B7

Lack of B7 expression
70% decrease in costimulation of response to alloantigen

Freeman et al., 1993

((b7))

	Line Name	DNA Construct
1.	B7 (+/-)	A targeting vector that allowed positive and negative selection was generated by insertion of the neo gene driven by the mouse phosphoglycerol kinase (PGK) promoter into....
2.	B7 (-/-)	A targeting vector that allowed positive and negative selection was generated by insertion of the neo gene driven by the mouse phosphoglycerol kinase (PGK) promoter into....