c-myc

Retarded growth
Reduced fertility of the heterozygotes due to embryonic resorption prior to day 9.5 of gestation
Death 9.5-10.5 days after gestation

Davis et al., 1993

((c-myc))

	Line Name	DNA Construct
1.	TG.M or 141-3	MMTV/c-myc; c-myc oncogene driven by mouse mammary tumor virus promoter/enhancer
2.	HTLV-I LTR/c-myc (T	The HTLV-I/c-myc construct contains the entire U3 and R regions and 105 bp of the U5 region from the HTLV-I 3' LTR placed 5' to the wild-type murine c-myc gene.
3.	165-1a or S line	MMTV/myc; mouse mammary tumor virus promoter fused to mouse c-myc oncogene with normal myc promoters deleted
4.	c-myc/tax	The HTLV-I/c-myc construct contains the entire U3 and R regions and 105 bp of the U5 region from the HTLV-I 3' LTR placed 5' to the wild-type murine c-myc gene. The Ig/....
5.	c-myc (+/-)	The targeting construct contains 10.6-kb of the mouse genomic c-myc sequence extending from the NheI site in intron 1 to an XbaI site 3' of the cod....
6.	c-myc (-/-)	The targeting construct contains 10.6-kb of the mouse genomic c-myc sequence extending from the NheI site in intron 1 to an XbaI site 3' of the cod....