NAME: Curtis A. Machida, Ph. D. DEPT: Department of Integrative Biosciences
ORGANIZATION: Oregon Health & Science University
ADDRESS: 611 SW Campus Drive
TELEPHONE No: 503-494-0034
FAX No: 503-494-8554
E MAIL ADDRESS: machidac@ohsu.edu
TITLE: Research Associate Professor
TOTAL GRANTS: 3
TOTAL PUBLICATIONS: 48
MEMBERSHIPS ON EDITORIAL BOARDS: Frontiers in Bioscience, Molecular Biotechnology

SUBJECT(S) OF RESEARCH: adrenergic receptors and posttranscriptional control; mechanisms of mRNA stability; use of retroviral vectors for gene transfer and gene therapy
DISCIPLINE(S): Biochemistry, Molecular Biology, and Cell Biology
ORGAN SYSTEMS: nervous system; cardiovascular system
TISSUES: cortical regions; heart
CELL(S): established cell lines derived from the nervous system and the heart
MOLECULE(S): adrenergic receptor mRNA; 3' UTR binding proteins; RNA stability, degradation, and nuclear export factors
TECHNIQUE(S): recombinant DNA techniques; RNase protection assays; UV-crosslinking / immunoprecipitation assays; yeast hybrid genetic systems