubMed No] [DOI No: 10.2741/1860 ]

Epidermal stem cells
Angela Webb and Pritinder Kaur

[Frontiers in Bioscience 11, 1031-1041, January 1, 2006]
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[Order reprint Ms#:1861] [Help] [PubMed No] [DOI No: 10.2741/1861 ]

Serpins, the vasculature, and viral therapeutics
Jakob Richardson, Kasinath Viswanathan and Alexandra Lucas

[Frontiers in Bioscience 11, 1042-1056, January 1, 2006]
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[Order reprint Ms#:1862] [Help] [PubMed No] [DOI No: 10.2741/1862 ]

The role of tissue transglutaminase in cell-matrix interactions
Evgeny A. Zemskov, Anna Janiak, Jun Hang, Anu Waghray and Alexey M. Belkin

[Frontiers in Bioscience 11, 1057-1076, January 1, 2006]
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[Order reprint Ms#:1863] [Help] [PubMed No] [DOI No: 10.2741/1863 ]

Germ cell apoptosis induced by experimental cryptorchidism is mediated by multiple molecular pathways in Cynomolgus Macaque
S-X Tao, J Guo, X-S Zhang, Y-C Li, Z-Y Hu, C-S Han and Y-X Liu

[Frontiers in Bioscience 11, 1077-1089, January 1, 2006]
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[Order reprint Ms#:1864] [Help] [PubMed No] [DOI No: 10.2741/1864 ]

Gene therapy, cell transplantation and stroke
Cesario V. Borlongan, Christina Fournier, Christine E. Stahl, Guolong Yu, Lin Xu, Noriyuki Matsukawa, Mary Newman, Takao Yasuhara, Koichi Hara, David C. Hess, and Paul R. Sanberg

[Frontiers in Bioscience 11, 1090-1100, January 1, 2006]
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[Order reprint Ms#:1865] [Help] [PubMed No] [DOI No: 10.2741/1865 ]

Viral vector strategy for glial cell line-derived neurotrophic factor therapy for stroke
Yun Wang, Omar B. Alexander, Yee-Ming Woodward-Pu, Christine E. Stahl, and Cesario V.Borlongan

[Frontiers in Bioscience 11, 1101-1107, January 1, 2006]
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[Order reprint Ms#:1866] [Help] [PubMed No] [DOI No: 10.2741/1866 ]

Mammalian genome targeting using site-specific recombinases
Angel-Luis García-Otín and Florian Guillou

[Frontiers in Bioscience 11, 1108-1136, January 1, 2006]
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[Order reprint Ms#:1867] [Help] [PubMed No] [DOI No: 10.2741/1867 ]

Role of NuMA in vertebrate cells: review of an intriguing multifunctional protein
Qing-Yuan Sun and Heide Schatten

[Frontiers in Bioscience 11, 1137-1146, January 1, 2006]
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[Order reprint Ms#:1868] [Help] [PubMed No] [DOI No: 10.2741/1868 ]

A Redox Active and Electrochemiluminescent Threading Bis-Intercalator and its Applications in DNA Assays
Hong Xie, Natalia C.Tansil and Zhiqiang Gao

[Frontiers in Bioscience 11, 1147-1157, January 1, 2006]
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[Order reprint Ms#:1869] [Help] [PubMed No] [DOI No: 10.2741/1869 ]

Comparative analysis of cell phenotypes in different severe clinical forms of Chagas' disease
Glenda M. Cardoso, Morato M. J.F., Gomes J.A S. , Rocha M.O.C., Bonfim I.P., Williams-Blangero S., VandeBerg J.L., Reis M.R., Magalhães E.F.L and Correa-Oliveira R

[Frontiers in Bioscience 11, 1158-1163, January 1, 2006]
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[Order reprint Ms#:1870] [Help] [PubMed No] [DOI No: 10.2741/1870 ]

Cyclins and CDKS in development and cancer: lessons from genetically modified mice
David Santamaria and Sagrario Ortega

[Frontiers in Bioscience 11, 1164-1188, January 1, 2006]
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[Order reprint Ms#:1871] [Help] [PubMed No] [DOI No: 10.2741/1871 ]

DNA vaccines for cancer
Denise R. Shaw and Theresa V. Strong

[Frontiers in Bioscience 11, 1189-1198, January 1, 2006]
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[Order reprint Ms#:1872] [Help] [PubMed No] [DOI No: 10.2741/1872 ]

VOLUME 11, ISSUE 1, MAY 1, 2006

Regulation of matrix metalloproteinase (MMP) gene expression by protein kinases
Paul M. Reuben and Herman S. Cheung

[Frontiers in Bioscience 11, 1199-1215, May 1, 2006]
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[Order reprint Ms#:1873] [Help] [PubMed No] [DOI No: 10.2741/1873 ]

Using Inbred Mouse Strains to Identify Genes for Complex Diseases
Hooman Allayee, Ali Andalibi, and Margarete Mehrabian

