c-mos

 Fertile males
 Reduced fertility in females due to failure of mature eggs to arrest during meiosis
 Parthenogenetic development of unfertilized eggs

Colledge et al., 1994


METHODOLOGY ( FROM T-BASE)

((c-mos))

Line Name DNA Construct
1. c-mos (+/-) Plasmid pNMV was constructing by inserting a neomycin-resistance gene (neo(r)) with a pgk-1 promoter in the same orientation as the c-mos gene into the BlnI (....
2. c-mos (+/-) To generate the targeting plamid, a 2.8-kb SacI-HindIII c-mos genomic fragment from pMS-1 was cloned into the corresponding sites of pSP64 to give....
3. c-mos (-/-) Plasmid pNMV was constructing by inserting a neomycin-resistance gene (neo(r)) with a pgk-1 promoter in the same orientation as the c-mos gene into the BlnI (....
4. c-mos (-/-) To generate the targeting plamid, a 2.8-kb SacI-HindIII c-mos genomic fragment from pMS-1 was cloned into the corresponding sites of pSP64 to give....


Database links

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