Zheng, 1996

Mice deficient for the amyloid precursor protein gene.
Ann. N. Y. Acad. Sci. 777, 421-426 (1996) [96187055]
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( (app))

	Line Name	DNA Construct
1.	APP (+/-)	The APP promoter region was isolated from a 129 mouse library by using a 1.0 kb HindIII-Pvull fragment from the APP promoter as a probe (G00-604-577). The ta....
2.	APP (-/-)	The APP promoter region was isolated from a 129 mouse library by using a 1.0 kb HindIII-Pvull fragment from the APP promoter as a probe (G00-604-577). The ta....
3.	V717F beta-amyloidP	A platelet-derived growth factor (PDGF)-beta promoter was used to drive a human beta-amyloid precursor protein (hAPP) minigene encoding the APP(717V-->F) mutation associ....
4.	NF(L)/A-beta J4	The sequence encoding the Ab peptide was generated by RT-PCR using rat brain RNA, because it will yield a peptide identical to the mouse. The forward primer contained a....
5.	NF(L)/ A-beta G2	The sequence encoding the Ab peptide was generated by RT-PCR using rat brain RNA, because it will yield a peptide identical to the mouse. The forward primer contained a....
6.	NF(L)A-beta J3	The sequence encoding the Ab peptide was generated by RT-PCR using rat brain RNA, because it will yield a peptide identical to the mouse. The forward primer contained a....