[Frontiers in Bioscience 11, 1216-1226, May 1, 2006]
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[Order reprint Ms#:1874] [Help] [PubMed No] [DOI No: 10.2741/1874 ]

The clinical significance of sperm-zona pellucida binding: 17 years later
Daniel R Franken, and Sergio Oehninger

[Frontiers in Bioscience 11, 1227-1233, May 1, 2006]
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[Order reprint Ms#:1875] [Help] [PubMed No] [DOI No: 10.2741/1875 ]

Tolerance to autoimmune thyroiditis: CD4+CD25+ regulatory T cells influence susceptibility but do not supersede MHC class II restriction
Gerald P. Morris and Yi-chi M. Kong

[Frontiers in Bioscience 11, 1234-1243, May 1, 2006]
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[Order reprint Ms#:1876] [Help] [PubMed No] [DOI No: 10.2741/1876 ]

The Current Epidemiology of Cutaneous Malignant Melanoma
Marianne Berwick and Charles Wiggins

[Frontiers in Bioscience 11, 1244-1254, May 1, 2006]
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[Order reprint Ms#:1877] [Help] [PubMed No] [DOI No: 10.2741/1877 ]

Distinction of brain tissue, low grade and high grade glioma with time-resolved fluorescence spectroscopy
William H. Yong, Pramod V. Butte, Brian K. Pikul, Javier A. Jo, Qiyin Fang, Thanassis Papaioannou, Keith L. Black, and Laura Marcu

[Frontiers in Bioscience 11, 1255-1263, May 1, 2006]
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[Order reprint Ms#:1878] [Help] [PubMed No] [DOI No: 10.2741/1878 ]

Phosphoinositides in FCgamma receptor signaling
James W. Booth

[Frontiers in Bioscience 11, 1264-1274, May 1, 2006]
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[Order reprint Ms#:1879] [Help] [PubMed No] [DOI No: 10.2741/1879 ]

Phase II study of neoadjuvant concurrent chemioradiotherapy with oxaliplatin-containig regimen in locally advanced rectal cancer
Giacinto Turitto, Giancarlo Panelli, Adele Frattolillo, Annunziata Auriemma, Ferdinando Salzano de Luna, Giampiero Cione, Carlo Paolo De Angelis, Paolo Muto, and Rosario Vincenzo Iaffaioli

[Frontiers in Bioscience 11, 1275-1279, May 1, 2006]
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[Order reprint Ms#:1880] [Help] [PubMed No] [DOI No: 10.2741/1880 ]

Surgery, radiotherapy and temozolomide in treating high-grade gliomas
Ciro Parlato, Manlio Barbarisi, Marco Moraci, and Aldo Moraci

[Frontiers in Bioscience 11, 1280-1283, May 1, 2006]
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[Order reprint Ms#:1881] [Help] [PubMed No] [DOI No: 10.2741/1881 ]

Stop Flow in abdominal and pelvic cancer relapses
Rosario Vincenzo Iaffaioli, Gaetano Facchini, Anna Tortoriello, Feliciano Crovella, Giovannni Romano, Roberta Formato, Michele Santangelo, Emiddio Barletta, Francesco Fiore, Vittorio Iaccarino, Bruno Memoli, Roberto D'Angelo, Pier Luigi Pilati, Riccardo Rossi, Stefano Guadagni, Marcello Deraco, Sandro Pignata, Bruno Daniele, Gerardo Rosati, Bruno Massidda, Giovanni Mantovani, Enrico Di Salvo, Nicola Marzano, Vincenzo Memeo, Valerio Parisi, Giorgio Mallarini, and Giuseppe Colucci

[Frontiers in Bioscience 11, 1284-1288, May 1, 2006]
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[Order reprint Ms#:1882] [Help] [PubMed No] [DOI No: 10.2741/1882 ]

Matrix metalloproteinases and diseases of the central nervous system with a special emphasis on ischemic brain
Yvan Gasche, Paola Marina Soccal, Michiko Kanemitsu, and Jean-Christophe Copin

[Frontiers in Bioscience 11, 1289-1301, May 1, 2006]
[Abstract] [Full text] [PDF type I] [PDF Type II]
[Order reprint Ms#:1883] [Help] [PubMed No] [DOI No: 10.2741/1883 ]

Identification and differentiation of hepatic stem cells during liver development
Akihide Kamiya, Frank J. Gonzalez, and Hiromitsu Nakauchi

[Frontiers in Bioscience 11, 1302-1310, May 1, 2006]
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[Order reprint Ms#:1884] [Help] [PubMed No] [DOI No: 10.2741/1884 ]

LS-CAP: an algorithm for identifying cytogenetic aberrations in hepatocellular carcinoma using microarray data
Xianmin He, Qing Wei, Meiqian Sun, Xuping Fu, Sichang Fan, and Yao Li

[Frontiers in Bioscience 11, 1311-1322, May 1, 2006]
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[Order reprint Ms#:1885] [Help] [PubMed No] [DOI No: 10.2741/1885 ]

Experimental therapy with tissue kallikrein against cerebral ischemia
Julie Chao, and Lee Chao

