NAME: Simon Scott
DEPT: Academic Unit of Pathology, Division of Genomic Medicine
ORGANIZATION: University of Sheffield
ADDRESS: Academic Unit of Patology, Division of Genomic Medicine, University of Sheffield Medical School, Sheffield S10 2RX, UK
TELEPHONE No: ++44 114 2712733
FAX No: ++44 114 2261464
E MAIL ADDRESS: s.d.scott@sheffield.ac.uk
TITLE: Dr
TOTAL GRANTS: 2
TOTAL PUBLICATIONS: 22
MEMBERSHIPS ON EDITORIAL BOARDS: Frontiers in Bioscience

SUBJECT(S) OF RESEARCH: Tumor-targeted gene therapy; radiation and hypoxia activated therapeutic vectors; viral and cellular delivery. tumor microcirculation
DISCIPLINE(S): Cancer research; molecular biology, virology, radiobiology
ORGAN SYSTEMS: N/A
TISSUES: Brain, breast, prostate, etc.
CELL(S): Monocytes, macrophages, established tumor and mononuclear cell lines
MOLECULE(S): Hypoxia-inducible factor (HIF); Early growth response (EGR); herpes simplex virus thymidine kinase (HSV tk); ganciclovir (GCV);
TECHNIQUE(S): DNA vector construction and cloning, biochemical assays; viral and non-viral gene transfer; tumor implantation and treatment; external beam irradiation