[Frontiers in Bioscience 11, 1323-1327, May 1, 2006]
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[Order reprint Ms#:1886] [Help] [PubMed No] [DOI No: 10.2741/886 ]

Antiatherogenic role of high-density lipoproteins: insights from genetically engineered-mice
Joan Carles Escola-Gil Laura Calpe-Berdiel, Xavier Palome, Vicent Ribas, Jordi Ordonez-Llanos and Francisco Blanco-Vaca

[Frontiers in Bioscience 11, 1328-1348, May 1, 2006]
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[Order reprint Ms#:1887] [Help] [PubMed No] [DOI No: 10.2741/1887 ]

Tissue Factor Initiated Blood Coagulation
Keith Gomez and John H. McVey

[Frontiers in Bioscience 11, 1349-1359, May 1, 2006]
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[Order reprint Ms#:1888] [Help] [PubMed No] [DOI No: 10.2741/1888 ]

Dendritic Cells and CD4+CD25+ T Regulatory Cells: Crosstalk Between Two Professionals in Immunity versus Tolerance
WanJun Chen

[Frontiers in Bioscience 11, 1360-1370, May 1, 2006]
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[Order reprint Ms#:1889] [Help] [PubMed No] [DOI No: 10.2741/1889 ]

Genetics of perinatal brain injury in the preterm infant
Ronald John Baier

[Frontiers in Bioscience 11, 1371-1387, May 1, 2006]
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[Order reprint Ms#:1890] [Help] [PubMed No] [DOI No: 10.2741/1890 ]

Prostate cancer epidemiology
Ann W. Hsing and Anand P. Chokkalingam

[Frontiers in Bioscience 11, 1388-1413, May 1, 2006]
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[Order reprint Ms#:1891] [Help] [PubMed No] [DOI No: 10.2741/1891 ]

Microarray tools for deciphering complex diseases
Ruty Mehrian Shai

[Frontiers in Bioscience 11, 1414-1424, May 1, 2006]
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[Order reprint Ms#:1892] [Help] [PubMed No] [DOI No: 10.2741/1892 ]

Different fates of donor mitochondrial DNA in bovine-rabbit and cloned bovine-rabbit reconstructed embryos during preimplantation development
Yan Jiang, Tao Chen, Kai Wang, Man-Xi Jiang, Shu-Zhen Liu, Ying-Chun Ouyang, Qing-Yuan Sunand Da-Yuan Chen

[Frontiers in Bioscience 11, 1425-1432, May 1, 2006]
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[Order reprint Ms#:1893] [Help] [PubMed No] [DOI No: 10.2741/1893 ]

Pathophysiology of sperm motility
Michaela Luconi, Gianni Forti, and Elisabetta Baldi

[Frontiers in Bioscience 11, 1433-1447, May 1, 2006]
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[Order reprint Ms#:1894] [Help] [PubMed No] [DOI No: 10.2741/1894 ]

Signaling triggered by glucocorticoid-induced tumor necrosis factor receptor family-related gene: Regulation at the interface between regulatory T cells and immune effector cells
Edward M. Esparza and Robert H. Arch

[Frontiers in Bioscience 11, 1448-1465, May 1, 2006]
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[Order reprint Ms#:1895] [Help] [PubMed No] [DOI No: 10.2741/1895 ]

Improving the delivery of therapeutic agents to CNS neoplasms: a clinical review
Michael A. Badruddoja, and Keith L. Black

[Frontiers in Bioscience 11, 1466-1478, May 1, 2006]
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[Order reprint Ms#:1896] [Help] [PubMed No] [DOI No: 10.2741/1896 ]

Role of microtubules and myosins in Fc gamma receptor-mediated phagocytosis
Nobukazu Araki

[Frontiers in Bioscience 11, 1479-1490, May 1, 2006]
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[Order reprint Ms#:1897] [Help] [PubMed No] [DOI No: 10.2741/1897 ]

Origin and biological significance of DNA fragmentation in human spermatozoa
Monica Muratori, Sara Marchiani, Mario Maggi, Gianni Forti and Elisabetta Baldi

[Frontiers in Bioscience 11, 1491-1499, May 1, 2006]
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[Order reprint Ms#:1898] [Help] [PubMed No] [DOI No: 10.2741/1898 ]

Cloning, characterization and subcellular localization of a gene encoding a human ubiquitin-conjugating enzyme (E2) homologous to the Arabidopsis thaliana UBC-16 gene product
Gang Yin, Chaoneng Ji, Tong Wu, Zhouliang Shen, Xin Xu, Yi Xie, and Yumin Mao

[Frontiers in Bioscience 11, 1500-1507, May 1, 2006]
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[Order reprint Ms#:1899] [Help] [PubMed No] [DOI No: 10.2741/1899 ]

Posttranslational modifications of Bcl2 family members-a potential therapeutic target for human malignancy
Aruna Basu, Garrett DuBois and Subrata Haldar

[Frontiers in Bioscience 11, 1508-1521, May 1, 2006]
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[Order rep